DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT4G36140

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_195337.1	Gene:	AT4G36140 / 829771	AraportID:	AT4G36140	Length:	1607	Species:	Arabidopsis thaliana

Alignment Length:	213	Identity:	58/213 - (27%)
Similarity:	88/213 - (41%)	Gaps:	43/213 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 LVSLDLAYNDLKQLDQFPEGFSSIRSLQL-------QSNELPSLPDNFFAVTHARLETLNV-SCN 240
            ||.|:|:|:.|::|      ::..:||::       .|.:|.::.|...|   ..:|.::: .|.
plant  1011 LVELNLSYSQLQKL------WAGTKSLEMLKVVKLCHSQQLTAIDDILKA---QNIELIDLQGCR 1066

  Fly   241 KLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELE 305
            ||...|...|..|..:||||  |.....|..|...|   :..|||....|..||.:.|..:.:.:
plant  1067 KLQRFPATGQLQHLRVVNLS--GCREIKSFPEVSPN---IEELHLQGTGIRELPISIVSLFEQAK 1126

  Fly   306 ILVLSGNMLQQLPEEVATLGQLRVLRCCNN--------LLLCTPQLAKLAMLKVLDLSHNHLDRV 362
               |:..:...|||...      |....||        |:..|..|.||..|.:.|..|..
plant  1127 ---LNRELFNLLPEFSG------VSNAWNNEQSTSLAKLVTSTQNLGKLVCLNMKDCVHLR---- 1178

  Fly   363 NLLALVPSRNLKYLDLSG 380
            .|..:|...:||.|:|||
plant  1179 KLPYMVDFESLKVLNLSG 1196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380	7/24 (29%)
		LRR_8	205..266	CDD:290566	18/68 (26%)
		leucine-rich repeat	210..230	CDD:275380	5/26 (19%)
		leucine-rich repeat	232..255	CDD:275380	7/23 (30%)
		LRR_RI	<256..410	CDD:238064	38/133 (29%)
		leucine-rich repeat	256..276	CDD:275380	7/19 (37%)
		LRR_8	279..359	CDD:290566	22/87 (25%)
		leucine-rich repeat	280..303	CDD:275380	7/22 (32%)
		leucine-rich repeat	304..348	CDD:275380	12/51 (24%)
		leucine-rich repeat	349..372	CDD:275380	5/22 (23%)
		PP2Cc	461..655	CDD:294085
AT4G36140	NP_195337.1	TIR	50..259	CDD:279864
		AAA_17	291..>325	CDD:289950
		PLN03210	449..>1269	CDD:215633	58/213 (27%)
		TIR	449..579	CDD:279864
		AAA_16	607..716	CDD:289934
		leucine-rich repeat	960..988	CDD:275380
		leucine-rich repeat	989..1010	CDD:275380
		LRR_3	1010..1029	CDD:285026	7/23 (30%)
		leucine-rich repeat	1011..1033	CDD:275380	9/27 (33%)
		leucine-rich repeat	1034..1056	CDD:275380	4/24 (17%)
		leucine-rich repeat	1057..1079	CDD:275380	6/21 (29%)
		leucine-rich repeat	1080..1100	CDD:275380	7/21 (33%)
		leucine-rich repeat	1101..1143	CDD:275380	12/50 (24%)
		leucine-rich repeat	1166..1188	CDD:275380	6/25 (24%)
		leucine-rich repeat	1210..1229	CDD:275380
		leucine-rich repeat	1230..1251	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000