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Protein Alignment Phlpp and AgaP_AGAP001985

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	XP_321074.5	Gene:	AgaP_AGAP001985 / 1281135	VectorBaseID:	AGAP001985	Length:	1009	Species:	Anopheles gambiae

Alignment Length:	983	Identity:	186/983 - (18%)
Similarity:	309/983 - (31%)	Gaps:	350/983 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 QLGGSILIGNYNYLT-QLEVCENEMEVLDLSSLAQLETLKCSRNKLMEL----IINGTNLQTLVA 116
            :|..|.|:|..|:.| ||........:..|:...:.:.|..|.:.|.|:    |:.|:::
Mosquito   163 ELVKSDLLGETNHYTFQLTFDNRAFSLATLAMTREEKHLPISASVLFEIFPFCIVFGSDM----- 222

  Fly   117 DHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINASH--NRLNNVAVLL--- 176
               .:.:|..:....:|..|.:         ::.:|......|.|.....  ||.||:..|:
Mosquito   223 ---VVRSIGNSLMVILPDLLSK---------KITDWFELRRPLIAFKFQTILNRTNNIFELVTVQ 275

  Fly   177 ------RNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETL 235
                  .|.|.||||           |.:..|.....|.|:|:...:  ..:|::.:..
Mosquito   276 SVKKRPENQRKTELV-----------LSEEEEEEEVERRLRLKGQMI--YMENWYMIMF------ 321

  Fly   236 NVSCNKLST--LPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGV-LPAAC 297
                  |.|  :|:        |.:|...|.::||.   .:|:.:  |.|.||..:..| |..|.
Mosquito   322 ------LGTPVMPK--------LTSLISTGLYINDL---SMHDFS--RDLMLAGTQQSVELKLAL 367

  Fly   298 --------------------VRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLC--- 339
                                :|...||        :.|.:|::||.    |:.|..|.:..|
Mosquito   368 DQEQQKSKKLEESMRKLDEEMRRTDEL--------LYQMIPKQVAD----RLRRGENPIDTCEMF 420

  Fly   340 --------------------TPQ--LAKL-AMLKVLD--LSHNHLDRVNLLALVPSRNLKYLDLS 379
                                ||.  ::.| ||..:.|  ...||:.:|..:...      |:.:|
Mosquito   421 NSVSILFSDVVTFTEICSRITPMEVVSMLNAMYSIFDTLTERNHVYKVETIGDA------YMVVS 479

  Fly   380 GNLQLQVDEQQF--KVCQSQSQRHWSLVDV----------------SGNNRAALPTTKIRQ---- 422
            |   ....||..  |||........::.|:                ||...|.:...|:.:
Mosquito   480 G---APAKEQNHAEKVCDMALDMIEAITDLKDPSTGTHLRIRVGVHSGAVVAGIVGLKMPRYCLF 541

  Fly   423 ---VSAQRNQNKTSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQ 484
               |:.......||....:..:|          |...|.:|||..|:..      .::.:|:...
Mosquito   542 GDSVNTASRMESTSQAMRIHISE----------STKHLLSANYRVSERG------EIDVKGKGTM 590

  Fly   485 EMSHL-----VPDLMKQEQMVKDSAVRDY------------MKFTLLAAQQQCGSVRSAAL---- 528
            :...|     .|.|...::.:|..|: :|            ..|:..|.:|..|.:.||.|
Mosquito   591 KTYWLDYRENRPPLQLLDEEIKTPAI-EYDPGKDRRVSIPSCMFSQPAHKQSLGGLSSAGLEDRR 654

  Fly   529 ------FHLTRTR----APSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIH 583
                  |.....|    :|.|:.....:....|..|||  .|::                    |
Mosquito   655 VYSPVTFEDVARRSIANSPVKLHAFGPRGRENRSNSTG--HAFM--------------------H 697

  Fly   584 SMPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIRKEENSLLAAKRLVDIAQSFAA---A 645
            |:.|  |...::::.:|:|          .|:...    ....|:|.:|........|..|   .
Mosquito   698 SVSD--VFGSLVNDTEEFL----------EDLQHR----NSISNTLYSASTPSPCPFSPPAQFRT 746

  Fly   646 ESLSVIVVRFRHLGTDVDHLI-----RELKQSVRKKPQPVSLPLSSGSVCKRTCCDRSNA--CRH 703
            :|.|....:|    .|.||.:     :.|.|.|.|||:        |.:.|....:...|  |.|
Mosquito   747 KSKSCYQAQF----MDKDHELLSGASKALLQEVPKKPK--------GILAKAQTVEHGPAAPCEH 799

  Fly   704 RAIEQEPLAGRSSPSGQSDRDLLAKDKDDEFVLAHARVLQEEQQLEMLDETESVSESVLSEEQFK 768
            :|..:                   |.|.|..         ::||.:.|::
Mosquito   800 KAKAR-------------------KAKLDAV---------KQQQTKALEK--------------- 821

  Fly   769 CWEYMLEQNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERNDFTSNLMRTVTNKFISTSTP 833
                 |:|..|.::|.:|.  ...|..    |....:...:.:.|..|....|:|    :..||.
Mosquito   822 -----LDQMVQEIYDADLP--GMCFVN----PPGSRSDGNICQSNSCTLGSSRSV----VDASTS 871

  Fly   834 QLPQPITTS----VPLGSYHQVKQAP-------PGHFGSALSFQQAHSYGYNLFDAKPRPKFHGG 887
            ......||:    ..|..|..|..:|       |.|.....:...:|     |...:|.|...|.
Mosquito   872 DTASTTTTACNALYTLNLYFPVSCSPGCACGLVPDHCSRPQAVPSSH-----LGTGQPGPSGSGL 931

  Fly   888 TVKRSAGP 895
            .|:..|||
Mosquito   932 PVQAGAGP 939

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.