DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and lron-8

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_491676.2 Gene:lron-8 / 181983 WormBaseID:WBGene00020693 Length:341 Species:Caenorhabditis elegans


Alignment Length:278 Identity:66/278 - (23%)
Similarity:107/278 - (38%) Gaps:87/278 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   103 ELIINGTN-LQTLVADHNYLHNISTTNTHPVPLKL------QRIDISHNNFSELPNWVGACASLT 160
            |:...|.| |..|..|.:|| .:.|.|.|...|.|      ..|::||               ||
 Worm    28 EMTCRGKNSLHDLKKDQDYL-EVDTLNVHQAKLDLTDDLVPDGINLSH---------------LT 76

  Fly   161 AINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQ---LQSNELP-SLP 221
            .:||:.|::..:.                           ..||..||::|   |..|::. |.|
 Worm    77 LLNATDNQITRIG---------------------------RRGFDKIRNMQFLYLSINQISHSQP 114

  Fly   222 DNFFAVTH-ARLE---TLNVSCNKLSTLPR---YEQNNHAALVNLSLAGNHLNDSIFEPLHNAAK 279
            |.|.|:.. .|||   .|:.:..:.|.:.|   :.:|:...|..:.|..|.:.....:.......
 Worm   115 DPFQALEKLKRLEMNDALDGNMEEKSDMLRNFFHSKNSFVHLAQIELNKNKIEGIYPKTFCGIQG 179

  Fly   280 LRVLHLAYNRIGVLPAA--CVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQ 342
            |:.|.|:.|||.....|  |::   ||:.|:|:||::|::|.::...                  
 Worm   180 LQRLELSNNRIPSFDFARTCLK---ELKALMLAGNLIQKIPADIWDF------------------ 223

  Fly   343 LAKLAMLKVLDLSHNHLD 360
               |..|..||:|:|.:|
 Worm   224 ---LPSLSSLDISNNPID 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380 2/6 (33%)
LRR_8 109..169 CDD:290566 19/66 (29%)
leucine-rich repeat 111..135 CDD:275380 8/23 (35%)
leucine-rich repeat 136..158 CDD:275380 4/27 (15%)
leucine-rich repeat 159..183 CDD:275380 5/23 (22%)
leucine-rich repeat 184..209 CDD:275380 3/24 (13%)
LRR_8 205..266 CDD:290566 20/71 (28%)
leucine-rich repeat 210..230 CDD:275380 8/24 (33%)
leucine-rich repeat 232..255 CDD:275380 6/28 (21%)
LRR_RI <256..410 CDD:238064 26/107 (24%)
leucine-rich repeat 256..276 CDD:275380 3/19 (16%)
LRR_8 279..359 CDD:290566 22/81 (27%)
leucine-rich repeat 280..303 CDD:275380 8/24 (33%)
leucine-rich repeat 304..348 CDD:275380 8/43 (19%)
leucine-rich repeat 349..372 CDD:275380 6/12 (50%)
PP2Cc 461..655 CDD:294085
lron-8NP_491676.2 LRR <71..>237 CDD:227223 51/231 (22%)
leucine-rich repeat 75..98 CDD:275380 8/49 (16%)
leucine-rich repeat 99..122 CDD:275380 8/22 (36%)
leucine-rich repeat 123..158 CDD:275380 8/34 (24%)
leucine-rich repeat 159..179 CDD:275380 2/19 (11%)
leucine-rich repeat 180..202 CDD:275380 8/24 (33%)
leucine-rich repeat 203..226 CDD:275380 8/43 (19%)
LRRCT 235..282 CDD:214507 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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