Protein Alignment CG10492 and Zcchc2

DIOPT Version :9

• Sequence 1: NP_001097179.1
• Gene: CG10492 / 35177
• FlyBaseID: FBgn0032748
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_006529575.1
• Gene: Zcchc2 / 227449
• MGIID: 2444114
• Length: 1171
• Species: Mus musculus
• Alignment Length: 1162
• Identity: 221/1162 - (19%)
• Similarity: 372/1162 - (32%)
• Gaps: 465/1162 - (40%)

  Fly     4 KQDVLQWFE-KLESYNRIETMYALLTACLPFELRFLGTLLEEQGRCDSETLRGMELRAN---NPH 64
            ::.|.:||. .|.|..|:|.|..||..|.|.||||||:.||:..|.|...||..|.:||   :|.
Mouse    91 QERVYEWFGLVLGSAQRLEFMCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPG 155

  Fly    65 ELAADMVNCQKGDPTDRKIRRKMALYLALIRACNRNCVSEIYRTL-------------------- 109
            .||         |..:..:|.::.:||||:.:.||.....::|.|
Mouse   156 SLA---------DFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDAVLRSLRATRAEGSRG 211

  Fly   110 ----ECWGECDFSCIND----------------------QDTLLELLLVYTMAAIHPVFSMEEQK 148
                |..|:.:.....|                      |:   ||||::|||::||.||..::.
Mouse   212 SVEDEPSGDGEQDAEKDGPGPEGSGCAKLGTGGGLGFRAQE---ELLLLFTMASLHPAFSFHQRV 273

  Fly   149 KIFGILAKIKENKLVAERFAPQ----------------------MQRQTQTPVLQHPHPPSPHDL 191
            .:...|.:::.    |.|..|:                      ..:..:|.:::....| |..|
Mouse   274 TLREHLERLRS----ALRVEPEDAEVEPSNFAGSRAQNDSACGDYIQSNETGLVEQAQIP-PDGL 333

  Fly   192 VIQQQPPHVIHQIPGPQQAPPHPQHPQMVQVLQTPQGNIPMIFPQHFQKLLPSSD-------GTH 249
            .:            .|.:|.....|.:.:.:....:......:...|:  :..||       .||
Mouse   334 TV------------APHRAQREAVHIEKIMLKGVQRKRADKYWEYTFK--VNWSDLSVTTVTKTH 384

  Fly   250 QISVDGMPHLMQPNITIPADTSA------IISHQNTGWTMRHYVPQPPHQQPALQQ---QQPQSL 305
            |       .|.:..:.:|.:.|:      |:...|.| ::|....:.|..:|.|:|   ..||:.
Mouse   385 Q-------ELQEFLLKLPKEFSSESFDKTILKALNQG-SLRREERRHPDLEPILRQLFSTSPQAF 441

  Fly   306 --DHQVPPASSPMLSQQSSPSSSRTTSPQRDRSLINVPLQAQQQPHQQQQMRGMSQRMADQKNTR 368
              .|:|......:.|:.....::..:|.:..:.|.::...:.:...|::.:  :...:..:|:..
Mouse   442 LQSHKVRSFFRSISSESQHNFNNLQSSLKTSKILEHLKEDSSEASSQEEDV--LQHTIIHKKHAG 504

  Fly   369 RPSAETTPPPTSIGGEQQHDSVNEGGS-SNSSGTSLHRLIRNGF--------PRLGHNHRVKANT 424
            :..|                 :|...| |...|.::....:||.        ..:.|:....::.
Mouse   505 KSPA-----------------LNVATSCSPLDGLTMQYAEQNGIVDWRNQGCAAIQHSEHCVSSA 552

  Fly   425 FIPQHQQQQQQHHFQNPNYNM-NVMMQSMNINDDGSGSMMNSMNSTKSAATTGS----------- 477
              .||..:::.....|..... .|..:.:...:|...|.:|.:..:......||
Mouse   553 --DQHSAEKRSLSSGNKKKGKPQVEKEKVKKTEDRLNSRINGIRLSAPQHVHGSTVKELLFLDMN 615

  Fly   478 -ESGSSNGSCGDLSPSETPTPTQLSLPLH------------------NSVD---------AGMGM 514
             :.||.:.:||:.|.....:|   |.|.|                  ||.|         :|.|.
Mouse   616 LDIGSGHDTCGETSSESYSSP---SSPRHDGRESLESEEEKDRDSDSNSEDSVNPSSARFSGYGS 677

  Fly   515 I-----------TTVLPTGLGN---------------YQPKPH---HFSYKQQQQQMNLQQRLNG 550
            :           |..|.|..||               :.|..|   |...::.|..:...:..:|
Mouse   678 VAQTIAVKPPAETVSLGTEDGNLLEAALTSHKYPHIPFMPTLHCVTHNGAQKSQVVIPSPKSADG 742

  Fly   551 RN-GMDKTYQQVYTTGTPSIVSDAQTIS----------------SASLQQQQPQTLLISQSPVST 598
            :. ||              :|.:|..||                :||.:.::...||  .||:..
Mouse   743 KTLGM--------------LVPNAVAISAVMESSNSAPVGILGPAASGESEKHLELL--ASPLPL 791

  Fly   599 PTT---------------TVLLQPQQ-----------PPPT------TYNTSY-PYHQRGPPP-- 628
            |:|               ::.|||.|           |.||      :.||:: |.|..|..|
Mouse   792 PSTFLPHSSAPALQLTLQSLKLQPPQGSSDSCPVSIPPQPTGSLSIGSPNTAFIPVHNPGSFPGS 856

  Fly   629 ------------PQ-----QTIFQAH----SAPPPQTVR--------------GGFRYPMGPPHN 658
                        ||     |.:.|..    :.|.|..|:              ..|.:|..|...
Mouse   857 PVATTDPITKSAPQVVGLNQMVPQIEGNTGTVPQPSNVKVVLPAAGLSAAQPPASFPFPGSPQAA 921

  Fly   659 GELIYPTFHTS-----LAFLPMTAGGTPTAVT-----------------PAQLQSTAAVVSTNAV 701
            ..|  ||.::|     .:..|.:.|.:|:..|                 ||...|||...||:.:
Mouse   922 SAL--PTQNSSALNAATSAQPASTGISPSQSTVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYI 984

  Fly   702 SV-------QTVPTPQQQ----------------------------------QVPS--------- 716
            |.       .|:..|||.                                  ::||
Mouse   985 SAVGNTNANGTIVPPQQMGPCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYRLPSFFTLPSICN 1049

  Fly   717 --------------------TTPY-SALTVCPITG----------AGGG---------------- 734
                                .||| :.|...|:.|          ||.|
Mouse  1050 GSYLNQAHQSNGNQLPFFLPQTPYANGLVHDPVMGSQASYGMQQMAGFGRLYPVYPAPNVVANTS 1114

  Fly   735 GTAPKV---ISCYNCGSQTHSGRECQEASMEDVTRSASYKLDY------SETSMDSS 782
            |:.||.   :||||||...|..::|:::||| ..:..:|:|.|      |..::||:
Mouse  1115 GSGPKKNGNVSCYNCGVSGHYAQDCKQSSME-ANQQGTYRLRYAPPLPPSNDTLDSA 1170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10492	NP_001097179.1	PAT1	<164..>268	CDD:286811	17/132 (13%)
		PHA03247	<591..702	CDD:223021	42/202 (21%)
Zcchc2	XP_006529575.1	PX_domain	341..>433	CDD:383026	17/101 (17%)
		DUF5585	<657..944	CDD:375359	57/304 (19%)
		PHA03247	<813..960	CDD:223021	31/148 (21%)
		zf-CCHC	1126..1141	CDD:365871	7/14 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842166
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12645
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003742
OrthoInspector	1	1.000	-	-		oto92547
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5470
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910