DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and ACXA

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_620475.2 Gene:ACXA / 53432 FlyBaseID:FBgn0040510 Length:1112 Species:Drosophila melanogaster


Alignment Length:306 Identity:68/306 - (22%)
Similarity:107/306 - (34%) Gaps:107/306 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 NYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVSCNKL 242
            ||::    :||| .|..|..|...:..     :.|.:|.|||             ..:.|..:.:
  Fly   813 NYKL----NLDL-QNKQKSADVTNQSI-----IILLNNILPS-------------HVVEVYLSSI 854

  Fly   243 STLPRYEQNNHAALVNLSLAGNH---------LNDSI--FEPLHNA-------AKLRVLHLAYNR 289
            :....|.:|.....|..::..|.         |||.|  |:.|.:|       .|::|:...|  
  Fly   855 AKHELYYENYRMVSVMFAMLTNFQMDLPSLRVLNDIITAFDRLLSAYKQYYVVEKIKVVGCTY-- 917

  Fly   290 IGVLPAACVRNWPELEILVLSGNM--------LQQL------------PEEVA------TLGQLR 328
                .|||..::..:|.|..:.|.        |:|:            .:|||      .|..:|
  Fly   918 ----MAACGLDFSLIENLDSNSNFGSTSLSSELEQVRSRLESSIKEKNHDEVAFIMATFALDLMR 978

  Fly   329 VLRCCNNLLLCTPQLAKLA-------------MLKVLDLSHNHLD----RVNLLALVPSRNLKYL 376
            ||..||......|....|:             |..|:..|..|.|    .||:.:.:.|..    
  Fly   979 VLSVCNKAYAGEPFDRALSTGEIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTG---- 1039

  Fly   377 DLSGNLQLQVDE----QQFKV-CQSQSQRHWSLVDVSGNNRAALPT 417
             |||::|:..:.    ::|.| |.     :..|..|.|  |..:||
  Fly  1040 -LSGHIQVTKETAQTLEEFDVMCY-----YRGLTFVKG--RGEIPT 1077

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380
LRR_8 109..169 CDD:290566
leucine-rich repeat 111..135 CDD:275380
leucine-rich repeat 136..158 CDD:275380
leucine-rich repeat 159..183 CDD:275380 2/4 (50%)
leucine-rich repeat 184..209 CDD:275380 6/24 (25%)
LRR_8 205..266 CDD:290566 10/69 (14%)
leucine-rich repeat 210..230 CDD:275380 5/19 (26%)
leucine-rich repeat 232..255 CDD:275380 3/22 (14%)
LRR_RI <256..410 CDD:238064 48/219 (22%)
leucine-rich repeat 256..276 CDD:275380 8/30 (27%)
LRR_8 279..359 CDD:290566 25/118 (21%)
leucine-rich repeat 280..303 CDD:275380 5/22 (23%)
leucine-rich repeat 304..348 CDD:275380 16/82 (20%)
leucine-rich repeat 349..372 CDD:275380 7/26 (27%)
PP2Cc 461..655 CDD:294085
ACXANP_620475.2 AC_N <42..291 CDD:292831
CYCc 262..464 CDD:214485
Nucleotidyl_cyc_III 306..489 CDD:299850
CYCc 831..1055 CDD:214485 51/252 (20%)
Nucleotidyl_cyc_III 859..1080 CDD:299850 54/237 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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