Protein Alignment Phlpp and Gp150

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: NP_477049.2
• Gene: Gp150 / 37549
• FlyBaseID: FBgn0013272
• Length: 1076
• Species: Drosophila melanogaster
• Alignment Length: 812
• Identity: 165/812 - (20%)
• Similarity: 293/812 - (36%)
• Gaps: 240/812 - (29%)

  Fly    64 IGNYNYLTQLEVCENEMEVLD----LSSLAQLETLKCSRNKLMELIING-TNLQTLVADHNYLHN 123
            :|| ..|..|.:..|::.|:.    |...:.:|.|..|||.||||.... ::|..:|    |: |
  Fly   362 VGN-KKLRMLTISGNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVV----YI-N 420

  Fly   124 ISTTNTHPVPLK-------LQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRI 181
            :|..:...:|.|       |:.:|:|:|:.:|||..:....:|:.::..:|..|...    ::..
  Fly   421 LSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNGTTLSILHLKYNTFNGDL----HFGT 481

  Fly   182 TELVSLDLAYNDLKQL-----DQFPEGFSSIRSLQLQSNELPSL-PDNFFAVTHARLETLNVSCN 240
            .:|..|||::|.:.|:     |:.|    .:.:|.|:.|.:..: ||:|  :|...|..:::|.|
  Fly   482 KDLQQLDLSFNSIVQVHHSMFDKMP----GLTNLNLKGNGIKKIQPDSF--LTLKNLRHIDLSIN 540

  Fly   241 KLSTLP--RYEQNNHAALVNLSLAGNHLNDSIFEP----------LHNAAKLRVLHLAYNR--IG 291
            .|..:.  .:.:|:...::       .|||:   |          |..:.:..|.:|..:.  ||
  Fly   541 DLDQISGMLFFKNSELDVI-------RLNDN---PRLSQLPTDGFLSYSGEFTVYYLDISNCAIG 595

  Fly   292 VLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQLAKLAMLKVLDLSH 356
            .|........|.|..|.|:.|.:..||.|:.|                     .|..|..||||:
  Fly   596 PLGHKAFSTMPHLTTLKLAWNNINHLPREIFT---------------------GLHKLIDLDLSN 639

  Fly   357 NHLDRVNLLALVPSRNLKYLDLSGN--LQLQVDEQQFKVCQSQSQRHWSLVDVSGNNRAALPTTK 419
            |.:.|::.|..:.:..|..|.|:||  .:|.|                         |..||..:
  Fly   640 NLITRMDDLIFMDNGELTKLSLAGNPISRLSV-------------------------RLFLPLHQ 679

  Fly   420 IRQVSAQRNQNKTSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQ 484
            :|.:..                     .||...::...|....|      |.:|::|.....:.
  Fly   680 LRCLDV---------------------NDCELTTLLSDRDLGAG------YKIFDSLRSFNASG- 716

  Fly   485 EMSHLVPDLMKQEQMVKDSAVRDYMKFTLLAAQQQCGSVRSAALFHLTRTRAPSKVRPLKSKRYV 549
                         .::|..:..|...|.         ::||     |..|..|.|..|
  Fly   717 -------------NLIKKISSEDVKSFK---------NLRS-----LDITNNPLKCTP------- 747

  Fly   550 LRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHSMPDPHVLELILSNDDEYLVVGNAQL----W 610
                   ....::...|.|:::|               |..|.::.:.:|:..:|....|    |
  Fly   748 -------DFQEFISYVTLQMQMT---------------PKRLPVLANLEDDATIVQLETLAQAGW 790

  Fly   611 SVMDIDRAAREIRKE-ENSLLAAKRLVDIAQSFAAAESLSVIVVRFRHLGTDVDHLIRELKQSVR 674
            |.:     |.|:.|. |.|.|..::..|.|:    |:....:....:.|..|...|:..|.:||.
  Fly   791 SSL-----AHEVCKHAEGSDLLDEKKADSAE----AKLEKRLKESVKKLNEDEAKLLSVLDKSVL 846

  Fly   675 KKPQPVSL-PLSSGSVCKRTCCDRSNACRHRAIEQEPL--AGRSSPSGQSDRDLLAKDKDD---- 732
            .|.:..|: .:..|||...|.....:|      ::|.|  .|.......||.|....|.||
  Fly   847 DKSRLSSMQKIMKGSVNTETAKPEEDA------DEENLNNGGEDKEDDSSDYDSEEDDDDDDEDD 905

  Fly   733 ----------EFVLAHARVLQE---------EQQLEMLDETESVSESVLSEEQFKCWEYMLEQNT 778
                      |....:|:...:         .::|:.:.:|:.:....:...|....:::||
  Fly   906 DDDNNDDDRFEEAKKNAKAKADANKAFDTFVNKELKPVLKTDGIQAEEVDMSQETRDKFLLE--- 967

  Fly   779 QLLFDKELNTISKSFTKQRTVPNAIMAATVLP 810
            :|.||.| :..|..:|::......:....|:|
  Fly   968 KLGFDSE-SEESDEYTEKMIFHGELSYDLVVP 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	9/19 (47%)
		LRR_8	109..169	CDD:290566	16/66 (24%)
		leucine-rich repeat	111..135	CDD:275380	6/23 (26%)
		leucine-rich repeat	136..158	CDD:275380	7/21 (33%)
		leucine-rich repeat	159..183	CDD:275380	3/23 (13%)
		leucine-rich repeat	184..209	CDD:275380	8/29 (28%)
		LRR_8	205..266	CDD:290566	12/63 (19%)
		leucine-rich repeat	210..230	CDD:275380	7/20 (35%)
		leucine-rich repeat	232..255	CDD:275380	5/24 (21%)
		LRR_RI	<256..410	CDD:238064	35/167 (21%)
		leucine-rich repeat	256..276	CDD:275380	5/29 (17%)
		LRR_8	279..359	CDD:290566	21/81 (26%)
		leucine-rich repeat	280..303	CDD:275380	5/24 (21%)
		leucine-rich repeat	304..348	CDD:275380	9/43 (21%)
		leucine-rich repeat	349..372	CDD:275380	8/22 (36%)
		PP2Cc	461..655	CDD:294085	33/198 (17%)
Gp150	NP_477049.2	LRR_8	317..377	CDD:290566	5/15 (33%)
		leucine-rich repeat	343..366	CDD:275380	2/4 (50%)
		leucine-rich repeat	367..391	CDD:275380	5/23 (22%)
		LRR_RI	<374..619	CDD:238064	64/269 (24%)
		LRR_8	390..450	CDD:290566	20/64 (31%)
		leucine-rich repeat	393..415	CDD:275380	10/21 (48%)
		leucine-rich repeat	416..439	CDD:275380	6/27 (22%)
		leucine-rich repeat	440..483	CDD:275380	10/46 (22%)
		leucine-rich repeat	463..481	CDD:275380	3/21 (14%)
		LRR_8	484..542	CDD:290566	18/63 (29%)
		leucine-rich repeat	484..507	CDD:275380	8/26 (31%)
		leucine-rich repeat	508..531	CDD:275380	7/24 (29%)
		leucine-rich repeat	532..569	CDD:275380	9/46 (20%)
		leucine-rich repeat	556..583	CDD:275380	5/36 (14%)
		leucine-rich repeat	570..607	CDD:275380	6/36 (17%)
		LRR_RI	<586..745	CDD:238064	48/259 (19%)
		LRR_8	606..666	CDD:290566	23/80 (29%)
		leucine-rich repeat	608..631	CDD:275380	9/43 (21%)
		leucine-rich repeat	632..655	CDD:275380	8/22 (36%)
		leucine-rich repeat	656..674	CDD:275380	8/42 (19%)
		leucine-rich repeat	733..745	CDD:275378	5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910