DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT3G04220

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001326120.1	Gene:	AT3G04220 / 819577	AraportID:	AT3G04220	Length:	896	Species:	Arabidopsis thaliana

Alignment Length:	322	Identity:	77/322 - (23%)
Similarity:	116/322 - (36%)	Gaps:	122/322 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 YLTQLEVCENEMEVL--DLSSLAQLE--TLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNT 129
            :|.:|.:..:::|.|  .:..|..||  .|.|||| |.||    .:|.|            .||
plant   675 FLVKLCMPYSKLEKLWEGIQPLRNLEWLDLTCSRN-LKEL----PDLST------------ATN- 721

  Fly   130 HPVPLKLQRIDISH-NNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYND 193
                  |||:.|.. ::..:||:.:|...:|..||                 :.|.:|
plant   722 ------LQRLSIERCSSLVKLPSSIGEATNLKKIN-----------------LRECLS------- 756

  Fly   194 LKQLDQFPEGFSSIRSLQ----LQSNELPSLPDNFFAVTHARLETLN-VSCNKLSTLPRYEQNNH 253
               |.:.|..|.::.:||    .:.:.|..||.:|..:  |.:|:|. ..|:.|..||
plant   757 ---LVELPSSFGNLTNLQELDLRECSSLVELPTSFGNL--ANVESLEFYECSSLVKLP------- 809

  Fly   254 AALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLP 318
                  |..||..|            ||||.|         ..|              :.:.:||
plant   810 ------STFGNLTN------------LRVLGL---------REC--------------SSMVELP 833

  Fly   319 EEVATLGQLRV--LRCCNNLLLCTPQLAKLAMLKVLDLSHNHLDRVNLLALVPSR--NLKYL 376
            .....|..|:|  ||.|:.|:........|..|:.|||.       :..:|:||.  |:.||
plant   834 SSFGNLTNLQVLNLRKCSTLVELPSSFVNLTNLENLDLR-------DCSSLLPSSFGNVTYL 888

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	10/20 (50%)
		LRR_8	109..169	CDD:290566	14/60 (23%)
		leucine-rich repeat	111..135	CDD:275380	4/23 (17%)
		leucine-rich repeat	136..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..183	CDD:275380	3/23 (13%)
		leucine-rich repeat	184..209	CDD:275380	4/24 (17%)
		LRR_8	205..266	CDD:290566	16/65 (25%)
		leucine-rich repeat	210..230	CDD:275380	6/23 (26%)
		leucine-rich repeat	232..255	CDD:275380	6/23 (26%)
		LRR_RI	<256..410	CDD:238064	30/125 (24%)
		leucine-rich repeat	256..276	CDD:275380	4/19 (21%)
		LRR_8	279..359	CDD:290566	20/81 (25%)
		leucine-rich repeat	280..303	CDD:275380	6/22 (27%)
		leucine-rich repeat	304..348	CDD:275380	10/45 (22%)
		leucine-rich repeat	349..372	CDD:275380	7/24 (29%)
		PP2Cc	461..655	CDD:294085
AT3G04220	NP_001326120.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000