DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and PIRL2

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_189281.2 Gene:PIRL2 / 822257 AraportID:AT3G26500 Length:471 Species:Arabidopsis thaliana


Alignment Length:466 Identity:108/466 - (23%)
Similarity:177/466 - (37%) Gaps:142/466 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 DPYKSKLKVSASHSGPHPLPVEVTAAEEEQAATFGQTSPQKL--SLKGSQLGGSILIGNYNYLTQ 72
            |.|:.|||.:.....      .|.:.|.|.....|:...:|:  .||.::.||::          
plant   114 DSYEKKLKDTEEELS------RVYSTEVESMLRSGEEVNEKVLAVLKEAESGGTV---------- 162

  Fly    73 LEVCENEMEVLDLSSLAQLETLKCSRNKLMELI---INGTNLQTLVADHNYLHNISTTNTHPVPL 134
                    |.:|||| .:|:.:..:..|::.|:   ::|.:| |.:.|     .||...      
plant   163 --------ERIDLSS-QELKLIPEAFWKVVGLVYLNLSGNDL-TFIPD-----AISKLK------ 206

  Fly   135 KLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQ 199
            ||:.:|:|.|:...||:.:|...:|..:|.:.|.|..:...:.:.|  .||.||.:||:      
plant   207 KLEELDVSSNSLESLPDSIGMLLNLRILNVNANNLTALPESIAHCR--SLVELDASYNN------ 263

  Fly   200 FPEGFSSIRSLQLQSNELPSLPDNF-FAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAG 263
                             |.|||.|. :.:.:  ||.|::..|||    ||...:.:.:.||....
plant   264 -----------------LTSLPTNIGYGLQN--LERLSIQLNKL----RYFPGSISEMYNLKYLD 305

  Fly   264 NHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNM--LQQLPEEVATLGQ 326
            .|:|:              :|...|.||.|        .:||:|.||.|.  |..:|:.:..|..
plant   306 AHMNE--------------IHGIPNSIGRL--------TKLEVLNLSSNFNNLMGVPDTITDLTN 348

  Fly   327 LRVLRCCNNLLLCTP-QLAKLAMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGNLQLQVDEQQ 390
            ||.|...||.:...| ...:|..|:.|:|..|.|:       :||:             :|..|.
plant   349 LRELDLSNNQIQAIPDSFYRLRKLEKLNLDQNPLE-------IPSQ-------------EVATQG 393

  Fly   391 FKVCQSQSQRHWSLVDVSGNNRAALPTTKIRQVSAQRN--------------QNKTSG-PWTMGF 440
            .:|.:...::.|..:......|..        |.|:|:              .|..|| ..|:||
plant   394 AEVVREFMRKRWGDIMAEQQQRIG--------VEAERHGDENGWVYWGTSMVTNLVSGVTHTIGF 450

  Fly   441 AETPGSGDCRK 451
            ......|..:|
plant   451 GGATSDGGDKK 461

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380 4/21 (19%)
LRR_8 109..169 CDD:290566 16/59 (27%)
leucine-rich repeat 111..135 CDD:275380 5/23 (22%)
leucine-rich repeat 136..158 CDD:275380 7/21 (33%)
leucine-rich repeat 159..183 CDD:275380 5/23 (22%)
leucine-rich repeat 184..209 CDD:275380 6/24 (25%)
LRR_8 205..266 CDD:290566 15/61 (25%)
leucine-rich repeat 210..230 CDD:275380 5/20 (25%)
leucine-rich repeat 232..255 CDD:275380 8/22 (36%)
LRR_RI <256..410 CDD:238064 36/156 (23%)
leucine-rich repeat 256..276 CDD:275380 4/19 (21%)
LRR_8 279..359 CDD:290566 25/82 (30%)
leucine-rich repeat 280..303 CDD:275380 5/22 (23%)
leucine-rich repeat 304..348 CDD:275380 16/46 (35%)
leucine-rich repeat 349..372 CDD:275380 7/22 (32%)
PP2Cc 461..655 CDD:294085
PIRL2NP_189281.2 leucine-rich repeat 162..184 CDD:275380 7/40 (18%)
LRR_RI 169..408 CDD:238064 78/324 (24%)
LRR_8 184..241 CDD:290566 18/68 (26%)
leucine-rich repeat 185..207 CDD:275380 7/33 (21%)
leucine-rich repeat 208..230 CDD:275380 7/21 (33%)
LRR_8 230..288 CDD:290566 20/84 (24%)
leucine-rich repeat 231..253 CDD:275380 5/23 (22%)
leucine-rich repeat 254..277 CDD:275380 11/45 (24%)
leucine-rich repeat 278..300 CDD:275380 8/25 (32%)
leucine-rich repeat 301..323 CDD:275380 8/43 (19%)
LRR_8 322..382 CDD:290566 20/59 (34%)
leucine-rich repeat 324..348 CDD:275380 9/23 (39%)
leucine-rich repeat 349..371 CDD:275380 7/21 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45752
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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