Protein Alignment Phlpp and AgaP_AGAP000090

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: XP_311062.5
• Gene: AgaP_AGAP000090 / 1272181
• VectorBaseID: AGAP000090
• Length: 1641
• Species: Anopheles gambiae
• Alignment Length: 485
• Identity: 90/485 - (18%)
• Similarity: 159/485 - (32%)
• Gaps: 177/485 - (36%)

  Fly   562 LIRRTSQLRLTKPDVIQKDQIHSMPDPHVLELILSND---------DEYLVVGNAQLWSVMDIDR 617
            |:||  ||.:.|.  :::..||||..|.|.:|:|...         |:|...|..:. :..|:..
Mosquito   280 LVRR--QLEMEKQ--LKEKMIHSMMPPKVADLLLKESGSVPKGTSFDQYPAPGGRRT-TPSDLKS 339

  Fly   618 AAREI---RKEENSLLAA-----KRLVDIAQSFAAAESLSVIVVRFRHL----GTDVDHLIRELK 670
            ..|..   |.|..|:|.|     .|:.....:....|.|:.:..||..|    |.:....:.:..
Mosquito   340 LFRPFHMNRMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCLVNGCEKISTLGDCY 404

  Fly   671 QSVRKKPQPVSLPLSSGSVCKRTCCDRS----------NACRHRAIEQE---------------- 709
            ..|...|:    |....::|   |.:..          :|.|:..|:..
Mosquito   405 YCVSGCPE----PRPDHAIC---CVEMGLGMIESIRVFDAQRNEGIKMRVGVHTGTVLCGIVGTK 462

  Fly   710 -----------PLAGRSSPSGQSDRDLLAKDKDDEFVLAHARVLQEEQQLE----------MLDE 753
                       .||.|...||:.|:..::::...  .|..:.:::|.::::          .||.
Mosquito   463 RVKFDVWSNDVTLANRMESSGKPDQVHVSEETCG--FLGDSYIIEEGEEVDGHRTYFVLGKRLDL 525

  Fly   754 TESVSESVLSEEQFKCWEYMLEQNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERNDF--- 815
            ..|::|.:.|                :....:||.:..|            :.:.|.|..|:
Mosquito   526 VGSITEGLSS----------------IGLPVDLNLLGAS------------SPSPLDELRDYATS 562

  Fly   816 -----TSNLMRTVTNKFISTSTPQLPQPITTSVPLGSYHQVKQAPPGHFGSALSFQQAHSYGYNL 875
                 :|.|.|:.||  :|:..|.:| |.:.:.|:             |.|:|.....
Mosquito   563 EEHPESSCLSRSATN--LSSIQPAVP-PASPAGPV-------------FFSSLHASPV------- 604

  Fly   876 FDAKPRP---------KFHGGTVKRSAGPNSAYFGSLQRLM----------PYNFEYDFAVTQER 921
              :.|||         ||....|.:..|..        ||:          |...:....::.:.
Mosquito   605 --STPRPRIASLTKMTKFLRSAVSKGDGGG--------RLLNAGRTPPAPPPVVEKPKIIISTKS 659

  Fly   922 ERNILDEEEHDDDD-------FNEHESRMR 944
            ..|..|.::.||||       .||.:..:|
Mosquito   660 ISNGFDSDDDDDDDDRGGGGGCNEDDELVR 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380
		LRR_8	205..266	CDD:290566
		leucine-rich repeat	210..230	CDD:275380
		leucine-rich repeat	232..255	CDD:275380
		LRR_RI	<256..410	CDD:238064
		leucine-rich repeat	256..276	CDD:275380
		LRR_8	279..359	CDD:290566
		leucine-rich repeat	280..303	CDD:275380
		leucine-rich repeat	304..348	CDD:275380
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085	27/109 (25%)
AgaP_AGAP000090	XP_311062.5	CYCc	287..494	CDD:214485	40/216 (19%)
		Guanylate_cyc	346..520	CDD:278633	28/182 (15%)
		CYCc	1409..1604	CDD:214485
		Guanylate_cyc	1435..1625	CDD:278633

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900