DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and lrfn1

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_956909.1 Gene:lrfn1 / 393587 ZFINID:ZDB-GENE-040426-1227 Length:584 Species:Danio rerio


Alignment Length:243 Identity:59/243 - (24%)
Similarity:96/243 - (39%) Gaps:94/243 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 NYLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLMEL----------------------IING-- 108
            |::|.:    ...:.|:::||..| ||  |||.:.::                      :||.  
Zfish    61 NFITAV----RRKDFLNMTSLVHL-TL--SRNTISQIAPHAFMGLKSLRALHMDGNRLSVINSDQ 118

  Fly   109 ----TNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINA---SH 166
                .||:.|:..:|.:|:|..::.......::.:|:|:||...|| | .|.|.:|.||.   .|
Zfish   119 LKGLMNLRHLILGNNQIHHIEESSFDEFVATIEDLDLSYNNLRTLP-W-EAIARMTNINTLTLDH 181

  Fly   167 NRLNNVAV----LLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAV 227
            |.::::.|    ||     |:||.||:..|.|:.|.                      ||..|  
Zfish   182 NLIDHIGVGTFTLL-----TKLVRLDMTSNRLQTLP----------------------PDTLF-- 217

  Fly   228 THARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLH 275
            .||::    :|..|.|:..|         :.:|..||        |||
Zfish   218 QHAQV----LSEPKTSSSSR---------LTVSFGGN--------PLH 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380 8/46 (17%)
LRR_8 109..169 CDD:290566 20/62 (32%)
leucine-rich repeat 111..135 CDD:275380 5/23 (22%)
leucine-rich repeat 136..158 CDD:275380 8/21 (38%)
leucine-rich repeat 159..183 CDD:275380 8/30 (27%)
leucine-rich repeat 184..209 CDD:275380 7/24 (29%)
LRR_8 205..266 CDD:290566 12/60 (20%)
leucine-rich repeat 210..230 CDD:275380 3/19 (16%)
leucine-rich repeat 232..255 CDD:275380 4/22 (18%)
LRR_RI <256..410 CDD:238064 6/20 (30%)
leucine-rich repeat 256..276 CDD:275380 6/20 (30%)
LRR_8 279..359 CDD:290566
leucine-rich repeat 280..303 CDD:275380
leucine-rich repeat 304..348 CDD:275380
leucine-rich repeat 349..372 CDD:275380
PP2Cc 461..655 CDD:294085
lrfn1NP_956909.1 LRR 1 52..73 2/15 (13%)
LRR_8 55..111 CDD:290566 11/56 (20%)
leucine-rich repeat 55..76 CDD:275380 3/18 (17%)
LRR_RI <71..>208 CDD:238064 40/146 (27%)
LRR 2 76..97 8/23 (35%)
leucine-rich repeat 77..100 CDD:275380 7/25 (28%)
LRR_8 99..160 CDD:290566 11/60 (18%)
LRR 3 100..121 2/20 (10%)
leucine-rich repeat 101..124 CDD:275380 2/22 (9%)
LRR 4 124..145 6/20 (30%)
leucine-rich repeat 125..148 CDD:275380 5/22 (23%)
LRR 5 149..170 8/22 (36%)
leucine-rich repeat 150..173 CDD:275380 9/24 (38%)
LRR_8 153..208 CDD:290566 23/61 (38%)
LRR 6 173..194 5/20 (25%)
leucine-rich repeat 174..197 CDD:275380 7/27 (26%)
LRR 7 197..218 10/44 (23%)
leucine-rich repeat 198..222 CDD:275380 12/47 (26%)
LRRCT 241..>270 CDD:214507 4/12 (33%)
IG_like 299..375 CDD:214653
Ig_2 303..376 CDD:143241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 393..414
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 539..564
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X32
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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