DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT3G51560

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_190724.1	Gene:	AT3G51560 / 824319	AraportID:	AT3G51560	Length:	1253	Species:	Arabidopsis thaliana

Alignment Length:	578	Identity:	119/578 - (20%)
Similarity:	216/578 - (37%)	Gaps:	155/578 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LKVSASHSGPH---PLPVEVTAAEEEQAATFGQTSPQKLSLKGSQLGGSILIGNYNY-------- 69
            ||:.:|:.|.|   .||..|.:..||......:..| .|||.......:::|.|..|
plant   523 LKICSSNPGNHYALHLPKGVKSLPEELRLLHWEHFP-LLSLPQDFNTRNLVILNMCYSKLQRLWE 586

  Fly    70 -------LTQLEVCENE-------------MEVLDLSSLAQLETL---------------KCSRN 99
                   |.::.:|.::             |||:||...|:|:..               .|.:.
plant   587 GTKELGMLKRIMLCHSQQLVGIQELQIALNMEVIDLQGCARLQRFLATGHFQHLRVINLSGCIKI 651

  Fly   100 K--------LMELIINGTNLQTLVA---------------DHNYLHNISTTNTHPVPL-----KL 136
            |        :.||.:..|.::::..               ||.:|:...::::..:.:     .|
plant   652 KSFPEVPPNIEELYLKQTGIRSIPTVTFSPQDNSFIYDHKDHKFLNREVSSDSQSLSIMVYLDNL 716

  Fly   137 QRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFP 201
            :.:|:|  ...||.:..|...:|..:......:..:..|:   .::|||.|||  .:.|:|.:.|
plant   717 KVLDLS--QCLELEDIQGIPKNLRKLYLGGTAIKELPSLM---HLSELVVLDL--ENCKRLHKLP 774

  Fly   202 EGFSSIRSLQL-------QSNELPSLPDN----FFA----------VTH-ARLETLNV-SCNKLS 243
            .|..::.||.:       :..::..:|.|    :.|          :.| :.|..|:: :|.:|.
plant   775 MGIGNLSSLAVLNLSGCSELEDIQGIPRNLEELYLAGTAIQEVTSLIKHLSELVVLDLQNCKRLQ 839

  Fly   244 TLPRYEQNNHAALVNLSL---AGNHLNDSIFEPLHNA------AKLRVLHLAYN-----RIGVLP 294
            .|| .|.:|..:||.|.|   :|..:.:.....:.|.      :.|..|.|.:|     |...||
plant   840 HLP-MEISNLKSLVTLKLTDPSGMSIREVSTSIIQNGISEIGISNLNYLLLTFNENAEQRREYLP 903

  Fly   295 A---------ACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTP----QLAKL 346
            .         ..|..:..|..|.|....|..:|||:.:|..:.:|....|.....|    ||:||
plant   904 RPRLPSSSLHGLVPRFYALVSLSLFNASLMHIPEEICSLPSVVLLDLGRNGFSKIPESIKQLSKL 968

  Fly   347 AMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNN 411
            ..|::     .|...:.||..:| ::||.|::.|.:.|:.....|:    |...|::..|....:
plant   969 HSLRL-----RHCRNLILLPALP-QSLKLLNVHGCVSLESVSWGFE----QFPSHYTFSDCFNKS 1023

  Fly   412 ------RAALPTTKIRQVSAQRNQNKTSGPWTMGFAET-PGSGDCRKLSVYQLRAANY 462
                  |......|:..:..:..|....   .:.|:.. |...|  :.:.|.|||.::
plant  1024 PKVARKRVVKGLAKVASIGNEHQQELIK---ALAFSICGPAGAD--QATSYNLRAGSF 1076

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	5/41 (12%)
		LRR_8	109..169	CDD:290566	11/79 (14%)
		leucine-rich repeat	111..135	CDD:275380	3/43 (7%)
		leucine-rich repeat	136..158	CDD:275380	6/21 (29%)
		leucine-rich repeat	159..183	CDD:275380	2/23 (9%)
		leucine-rich repeat	184..209	CDD:275380	9/24 (38%)
		LRR_8	205..266	CDD:290566	19/86 (22%)
		leucine-rich repeat	210..230	CDD:275380	5/41 (12%)
		leucine-rich repeat	232..255	CDD:275380	8/23 (35%)
		LRR_RI	<256..410	CDD:238064	43/180 (24%)
		leucine-rich repeat	256..276	CDD:275380	5/22 (23%)
		LRR_8	279..359	CDD:290566	24/97 (25%)
		leucine-rich repeat	280..303	CDD:275380	8/36 (22%)
		leucine-rich repeat	304..348	CDD:275380	15/47 (32%)
		leucine-rich repeat	349..372	CDD:275380	5/22 (23%)
		PP2Cc	461..655	CDD:294085	0/2 (0%)
AT3G51560	NP_190724.1	TIR	6..155	CDD:279864
		AAA_16	181..270	CDD:289934
		LRR_RI	547..836	CDD:238064	52/296 (18%)
		LRR_3	570..589	CDD:285026	3/18 (17%)
		leucine-rich repeat	662..680	CDD:275380	3/17 (18%)
		leucine-rich repeat	737..758	CDD:275380	2/23 (9%)
		leucine-rich repeat	759..782	CDD:275380	9/24 (38%)
		leucine-rich repeat	804..826	CDD:275380	2/21 (10%)
		leucine-rich repeat	827..850	CDD:275380	8/23 (35%)
		leucine-rich repeat	851..883	CDD:275380	6/31 (19%)
		leucine-rich repeat	922..944	CDD:275380	8/21 (38%)
		leucine-rich repeat	945..967	CDD:275380	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000