DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and SCRIB

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_874365.3 Gene:SCRIB / 23513 HGNCID:30377 Length:1655 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380
LRR_8 109..169 CDD:290566
leucine-rich repeat 111..135 CDD:275380
leucine-rich repeat 136..158 CDD:275380
leucine-rich repeat 159..183 CDD:275380
leucine-rich repeat 184..209 CDD:275380
LRR_8 205..266 CDD:290566
leucine-rich repeat 210..230 CDD:275380
leucine-rich repeat 232..255 CDD:275380
LRR_RI <256..410 CDD:238064
leucine-rich repeat 256..276 CDD:275380
LRR_8 279..359 CDD:290566
leucine-rich repeat 280..303 CDD:275380
leucine-rich repeat 304..348 CDD:275380
leucine-rich repeat 349..372 CDD:275380
PP2Cc 461..655 CDD:294085
SCRIBNP_874365.3 Sufficient for targeting to adherens junction and to inhibit cell proliferation 1..818
LRR_RI 12..232 CDD:238064
leucine-rich repeat 14..37 CDD:275380
leucine-rich repeat 38..60 CDD:275380
LRR 39..401 CDD:227223
leucine-rich repeat 61..83 CDD:275380
leucine-rich repeat 84..106 CDD:275380
leucine-rich repeat 107..129 CDD:275380
leucine-rich repeat 130..152 CDD:275380
leucine-rich repeat 153..175 CDD:275380
leucine-rich repeat 176..198 CDD:275380
leucine-rich repeat 199..221 CDD:275380
leucine-rich repeat 268..290 CDD:275380
leucine-rich repeat 291..313 CDD:275380
leucine-rich repeat 314..336 CDD:275380
leucine-rich repeat 360..381 CDD:275380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 417..440
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 459..604
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 633..702
Interaction with ARHGEF7. /evidence=ECO:0000269|PubMed:15182672 717..1229
PDZ 725..813 CDD:214570
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 827..853
PDZ_signaling 860..947 CDD:238492
PDZ_signaling 1002..1090 CDD:238492
PDZ_signaling 1098..1189 CDD:238492
Interaction with tick-borne encephalitis virus RNA-directed RNA polymerase NS5. /evidence=ECO:0000269|PubMed:18042258 1105..1117
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1227..1246
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1277..1489
AbLIM_anchor 1555..>1593 CDD:292800
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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