Protein Alignment Phlpp and tlrs5

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: XP_002937550.2
• Gene: tlrs5 / 100489423
• XenbaseID: XB-GENE-22201327
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 124/576 - (21%)
• Similarity: 213/576 - (36%)
• Gaps: 164/576 - (28%)

  Fly    13 KSKLKVSASHSGPHPLPVEVTAAEEEQAATFGQ-------TSPQKLSLKGSQLGGSILIGNYNY- 69
            ||....:...:|.:.:|..:....:....:|.:       :.|..|.|:...||..:..|.::.
 Frog    34 KSHFVFNCLANGLYSIPSHIPPQTQSLLFSFNRIPSISQDSFPDLLHLQTLLLGSQVTPGTFSVG 98

  Fly    70 ---------LTQLEVCENEMEVLDL-----SSLAQLETLKCSRNKLMELIING------TNLQTL 114
                     |..|::..|  .:::|     ..|:.||.|....|.|.|.::..      |:|:.|
 Frog    99 KSAFRGFPNLITLDLGGN--RIINLHPEAFEGLSWLEVLLLDHNGLDESVLESGMFKDLTSLKKL 161

  Fly   115 VADHNYLHNISTTNTHPVPLKLQRID---ISHNNFS-----ELPNWVGACASLTAINAS------ 165
            ....|   ||......|..|||..|.   :..|..|     :|.|..|....|..::::
 Frog   162 DLSFN---NIRRVRPDPTFLKLSSISFLLLKFNKVSMLCGEDLQNLQGRRLQLLDMSSNPLQLSS 223

  Fly   166 --H--NRLNNV-------------AVLLRNY--------------RITELVSLDLAYNDLKQLDQ 199
              |  |..||:             |.::.|:              |.|..:.....:::||  |.
 Frog   224 TPHCTNPFNNITLGTLDVSSMGWNAEMVENFVRTISGTQVDYIKMRHTAGLGSGFGFHNLK--DP 286

  Fly   200 FPEGFSSIRSLQLQSNELPS------LPDNFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVN 258
            ..:.||.:.|..:|..:|.:      :|..|.|  ..:|.:|::|.|:::.:.....:....||:
 Frog   287 NKDTFSGLNSSNVQILDLSNGFISHLVPQLFSA--FPKLLSLDLSSNQINRMSSGAFSGLGELVS 349

  Fly   259 LSLAGNHLND---SIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPE- 319
            |:|:||.|.:   |.|:.| .|..|:.|.|:.|.||.:....:.::..|..|.|..|.|.::|.
 Frog   350 LNLSGNLLGELMGSSFQGL-GATSLKTLDLSSNHIGAVQYGALDSFTALTSLNLRDNALNKIPPT 413

  Fly   320 -----EVATLGQLRVLRCCNNLLLCTPQLAKLAMLKVLDLSHNHL-DRVNLLALVPSRNLKYLDL 378
                 ....|.|.|:....|.:..| |...      :||||.|.| |..:|..::..::||||.|
 Frog   414 KLQGVTFVLLKQNRISDIYNIISFC-PHAT------ILDLSSNRLTDFRSLWQILELQSLKYLSL 471

  Fly   379 SGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNNRAALPTTKIRQVSAQRNQNKTSGPWTMGFAET 443
            :.|                     ||.      |.:||.|.        |..:|||...:..::.
 Frog   472 ASN---------------------SLY------RCSLPHTS--------NITRTSGLVYLDLSDN 501

  Fly   444 P-----GSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQEMSHLVPDLM 494
            .     .||:|..:.::                 ..:|:....|..::|: :||.|
 Frog   502 ALGPVLKSGECGDIFMH-----------------LGSLKSLNLARNQLSN-IPDTM 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	6/24 (25%)
		LRR_8	109..169	CDD:290566	19/77 (25%)
		leucine-rich repeat	111..135	CDD:275380	6/23 (26%)
		leucine-rich repeat	136..158	CDD:275380	7/29 (24%)
		leucine-rich repeat	159..183	CDD:275380	8/60 (13%)
		leucine-rich repeat	184..209	CDD:275380	5/24 (21%)
		LRR_8	205..266	CDD:290566	17/66 (26%)
		leucine-rich repeat	210..230	CDD:275380	5/25 (20%)
		leucine-rich repeat	232..255	CDD:275380	4/22 (18%)
		LRR_RI	<256..410	CDD:238064	45/163 (28%)
		leucine-rich repeat	256..276	CDD:275380	10/22 (45%)
		LRR_8	279..359	CDD:290566	23/85 (27%)
		leucine-rich repeat	280..303	CDD:275380	6/22 (27%)
		leucine-rich repeat	304..348	CDD:275380	12/49 (24%)
		leucine-rich repeat	349..372	CDD:275380	8/23 (35%)
		PP2Cc	461..655	CDD:294085	6/34 (18%)
tlrs5	XP_002937550.2	PLN00113	100..>597	CDD:215061	113/510 (22%)
		leucine-rich repeat	108..131	CDD:275380	5/24 (21%)
		leucine-rich repeat	132..157	CDD:275380	6/24 (25%)
		leucine-rich repeat	158..182	CDD:275380	9/26 (35%)
		leucine-rich repeat	183..208	CDD:275380	6/24 (25%)
		leucine-rich repeat	209..232	CDD:275380	3/22 (14%)
		leucine-rich repeat	299..322	CDD:275380	5/24 (21%)
		leucine-rich repeat	323..346	CDD:275380	4/22 (18%)
		leucine-rich repeat	347..372	CDD:275380	11/25 (44%)
		leucine-rich repeat	373..396	CDD:275380	6/22 (27%)
		leucine-rich repeat	397..440	CDD:275380	11/43 (26%)
		leucine-rich repeat	418..431	CDD:275378	3/12 (25%)
		leucine-rich repeat	441..492	CDD:275380	22/91 (24%)
		leucine-rich repeat	493..521	CDD:275380	3/44 (7%)
		leucine-rich repeat	522..545	CDD:275380	6/19 (32%)
		leucine-rich repeat	546..569	CDD:275380
		leucine-rich repeat	570..591	CDD:275380

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910