DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and Npr3

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	XP_006232107.1	Gene:	Npr3 / 25339	RGDID:	3196	Length:	652	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	34/150 - (22%)
Similarity:	51/150 - (34%)	Gaps:	49/150 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   528 LFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHSMPDPHVLE 592
            ||.|.|      |||  :..|.||.....|....|:...::.::...|
  Rat   177 LFSLAR------VRP--AIEYALRSVEGNGTGRKLLPPGTRFQVAYED----------------- 216

  Fly   593 LILSNDDEYLVVGNAQLWSVMDIDRAAREIRKE-------ENSLLAAKRLV---DIAQSFAAAES 647
                :|     .||..|:|::|...|||..:.:       |.:.....||.   |:....|.|
  Rat   217 ----SD-----CGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGA-- 270

  Fly   648 LSVIVVRFRHLGTDVDHLIR 667
               :...|:|..|:..||.|
  Rat   271 ---LAAGFQHKDTEYSHLTR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380
		LRR_8	205..266	CDD:290566
		leucine-rich repeat	210..230	CDD:275380
		leucine-rich repeat	232..255	CDD:275380
		LRR_RI	<256..410	CDD:238064
		leucine-rich repeat	256..276	CDD:275380
		LRR_8	279..359	CDD:290566
		leucine-rich repeat	280..303	CDD:275380
		leucine-rich repeat	304..348	CDD:275380
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085	28/136 (21%)
Npr3	XP_006232107.1	PBP1_NPR_C_like	165..556	CDD:107381	33/149 (22%)
		ANF_receptor	182..535	CDD:279440	30/144 (21%)
		TM_EphA1	587..618	CDD:214014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900