DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and AT2G17060

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_179298.2 Gene:AT2G17060 / 816211 AraportID:AT2G17060 Length:1195 Species:Arabidopsis thaliana


Alignment Length:560 Identity:113/560 - (20%)
Similarity:203/560 - (36%) Gaps:151/560 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 ADPYKSKLKVSASHSGPHPLPVEVTAAEEEQ---AATFGQTSPQKLSLKGSQLGGSILIGNY--- 67
            ||...|:::..|.:     |.:.:::...|.   .|||.:.....||.:.:.  |..:|.|:   
plant   494 ADDAASEVRDFAGN-----LLISISSGRLEMHDLMATFAKKLCSSLSNENNY--GYQMIWNHESF 551

  Fly    68 ---------NYLTQ--LEVCENEME-----VLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVA 116
                     .|:.|  .:|.|:||:     :||:|.:....||.   :|....:.|...|:...:
plant   552 NAAAKNKRMRYVNQPRKKVTESEMDNVMGILLDVSEMDNNMTLD---SKFFSEMCNLRYLKVYNS 613

  Fly   117 DHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRI 181
            ..:...::....|.|..||....::.:..:.:.|        |..::.:.|..|.:.:.|...:|
plant   614 QCSRDCDVGCKLTFPDGLKCSMENVRYLYWLQFP--------LKKLSKAFNPKNLIELNLPYSKI 670

  Fly   182 TELVSLDLAYNDLKQLDQFPE----------GFSSIRSLQLQS-NELPSLPDNFFAVTHARLET- 234
            |.|.......:.||.:|....          |..:||.|.|:. .||.:||...     ..:|: 
plant   671 TRLWKESKEISKLKWVDLSHSSELCDISGLIGAHNIRRLNLEGCIELKTLPQEM-----QEMESL 730

  Fly   235 --LNV-SCNKLSTLPRYEQNNHAALV------------------NLSLAGNHLNDSIFEPLHNAA 278
              ||: .|.:|.:||.::..:...|:                  .|.|.|..:. .|...:.|..
plant   731 IYLNLGGCTRLVSLPEFKLKSLKTLILSHCKNFEQFPVISECLEALYLQGTAIK-CIPTSIENLQ 794

  Fly   279 KLRVLHLAYNRIGVLPAACVRNWPELEILVLSG-NMLQQLPEEVATLGQLRV------------- 329
            ||.:|.|....:.|....|:.|...|:.|:||| :.|:..||...|:..:::             
plant   795 KLILLDLKDCEVLVSLPDCLGNLRSLQELILSGCSKLKFFPELKETMKSIKILLLDGTAIKQMPI 859

  Fly   330 -LRCCNN-----------------------LLLCT---------PQLAKLAMLKVLDLSHNHLDR 361
             |:|..:                       |.||.         ..:::|..||.|||  .:..:
plant   860 LLQCIQSQGHSVANKTLPNSLSDYYLPSSLLSLCLSGNDIESLHANISQLYHLKWLDL--KNCKK 922

  Fly   362 VNLLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNNRAALPTTKIRQVSAQ 426
            :..::::|. |||.||..|...|:.......|.....:.|.:.:..:.|....:..:.|...:.:
plant   923 LKSVSVLPP-NLKCLDAHGCDSLEEVGSPLAVLMVTGKIHCTYIFTNCNKLDQVAESNIISFTWR 986

  Fly   427 RNQ------NKTSGPWTMGF------------AETPGSGD 448
            ::|      |:.:|    ||            .|.|.|.|
plant   987 KSQMMSDALNRYNG----GFVLESLVSTCFPGCEVPASFD 1022

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380 4/18 (22%)
LRR_8 109..169 CDD:290566 8/59 (14%)
leucine-rich repeat 111..135 CDD:275380 3/23 (13%)
leucine-rich repeat 136..158 CDD:275380 1/21 (5%)
leucine-rich repeat 159..183 CDD:275380 5/23 (22%)
leucine-rich repeat 184..209 CDD:275380 6/34 (18%)
LRR_8 205..266 CDD:290566 19/83 (23%)
leucine-rich repeat 210..230 CDD:275380 6/20 (30%)
leucine-rich repeat 232..255 CDD:275380 7/26 (27%)
LRR_RI <256..410 CDD:238064 43/218 (20%)
leucine-rich repeat 256..276 CDD:275380 5/37 (14%)
LRR_8 279..359 CDD:290566 27/126 (21%)
leucine-rich repeat 280..303 CDD:275380 6/22 (27%)
leucine-rich repeat 304..348 CDD:275380 15/90 (17%)
leucine-rich repeat 349..372 CDD:275380 6/22 (27%)
PP2Cc 461..655 CDD:294085
AT2G17060NP_179298.2 TIR 17..153 CDD:214587
PLN03210 20..1072 CDD:215633 113/560 (20%)
AAA_16 219..>264 CDD:289934
LRR_3 659..678 CDD:285026 5/18 (28%)
leucine-rich repeat 660..682 CDD:275380 4/21 (19%)
leucine-rich repeat 706..729 CDD:275380 8/27 (30%)
leucine-rich repeat 730..751 CDD:275380 6/20 (30%)
leucine-rich repeat 773..795 CDD:275380 5/22 (23%)
leucine-rich repeat 796..819 CDD:275380 6/22 (27%)
leucine-rich repeat 844..911 CDD:275380 6/66 (9%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X32
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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