Protein Alignment Phlpp and Gucy2f

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: NP_446283.1
• Gene: Gucy2f / 116556
• RGDID: 620439
• Length: 1108
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 85/421 - (20%)
• Similarity: 141/421 - (33%)
• Gaps: 116/421 - (27%)

  Fly   522 SVRSAA--LFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDV-------- 576
            |::|:|  :|.:.:......|.||....|...|.:.  :..:..||:.:..||:.||
  Rat   586 SIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAI--VSEFCSRRSLEDILTQDDVKLDWMFKS 648

  Fly   577 -IQKDQIHSMPDPHVLELILSN--------DDEY-LVVGNAQLWSVMDIDRAAREIRKEENSLLA 631
             :..|.|..|...|..|.|...        |..: |.|.:....:::::.|.:.|...||..|..
  Rat   649 SLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNNILEMLRLSEEEPSEEELLWT 713

  Fly   632 AKRLV-------------DIAQSFAAAESLSVIVVR---FRHLGTDVDHLIRELKQSVRKKPQPV 680
            |..|:             |: .|||..  :..::||   |..:......:|..||.     |.||
  Rat   714 APELLRAPGGIRLGSFAGDV-YSFAII--MQEVMVRGAPFCMMDLSAKEVIDRLKM-----PPPV 770

  Fly   681 SLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAG----------------------RSSPSGQSDR 723
            ..|:.|.......|......|...|.||.|...                      |......|:.
  Rat   771 YRPVVSPEFAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNL 835

  Fly   724 DLLAKDKDDEFVLAHARVLQEEQQLEML-------DETESVSESVLSEEQ--------------F 767
            :.|.:::.:|..:       |:|:.|.|       ...||:.:....|.:              |
  Rat   836 EDLIRERTEELEI-------EKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGF 893

  Fly   768 KCWEYMLE--------QNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERN---------DF 815
            .....|.|        .:...|||..:.  |....|..|:.:|.|.|:.||:||         :.
  Rat   894 TTISAMSEPIEVVDLLNDLYTLFDAIIG--SHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANM 956

  Fly   816 TSNLMRTVTNKFISTSTPQLPQPITTSVPLG 846
            :.:::.:| ..|.....|::|..|...:..|
  Rat   957 SLDILSSV-GTFKMRHMPEVPVRIRIGLHTG 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380
		LRR_8	205..266	CDD:290566
		leucine-rich repeat	210..230	CDD:275380
		leucine-rich repeat	232..255	CDD:275380
		LRR_RI	<256..410	CDD:238064
		leucine-rich repeat	256..276	CDD:275380
		LRR_8	279..359	CDD:290566
		leucine-rich repeat	280..303	CDD:275380
		leucine-rich repeat	304..348	CDD:275380
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085	37/168 (22%)
Gucy2f	NP_446283.1	PBP1_sensory_GC_DEF_like	54..435	CDD:107366
		ANF_receptor	75..412	CDD:279440
		PKc_like	545..815	CDD:304357	52/238 (22%)
		TyrKc	565..809	CDD:197581	52/232 (22%)
		HNOBA	<824..869	CDD:285003	9/51 (18%)
		CYCc	848..1040	CDD:214485	29/149 (19%)
		Guanylate_cyc	875..1062	CDD:278633	23/115 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900