DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and CG32687

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_001259412.1 Gene:CG32687 / 31980 FlyBaseID:FBgn0052687 Length:377 Species:Drosophila melanogaster


Alignment Length:300 Identity:84/300 - (28%)
Similarity:134/300 - (44%) Gaps:68/300 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   174 VLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVS 238
            :||.:.|:..|..|.|.:.:||.||             |.||.:.:|||   ||....|.||...
  Fly    52 MLLNHNRLVGLPRLLLQFGNLKILD-------------LSSNAITTLPD---AVCQLPLVTLIAK 100

  Fly   239 CNKL-------STLPRYEQNN---------HAALVNLSLAGN---HLNDSIFEPLHNAAKLRVLH 284
            .|.|       |.|.:....|         ::.|..|:|:||   |..:.:.|..|    |:.|:
  Fly   101 NNLLTNASLPKSLLTKMANGNGNGNATGGTNSTLKELNLSGNQLTHFPEQVTELRH----LKYLY 161

  Fly   285 LAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTP-QLAKLAM 348
            |..|:|..: :..:.....|.:|.|.||::.::||.|.:|.||:.|..|:||:...| .:|:|..
  Fly   162 LGGNKISSV-SKDIWKMQSLHVLSLGGNLISEVPEAVGSLNQLQALVLCDNLIEILPTSIARLKN 225

  Fly   349 LKVLDLSHNHLDRV--NLLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNN 411
            ||.|.|..|.|..:  :::||   :||..|.|..| .|.|     :..|..:.:..:|::::|  
  Fly   226 LKSLLLHKNRLRHLPKDIVAL---KNLTELSLRDN-PLVV-----RFVQDMALKPPTLLELAG-- 279

  Fly   412 RAALPTTKIRQVSAQRNQNKTSGPWTM--GFAETPGSGDC 449
                   ::.:.|.||     .||:.:  ..||...|.:|
  Fly   280 -------RMVKASGQR-----PGPYDIPRTLAEYLNSANC 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380
LRR_8 109..169 CDD:290566
leucine-rich repeat 111..135 CDD:275380
leucine-rich repeat 136..158 CDD:275380
leucine-rich repeat 159..183 CDD:275380 3/8 (38%)
leucine-rich repeat 184..209 CDD:275380 7/24 (29%)
LRR_8 205..266 CDD:290566 21/79 (27%)
leucine-rich repeat 210..230 CDD:275380 8/19 (42%)
leucine-rich repeat 232..255 CDD:275380 8/38 (21%)
LRR_RI <256..410 CDD:238064 48/159 (30%)
leucine-rich repeat 256..276 CDD:275380 7/22 (32%)
LRR_8 279..359 CDD:290566 28/80 (35%)
leucine-rich repeat 280..303 CDD:275380 5/22 (23%)
leucine-rich repeat 304..348 CDD:275380 18/44 (41%)
leucine-rich repeat 349..372 CDD:275380 8/24 (33%)
PP2Cc 461..655 CDD:294085
CG32687NP_001259412.1 leucine-rich repeat 72..92 CDD:275380 12/35 (34%)
leucine-rich repeat 94..133 CDD:275380 8/38 (21%)
LRR_8 132..190 CDD:290566 18/62 (29%)
LRR_4 134..171 CDD:289563 13/41 (32%)
leucine-rich repeat 134..156 CDD:275380 7/21 (33%)
leucine-rich repeat 157..179 CDD:275380 5/22 (23%)
leucine-rich repeat 180..202 CDD:275380 9/21 (43%)
LRR_8 202..259 CDD:290566 22/60 (37%)
leucine-rich repeat 203..225 CDD:275380 8/21 (38%)
leucine-rich repeat 226..248 CDD:275380 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45467259
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45752
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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