Protein Alignment Phlpp and lrrc39

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: NP_001017760.1
• Gene: lrrc39 / 550456
• ZFINID: ZDB-GENE-050417-279
• Length: 343
• Species: Danio rerio
• Alignment Length: 208
• Identity: 60/208 - (28%)
• Similarity: 97/208 - (46%)
• Gaps: 16/208 - (7%)

  Fly   194 LKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVN 258
            |:::.:|...|.|:..|.|..|.:..:|.....:|  ||..|.:|.|::|.:|. |......|..
Zfish   100 LQRIPRFISSFQSLIVLDLSRNSVTEIPKEIGKLT--RLRELLLSYNRVSYVPE-ELGCCENLEK 161

  Fly   259 LSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVAT 323
            |.||.|...|.:...|.|..||..|.|:.|:...:| .||.|.|.||.|.:..|:|:.||:::..
Zfish   162 LELAMNQDLDELPTQLSNLKKLSHLDLSMNQFTTIP-DCVVNLPSLEWLDMGSNILETLPDDIHR 225

  Fly   324 LGQLRVLRCCNNLLLCTP-QLAKLAMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGN------ 381
            :.:|..|....|.|...| .::::..|..|.||.|.|..:..| :....||::::...|
Zfish   226 MEKLHTLWLPRNELEYLPDNISRMKSLDTLVLSKNKLRDIPPL-MEGMSNLRFVNFRDNPLTYDV 289

  Fly   382 ----LQLQVDEQQ 390
                |...|:|::
Zfish   290 TLPDLNEDVEEEE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380	4/14 (29%)
		LRR_8	205..266	CDD:290566	19/60 (32%)
		leucine-rich repeat	210..230	CDD:275380	5/19 (26%)
		leucine-rich repeat	232..255	CDD:275380	7/22 (32%)
		LRR_RI	<256..410	CDD:238064	43/146 (29%)
		leucine-rich repeat	256..276	CDD:275380	7/19 (37%)
		LRR_8	279..359	CDD:290566	27/80 (34%)
		leucine-rich repeat	280..303	CDD:275380	8/22 (36%)
		leucine-rich repeat	304..348	CDD:275380	12/44 (27%)
		leucine-rich repeat	349..372	CDD:275380	7/22 (32%)
		PP2Cc	461..655	CDD:294085
lrrc39	NP_001017760.1	LRR 1. /evidence=ECO:0000255	64..87
		LRR 2. /evidence=ECO:0000255	88..110		2/9 (22%)
		leucine-rich repeat	91..108	CDD:275380	2/7 (29%)
		LRR_RI	99..>286	CDD:238064	57/190 (30%)
		LRR 3. /evidence=ECO:0000255	111..133		5/21 (24%)
		leucine-rich repeat	113..135	CDD:275380	5/23 (22%)
		LRR 4. /evidence=ECO:0000255	134..156		9/24 (38%)
		leucine-rich repeat	136..158	CDD:275380	7/22 (32%)
		LRR_8	158..214	CDD:290566	21/56 (38%)
		LRR 5. /evidence=ECO:0000255	158..180		7/21 (33%)
		leucine-rich repeat	159..182	CDD:275380	8/22 (36%)
		LRR 6. /evidence=ECO:0000255	181..203		8/22 (36%)
		leucine-rich repeat	183..205	CDD:275380	8/22 (36%)
		LRR 7. /evidence=ECO:0000255	204..226		8/21 (38%)
		leucine-rich repeat	206..228	CDD:275380	7/21 (33%)
		LRR_8	228..285	CDD:290566	15/57 (26%)
		LRR 8. /evidence=ECO:0000255	228..249		5/20 (25%)
		leucine-rich repeat	229..251	CDD:275380	5/21 (24%)
		LRR 9. /evidence=ECO:0000255	250..274		7/24 (29%)
		leucine-rich repeat	252..274	CDD:275380	7/22 (32%)
		LRR 10. /evidence=ECO:0000255	275..295		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45752
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100