DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10492 and gls-1

DIOPT Version :9

Sequence 1:	NP_001097179.1	Gene:	CG10492 / 35177	FlyBaseID:	FBgn0032748	Length:	810	Species:	Drosophila melanogaster
Sequence 2:	NP_871882.2	Gene:	gls-1 / 172682	WormBaseID:	WBGene00007975	Length:	1052	Species:	Caenorhabditis elegans

Alignment Length:	567	Identity:	109/567 - (19%)
Similarity:	178/567 - (31%)	Gaps:	221/567 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 LSQQSSPSSSRTTSPQRDRSLINVPLQAQQQPHQQQQ------MRGMSQRMADQKNTRRPSAETT 375
            |:.|.....||.|.       |.:...|.::.|||::      |.|        .|....:|.||
Worm    26 LTLQEKRKKSRLTG-------ILMKSMANKKNHQQKKSTDGSTMNG--------NNATATAAATT 75

  Fly   376 PPPTSIG--GEQQHDSVNEGGSSNSSGTSLHRLIRNGFPRLGHNHRVKANTFIPQHQQQQQQHHF 438
            ...:.||  ....|...|:..|||::.||...:          .......|.:|..||.|.|:.:
Worm    76 QNSSQIGQNSNSSHSVTNDNTSSNNASTSTSSI----------TSTTTTTTTVPSSQQSQSQNQY 130

  Fly   439 QNPNYNMNVMMQSMNINDDGSGSMMNSMNS-----------TKSAATTGSESGSSNGSCGDLSPS 492
            .:           ..::...|.|....::.           .|::.|..|:||:..|:.....|.
Worm   131 SH-----------QRLSSTSSTSQQTGISKFPAKKAGHNELEKTSNTANSQSGAFKGTTNKDRPK 184

  Fly   493 ETPTPTQLSLPLHNSVDAGMGMITTVLPTGLGNYQPKPHHFSYKQQQQQMNLQQRLN-GRNGMDK 556
            |....|      |:                 ||.|.:.:|..:.......|.|.|.| .|:..::
Worm   185 EKEKNT------HS-----------------GNRQSQVNHNHHHSNHVSGNQQNRKNKNRDHSNQ 226

  Fly   557 TYQQVYTTGTPSI--VSDAQT---ISSASLQQQQPQTLLISQSPVS-TPTTTVLLQPQQ-----P 610
            :|:..||....:.  :.:|::   :|::|| ....|....|..||| |||...:.|..:     |
Worm   227 SYRGGYTHNHNNYHSLENAKSSGFLSNSSL-SSAGQISASSAPPVSTTPTAIPIFQESKIVQTDP 290

  Fly   611 P------------------PTTYNTSYP------------------------------------- 620
            |                  |..|.::.|
Worm   291 PVEEAKKKKEKPKIKRDEEPMPYKSTDPKNMDSVMAFKEHDEWDKVEFMCELVSFLSPTDLRLLG 355

  Fly   621 ---------YHQR-----------------------GPPPPQQ----------TIFQAHSAPPPQ 643
                     |:.:                       .||||||          .::|..:|....
Worm   356 NCIEGSVRCYNNQMRPVEKTSNCSDPTAGLPQFVCSPPPPPQQVYYFPGIADAALYQTRNAVNSV 420

  Fly   644 TVRGGFRYPMG-PPHNG---ELIYP---TFHTSLAFLPMTAGGTPTAVTPAQLQSTAAVVST--N 699
            .|:   ::|.| ||..|   .::||   .||.|.:   .|...:..:|....:.:...|:|:  |
Worm   421 FVQ---QHPPGLPPLLGGMQNIMYPPDANFHHSTS---CTTPSSSVSVANKDVNNVPVVLSSSVN 479

  Fly   700 AVSVQTVPTPQQQQVPSTTPYSALTVCPITGAGGGG-------TAPK 739
            .:| ..:|:.:||          |...|.|..|..|       |:|:
Worm   480 GIS-NNIPSDRQQ----------LDSKPNTARGSSGNINQSNTTSPE 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10492	NP_001097179.1	PAT1	<164..>268	CDD:286811
CG10492	NP_001097179.1	PHA03247	<591..702	CDD:223021	38/222 (17%)
gls-1	NP_871882.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930