DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT4G14370

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001329614.1	Gene:	AT4G14370 / 827081	AraportID:	AT4G14370	Length:	1051	Species:	Arabidopsis thaliana

Alignment Length:	333	Identity:	72/333 - (21%)
Similarity:	125/333 - (37%)	Gaps:	60/333 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 HP-LPVEVTAAEEEQAATFGQTSP----QKLSL-KGSQLGGSILIGNYNYLTQLEV--CENEMEV 82
            || ..||:...|.:....:..|.|    :|:.| :.|.|.....:.|...|.:||:  |::.:|:
plant   600 HPEYLVELDMKESQLEKLWQGTQPLTNLKKMDLTRSSHLKELPDLSNATNLERLELSYCKSLVEI 664

  Fly    83 -LDLSSLAQLETL---KCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHP-VPLKLQRIDIS 142
             ...|.|.:||||   .|::.:::..:||..:|     |...:|........| :...:.|:.|.
plant   665 PSSFSELRKLETLVIHNCTKLEVVPTLINLASL-----DFFNMHGCFQLKKFPGISTHISRLVID 724

  Fly   143 HNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLK--QLDQFPEGFS 205
            .....|||..:..|..|..:..|.:         .|::....:.|.|.|.||:  .:::.|:...
plant   725 DTLVEELPTSIILCTRLRTLMISGS---------GNFKTLTYLPLSLTYLDLRCTGIEKIPDWIK 780

  Fly   206 SIRSLQL-------QSNELPSLPDNFFAVTHARLETL-NVSCNKLSTLPRYEQNN--HAALVNLS 260
            .:..|..       ....||.||.:...:.....|:| :|:|  :|:|..:...|  :...:|..
plant   781 DLHELSFLHIGGCRNLKSLPQLPLSIRWLNACDCESLESVAC--VSSLNSFVDLNFTNCFKLNQE 843

  Fly   261 LAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLG 325
            ...:.:..|.|..|.                :||.   |..||.......||:|...||..:...
plant   844 TRRDLIQQSFFRSLR----------------ILPG---REVPETFNHQAKGNVLTIRPESDSQFS 889

  Fly   326 QLRVLRCC 333
            .....:.|
plant   890 ASSRFKAC 897

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	7/21 (33%)
		LRR_8	109..169	CDD:290566	12/60 (20%)
		leucine-rich repeat	111..135	CDD:275380	4/24 (17%)
		leucine-rich repeat	136..158	CDD:275380	6/21 (29%)
		leucine-rich repeat	159..183	CDD:275380	3/23 (13%)
		leucine-rich repeat	184..209	CDD:275380	6/26 (23%)
		LRR_8	205..266	CDD:290566	13/70 (19%)
		leucine-rich repeat	210..230	CDD:275380	5/26 (19%)
		leucine-rich repeat	232..255	CDD:275380	7/25 (28%)
		LRR_RI	<256..410	CDD:238064	15/78 (19%)
		leucine-rich repeat	256..276	CDD:275380	4/19 (21%)
		LRR_8	279..359	CDD:290566	11/55 (20%)
		leucine-rich repeat	280..303	CDD:275380	3/22 (14%)
		leucine-rich repeat	304..348	CDD:275380	6/30 (20%)
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085
AT4G14370	NP_001329614.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000