Protein Alignment Phlpp and chadla

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: XP_017210255.1
• Gene: chadla / 565474
• ZFINID: ZDB-GENE-121205-4
• Length: 791
• Species: Danio rerio
• Alignment Length: 691
• Identity: 157/691 - (22%)
• Similarity: 258/691 - (37%)
• Gaps: 148/691 - (21%)

  Fly    92 ETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELP-NWVGA 155
            :||||.|    ..:.:.|.|......:|..|...|.:...|     ::|:..|||.||| |....
Zfish    18 QTLKCPR----VCVCDNTKLTVKCIGNNLTHIPPTIDEIIV-----KLDLKKNNFGELPKNAFKH 73

  Fly   156 CASLTAINASHNRLNNVAVLLRNYR-ITELVSLDLAYNDLKQLDQFP-EGFSSIRSLQLQSNELP 218
            ...||.::.....:.  ||....:| ::.|:.|||..|::..|.|.. :|.||::.|.|..|.:.
Zfish    74 TPYLTQLSLQGCSVQ--AVREGAFRGLSRLLQLDLTNNNIDILYQESFDGLSSLKQLYLDRNRIE 136

  Fly   219 SLPDNFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVL 283
            .:....||..:: |..|:::.|:|..||.........:..|.|:.|.||:...|.......|..|
Zfish   137 EIHPGAFAALNS-LNLLSLTYNQLVYLPNMAFQGMMNIQMLHLSHNSLNNLATEAFAGLLALTHL 200

  Fly   284 HLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLL--LCTPQLAKL 346
            :|.:|.:...|...:....|:..|.:|.|.:..|.||...:.:|..|...:|.|  |....::..
Zfish   201 NLDHNELQYFPTKTMTRLIEVTHLDMSYNPMTYLVEESVVMPKLTHLSLKHNALQDLSESTISLS 265

  Fly   347 AMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGN----------LQL----------------- 384
            .::..||||.|.|..:.  ||..|.:|..|:|:||          |:|
Zfish   266 PVISHLDLSFNQLSYIQ--ALAASTHLTSLNLTGNPIRCTCLLRDLKLWALKSGIRLFGVCAWPP 328

  Fly   385 --------QVDEQQFKVCQSQSQRHWSLVDV---------SGNNRAALPTTKIR----------- 421
                    .|.||..: |:.|.:  |: .||         .|.....:.|.|.:
Zfish   329 HLSDEPLENVQEQDLR-CRPQDE--WT-SDVIEEGTKEEEEGVQEKTVSTAKSKKTRKCPKDCLC 389

  Fly   422 QVSAQ----RNQNKTSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEAL---EGR 479
            :.:||    .|:..|..|  .||.......|.|....:.|.:.::.|..|.:....::.   |..
Zfish   390 EYAAQHATCENRGHTKVP--SGFPRKTLLLDMRGNHFHYLPSKSFPGIPEVVSLHLDSCKIHEIE 452

  Fly   480 GRAAQEMSHLVPDLMKQEQMVK-DSAVRD---YMKFTLLAAQQQCGSVRSAALFHLTRTRAPSKV 540
            |.|.|.|.:|:...:...|:.. |:.|.:   .:.:..|...:......||.|.|:      .|:
Zfish   453 GGAFQGMKNLIYLYLSDNQLSSLDAKVFEGAHEIMYLHLEDNKLTHFPSSATLTHI------PKL 511

  Fly   541 RPLKSKRYVLRMASTGGLDAYLIRRTSQLRLT----------------KPDV--IQKDQIHSMPD 587
            ..|..:|.::......||.:.:::.|. |.|.                |.||  ::.:.:..:|.
Zfish   512 LELHLERNLIAKLEPSGLLSPVLQLTG-LYLNNNSIATIVPKALDPAPKLDVLHLEDNVLTDVPS 575

  Fly   588 ------PHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIRKEENSLLAAKRLVDIAQSFAAAE 646
                  |.:.||.||        ||...|..   .||.|.:.:...:||..:    :.....:..
Zfish   576 DALDHAPLLTELHLS--------GNLIRWIG---PRAFRVVAESLKNLLIDR----MGLQKMSVR 625

  Fly   647 SLSVIVVRFRHLGTDVDHLIRELKQ----------SVRKKP 677
            ||:....|...|..: |:|:.||..          |:.|.|
Zfish   626 SLAGFGPRLLSLSLE-DNLLEELPDLSPLAGLQNLSLNKNP 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	5/17 (29%)
		LRR_8	109..169	CDD:290566	16/60 (27%)
		leucine-rich repeat	111..135	CDD:275380	5/23 (22%)
		leucine-rich repeat	136..158	CDD:275380	8/22 (36%)
		leucine-rich repeat	159..183	CDD:275380	5/24 (21%)
		leucine-rich repeat	184..209	CDD:275380	10/25 (40%)
		LRR_8	205..266	CDD:290566	16/60 (27%)
		leucine-rich repeat	210..230	CDD:275380	5/19 (26%)
		leucine-rich repeat	232..255	CDD:275380	6/22 (27%)
		LRR_RI	<256..410	CDD:238064	47/199 (24%)
		leucine-rich repeat	256..276	CDD:275380	6/19 (32%)
		LRR_8	279..359	CDD:290566	22/81 (27%)
		leucine-rich repeat	280..303	CDD:275380	5/22 (23%)
		leucine-rich repeat	304..348	CDD:275380	11/45 (24%)
		leucine-rich repeat	349..372	CDD:275380	9/22 (41%)
		PP2Cc	461..655	CDD:294085	43/224 (19%)
chadla	XP_017210255.1	LRRNT	22..49	CDD:279764	6/30 (20%)
		leucine-rich repeat	55..76	CDD:275380	8/20 (40%)
		LRR_8	75..135	CDD:290566	18/61 (30%)
		leucine-rich repeat	77..100	CDD:275380	5/24 (21%)
		leucine-rich repeat	101..124	CDD:275380	8/22 (36%)
		leucine-rich repeat	125..148	CDD:275380	5/22 (23%)
		leucine-rich repeat	149..172	CDD:275380	6/22 (27%)
		LRR_8	172..231	CDD:290566	15/58 (26%)
		leucine-rich repeat	173..196	CDD:275380	6/22 (27%)
		leucine-rich repeat	197..220	CDD:275380	5/22 (23%)
		leucine-rich repeat	221..243	CDD:275380	6/21 (29%)
		LRR_8	242..300	CDD:290566	19/59 (32%)
		leucine-rich repeat	244..267	CDD:275380	5/22 (23%)
		leucine-rich repeat	417..437	CDD:275380	4/19 (21%)
		LRR_8	436..496	CDD:290566	11/59 (19%)
		leucine-rich repeat	438..461	CDD:275380	5/22 (23%)
		LRR_RI	<451..658	CDD:238064	46/229 (20%)
		leucine-rich repeat	462..485	CDD:275380	4/22 (18%)
		leucine-rich repeat	486..510	CDD:275380	5/29 (17%)
		leucine-rich repeat	511..535	CDD:275380	4/23 (17%)
		LRR_8	535..594	CDD:290566	14/67 (21%)
		leucine-rich repeat	536..559	CDD:275380	3/23 (13%)
		leucine-rich repeat	560..583	CDD:275380	3/22 (14%)
		leucine-rich repeat	584..608	CDD:275380	10/34 (29%)
		leucine-rich repeat	609..633	CDD:275380	4/27 (15%)
		leucine-rich repeat	634..656	CDD:275380	5/22 (23%)
		LRRCT	664..>699	CDD:214507	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000