Protein Alignment CG10492 and ZCCHC14

DIOPT Version :9

• Sequence 1: NP_001097179.1
• Gene: CG10492 / 35177
• FlyBaseID: FBgn0032748
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_055959.2
• Gene: ZCCHC14 / 23174
• HGNCID: 24134
• Length: 1086
• Species: Homo sapiens
• Alignment Length: 1179
• Identity: 232/1179 - (19%)
• Similarity: 364/1179 - (30%)
• Gaps: 503/1179 - (42%)

  Fly     4 KQDVLQWFEKLESYNRIETMYALLTACLPFELRFLGTLLEEQGRCDSETLRGMELRANNPHELAA 68
            :..|.:||.:|.|..|:|.:..||..|:|.||||||:.||:..|.|..:||..|::||||.:|.:
Human    10 RDGVYRWFSELPSPQRVEFLCGLLDLCIPLELRFLGSCLEDLARKDYHSLRDSEIKANNPADLGS 74

  Fly    69 DMVNCQKGDPTDRKIRRKMALYLALIRACNRNCVSEIYRTL-------ECWGECDFSCINDQDTL 126
             :.|.     ||..:|.|:.:.|||:.:..|.....:||||       ..:|    ..:|:..|.
Human    75 -LTNL-----TDEVVRSKLLVSLALLGSEQREAAGVLYRTLTHIDSIIHNYG----LQLNEGRTG 129

  Fly   127 LELLLVYTMAAIHPVFSMEEQKKIFGILAKIKENKLVAERFAPQMQRQTQTPVLQH--------- 182
            .|.||::|||:.||.||..::                      |:.||..|.:...
Human   130 DEFLLLFTMASNHPAFSFHQK----------------------QVLRQELTQIQSSLNGGGGHGG 172

  Fly   183 ---PHP-------PSPHDLVIQQQPP--HVIHQIPGPQQAPPH------PQHP------------ 217
               |.|       |:.|.:..:.:.|  .|.:.:........|      |:.|
Human   173 KGAPGPGGALPTCPACHKITPRTEAPVSSVSNSLENALHTSAHSTEESLPKRPLGKHSKVSVEKI 237

  Fly   218 -------------------------QMVQVLQTPQ------GNIPMIFP-QHFQKLLPSSDGTHQ 250
                                     .:..|.::..      ..:..::| ::.:||:|...|...
Human   238 DLKGLSHTKNDRNVECSFEVLWSDSSITSVTKSSSEVTEFISKLCQLYPEENLEKLIPCLAGPDA 302

  Fly   251 ISVD--------GMPHLMQPNITIPADTSAIISHQNTGWTMRHYV--PQPPHQ-------QPALQ 298
            ..|:        |:.:|           :::.||......:|.::  ..||.|       .|:|.
Human   303 FYVERNHVDLDSGLRYL-----------ASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLS 356

  Fly   299 Q--------------------QQPQSLDHQVPPASS----PMLSQQSSPSSSRTTSPQRDRSLIN 339
            :                    .|..:..|...||.|    |..|...|..|:.....|.|.|...
Human   357 KVGTVMGVSGRPVCGVAGIPSSQSGAQHHGQHPAGSAAPLPHCSHAGSAGSALAYRTQMDTSPAI 421

  Fly   340 VPLQAQQQPHQQQQ-----------------------------------------MRGMSQRMAD 363
            :...:.|.|..|:|                                         ..|..:::..
Human   422 LMPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKKKLKT 486

  Fly   364 Q------KNTRR---PSAE--------TTPPPTSIGG-----------------EQQHDSV-NEG 393
            |      |:.||   |||.        ...||||..|                 ||.|..: .||
Human   487 QLELEKEKSERRCLNPSAPPLVTSSGVARVPPTSHVGPVQSGRGSHAAELRVEVEQPHHQLPREG 551

  Fly   394 GSSNSSGTSLHRLIRNGFPRLGHNHRVKANTFIPQHQQQQQQH--------------HF------ 438
            .||..|.:|       ..| :|...|.:::....::.::.:.|              ||
Human   552 SSSEYSSSS-------SSP-MGVQAREESSDSAEENDRRVEIHLESSDKEKPVMLLNHFTSSSAR 608

  Fly   439 -------------QNPNYNMNV---------------MMQSMNINDDGSGSM---MNSMNSTKSA 472
                         .||:.:..:               |:.|::..:.||..|   .:|::|..|.
Human   609 PTAQVLPVQNEASSNPSGHHPLPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSL 673

  Fly   473 ATTGSESG---------SSNGSCGDLSPSETP-TPTQLSLPLHNSVDAGMGMITTVLPTGLGNYQ 527
            ......||         |...:..|:.|:..| .|.|        |.:|:...:::.||.....:
Human   674 EERNKGSGPRSSMKVDKSFGSAMMDVLPASAPHQPVQ--------VLSGLSESSSMSPTVSFGPR 730

  Fly   528 PKPHHFSYKQQQQQMNLQQRLNGRNGMDKTYQQ--------VYTTGTPSIV-------------S 571
            .|..|.|        .|.:.|       ||.||        ...|||||.|             |
Human   731 TKVVHAS--------TLDRVL-------KTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSS 780

  Fly   572 DAQTISSASLQQQQPQTLLIS------------------------------------------QS 594
            .....|:.|.|...|..:.||                                          .|
Human   781 SVPADSAISGQTSCPNNVQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSNTAS 845

  Fly   595 PVSTPTTT---VLLQPQQPPPTT------------YNTS------------------YPYHQRGP 626
            |.|.|:|:   :...|..|.|::            |::|                  :.:||:.|
Human   846 PSSHPSTSFANMATLPSCPAPSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPP 910

  Fly   627 PPPQQTIFQAHSAPPPQ---------------------TVRGGFRYPMGPP-------------- 656
            .|||       .||||.                     :....|::|...|
Human   911 APPQ-------PAPPPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTFPFLPFSPMC 968

  Fly   657 ---------HNGELIYPTFHTSLAFLPMTAGGTPTAVTPAQLQSTAAVVSTNAVSVQTVPTPQQQ 712
                     :.|...:|..|.     |.::.|||..|...  |||.||.........|....|.|
Human   969 SSGYVSAQQYGGGSTFPVVHA-----PYSSSGTPDPVLSG--QSTFAVPPMQNFMAGTAGVYQTQ 1026

  Fly   713 QVPSTTPYSALTVCPITGAGGGGTAPKV--ISCYNCGSQTHSGRECQEASMEDVTRSASYKLDYS 775
                          .:.|:..|.:..|.  :||||||:..|..::|::.|| |..|..:::|.|:
Human  1027 --------------GLVGSSNGSSHKKSGNLSCYNCGATGHRAQDCKQPSM-DFNRPGTFRLKYA 1076

  Fly   776 --ETSMDSS 782
              ..|:||:
Human  1077 PPAESLDST 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10492	NP_001097179.1	PAT1	<164..>268	CDD:286811	22/182 (12%)
		PHA03247	<591..702	CDD:223021	38/229 (17%)
ZCCHC14	NP_055959.2	PX_domain	256..339	CDD:383026	12/93 (13%)
		SAM_ZCCH14	431..495	CDD:188957	4/63 (6%)
		zf-CCHC	1045..1060	CDD:365871	7/14 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152089
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003742
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109698
Panther	1	1.100	-	-	LDO	PTHR16195
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930