DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT4G08450

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_192585.1	Gene:	AT4G08450 / 826403	AraportID:	AT4G08450	Length:	1234	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	99/382 - (25%)
Similarity:	157/382 - (41%)	Gaps:	91/382 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LKGSQLGGSILIGNYNYLTQLEVCENEMEVLDLSSLAQLETLK---C-----------SRNKLME 103
            ||...|.||               ||..|..:||....||||.   |           :.|||..
plant   634 LKNMNLFGS---------------ENLKEFPNLSLATNLETLSLGFCLSLVEVPSTIGNLNKLTY 683

  Fly   104 LIINGT-NLQTLVADHN-------YLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLT 160
            |.::|. ||:...||.|       .|:..|.....|.        || :|.|||      |.:..
plant   684 LNMSGCHNLEKFPADVNLKSLSDLVLNGCSRLKIFPA--------IS-SNISEL------CLNSL 733

  Fly   161 AIN--ASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQ-SNELPSLPD 222
            |:.  .|:..|.|:..||    |..:.|:.| ::.:|.|       :|::::.|: |..|..:||
plant   734 AVEEFPSNLHLENLVYLL----IWGMTSVKL-WDGVKVL-------TSLKTMHLRDSKNLKEIPD 786

  Fly   223 NFFAVTHARLETLNV-SCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLA 286
            ...|   :.|..||: .|..:..||...:|.| .|:.|.::| ..|...|....|...|:.::||
plant   787 LSMA---SNLLILNLEQCISIVELPSSIRNLH-NLIELDMSG-CTNLETFPTGINLQSLKRINLA 846

  Fly   287 -YNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLR--VLRCCNNLLLCTPQLAKLAM 348
             .:|:.:.|.... |..||:   ||...::::|..:....:|:  ::..||.|......::||..
plant   847 RCSRLKIFPDIST-NISELD---LSQTAIEEVPLWIENFSKLKYLIMGKCNMLEYVFLNISKLKH 907

  Fly   349 LKVLDLSH-NHLDRVNLLAL-VPSRNLKYLDLSGNLQL---QVDEQQFKVCQSQSQR 400
            ||.:|.|. ..|.:.::..| ||:      :.|.:|.:   |..|..|..|...:|:
plant   908 LKSVDFSDCGILSKADMYMLQVPN------EASSSLPINCVQKAELIFINCYKLNQK 958

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	10/33 (30%)
		LRR_8	109..169	CDD:290566	17/69 (25%)
		leucine-rich repeat	111..135	CDD:275380	7/30 (23%)
		leucine-rich repeat	136..158	CDD:275380	7/21 (33%)
		leucine-rich repeat	159..183	CDD:275380	7/25 (28%)
		leucine-rich repeat	184..209	CDD:275380	5/24 (21%)
		LRR_8	205..266	CDD:290566	18/62 (29%)
		leucine-rich repeat	210..230	CDD:275380	6/20 (30%)
		leucine-rich repeat	232..255	CDD:275380	8/23 (35%)
		LRR_RI	<256..410	CDD:238064	38/153 (25%)
		leucine-rich repeat	256..276	CDD:275380	5/19 (26%)
		LRR_8	279..359	CDD:290566	21/83 (25%)
		leucine-rich repeat	280..303	CDD:275380	6/23 (26%)
		leucine-rich repeat	304..348	CDD:275380	10/45 (22%)
		leucine-rich repeat	349..372	CDD:275380	8/24 (33%)
		PP2Cc	461..655	CDD:294085
AT4G08450	NP_192585.1	PLN03210	2..1197	CDD:215633	99/382 (26%)
		TIR	11..171	CDD:279864
		AAA_16	203..324	CDD:289934
		leucine-rich repeat	558..587	CDD:275380
		leucine-rich repeat	589..619	CDD:275380
		LRR_3	610..628	CDD:285026
		leucine-rich repeat	657..680	CDD:275380	5/22 (23%)
		leucine-rich repeat	681..703	CDD:275380	8/21 (38%)
		leucine-rich repeat	704..724	CDD:275380	5/28 (18%)
		leucine-rich repeat	725..746	CDD:275380	7/26 (27%)
		leucine-rich repeat	747..769	CDD:275380	7/33 (21%)
		leucine-rich repeat	770..792	CDD:275380	6/24 (25%)
		leucine-rich repeat	793..816	CDD:275380	8/23 (35%)
		leucine-rich repeat	817..839	CDD:275380	6/22 (27%)
		leucine-rich repeat	863..883	CDD:275380	5/22 (23%)
		leucine-rich repeat	884..907	CDD:275380	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000