Protein Alignment Phlpp and lrrc2

DIOPT Version :9

• Sequence 1: NP_001260558.1
• Gene: Phlpp / 35178
• FlyBaseID: FBgn0032749
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: XP_002940651.1
• Gene: lrrc2 / 100486200
• XenbaseID: XB-GENE-962135
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 386
• Identity: 87/386 - (22%)
• Similarity: 158/386 - (40%)
• Gaps: 90/386 - (23%)

  Fly    74 EVCENEMEVLDLSSLAQLE-----TLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVP 133
            |.|:.|.|.|:.|:|.::.     .|:|..|.:.:.:              ||.|........:.
 Frog    26 ERCKKEEERLETSALEKIRQEWSFMLECRNNGIPQSV--------------YLKNGFVDTELKIL 76

  Fly   134 LKLQRIDISH-------------------NNFSELPNWVGACASLTAINASHNRLNNVAVLLRNY 179
            .|::|  .||                   .::.|||:.:.....|..::.::.|:..:...::.:
 Frog    77 EKIER--KSHIGRKEKSDKEDKYIYKLYGEHWEELPDSLREQTHLKQLHVNNTRIQTIPDYIQLF 139

  Fly   180 RITELVSLDLAYNDLKQLDQFPE-GFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVSCNKLS 243
            :  :|:.|||::|.::.|.  || |:.                        |.|:..|:|.|.|.
 Frog   140 Q--KLIVLDLSHNKIRCLP--PEIGYL------------------------ANLKEFNISFNNLQ 176

  Fly   244 TLPRYEQNNHAALVNLSLAGN-HLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEIL 307
            .:|. |..|...|..|.|:|| .|.:..|| |.:..|:..:.::.|:...:| .||.....|:.|
 Frog   177 IIPP-ELGNCENLEKLDLSGNLELTELPFE-LSSLKKVTFVDVSANKFSSIP-ICVLRMSSLQWL 238

  Fly   308 VLSGNMLQQLPEEVATLGQLRVLRC-CNNLLLCTPQLAKLAMLKVLDLSHNHLDRVNLLALVPSR 371
            .:|.|.||.||:::..|.:|..|.. .|.:...:.::..|..||:|.:|...|..:. .||..:.
 Frog   239 DISSNKLQDLPQDIDRLEELETLMLQKNKITYLSAEITNLTKLKLLVVSGESLVEIP-SALEENP 302

  Fly   372 NLKYLDL-----SGNLQLQVDEQQFKVCQSQSQRHWS-------LVDVSGNNRAALPTTKI 420
            :|||:.|     ..|:.|...|::.   .:|.|.::.       :.|::........|||:
 Frog   303 SLKYIKLLDNPIETNVCLDAKEERE---STQDQEYFEKEFMKAYIEDLTERETTPRYTTKV 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	3/23 (13%)
		LRR_8	109..169	CDD:290566	11/78 (14%)
		leucine-rich repeat	111..135	CDD:275380	3/23 (13%)
		leucine-rich repeat	136..158	CDD:275380	6/40 (15%)
		leucine-rich repeat	159..183	CDD:275380	2/23 (9%)
		leucine-rich repeat	184..209	CDD:275380	9/25 (36%)
		LRR_8	205..266	CDD:290566	14/61 (23%)
		leucine-rich repeat	210..230	CDD:275380	0/19 (0%)
		leucine-rich repeat	232..255	CDD:275380	8/22 (36%)
		LRR_RI	<256..410	CDD:238064	44/167 (26%)
		leucine-rich repeat	256..276	CDD:275380	9/20 (45%)
		LRR_8	279..359	CDD:290566	22/80 (28%)
		leucine-rich repeat	280..303	CDD:275380	4/22 (18%)
		leucine-rich repeat	304..348	CDD:275380	13/44 (30%)
		leucine-rich repeat	349..372	CDD:275380	7/22 (32%)
		PP2Cc	461..655	CDD:294085
lrrc2	XP_002940651.1	LRR	103..>314	CDD:227223	61/242 (25%)
		leucine-rich repeat	119..141	CDD:275380	2/23 (9%)
		leucine-rich repeat	142..164	CDD:275380	9/47 (19%)
		leucine-rich repeat	165..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..211	CDD:275380	9/23 (39%)
		leucine-rich repeat	212..234	CDD:275380	4/22 (18%)
		leucine-rich repeat	235..257	CDD:275380	9/21 (43%)
		leucine-rich repeat	258..280	CDD:275380	4/21 (19%)
		leucine-rich repeat	281..303	CDD:275380	7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45752
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100