Protein Alignment Acn and Acin1

DIOPT Version :10

• Sequence 1: NP_609935.1
• Gene: Acn / 35173
• FlyBaseID: FBgn0263198
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_063130304.1
• Gene: Acin1 / 305884
• RGDID: 1311945
• Length: 1391
• Species: Rattus norvegicus
• Alignment Length: 856
• Identity: 253/856 - (29%)
• Similarity: 384/856 - (44%)
• Gaps: 215/856 - (25%)

  Fly    17 PVAVARRSRRSRKVSENEKTEVETPVVAQNNEAECPKVPPASQEINEAR--ASSEERAGSGASPV 79
            |.|.:..||.|...|.:.::...:|..:.:.....|:  ...:|:::||  |:..:||..|:...
  Rat   573 PSADSSSSRSSSPSSSSSRSRSRSPDSSASRSQSSPR--SKQREVSQARVHANPHDRAKMGSRST 635

  Fly    80 RRSRGSRTTPRKRTESKGGDKKVD---------TIPE-EEPENGKDVEKDAVE-----EEKTVAP 129
            ..|| ||:..|.|:.|.|..|.:.         |..| ::|..|::....:|.     |.|..||
  Rat   636 SESR-SRSRSRSRSASSGSRKSLSPGVSRDGNTTYTETKDPSCGQEAAAPSVPQLQVLEPKEKAP 699

  Fly   130 PAA------NESESEDRAKTEDQQAQDDE----SC----AEPAVVKDDDVEKEDLK--PQQE-VP 177
            ..:      :.|:.|...|...|:.|.::    .|    |||.........:..|.  |:.| .|
  Rat   700 TCSASVRGRHMSQPEPEQKHVIQRLQPEQESPKKCEAEEAEPPAATQPQTSEPQLSQLPEAERTP 764

  Fly   178 TSTDD------DTKQSEPEQEVKVPSPSSKDEEHLKTTSDVLDIQTEEVDERDEEASAPAERRET 236
            .:.::      ||.::.||.||..|.....|:     .|:         |:|.|.:
  Rat   765 HTAEEKEDVTMDTSENRPENEVPEPPVPIADQ-----VSN---------DDRPEGS--------- 806

  Fly   237 KKRHKEQIKEQQPAEEEEHKENHKQIDENPEQIHDEPADLSNDKHDPCLNSSATNTTGAPVLQQQ 301
                         |||||.||:     ..|:....:.:.:|..|.....||   :|.|.
  Rat   807 -------------AEEEERKES-----SMPKSFKRKISVVSATKGVQAGNS---DTEGG------ 844

  Fly   302 RSVRKRKWLTNKKSSDRTPPVLAISTDSLKNIIADVVQPVPLS------DVQLESS--SEEEGLV 358
            :..|||:|..:..::.:.|.: :|:|:|||::|.|:   .||:      |:..:.|  ||:|
  Rat   845 QPGRKRRWGASTAATQKKPSI-SITTESLKSLIPDI---KPLAGQEAVVDLHADDSRISEDE--- 902

  Fly   359 TSDRDSE-----------RSASPAPPSEASKDRDNKGNTANTCDTTAEASADNEGAGAAPPAAA- 411
             ::|:.:           |:.:...|:|..::...:          .|...:.|....|||.|:
  Rat   903 -TERNGDDGTHDKGLKICRTVTQVVPAEGQENGQRE----------EEEEKEPEAEPPAPPQASV 956

  Fly   412 ------------------DTVSAQ-VSLSKATVSTAAPHIVRD---PSPARNRASHVLYITNLVR 454
                              ||::.: :|..|:.||......||.   |||.|.:.|::::|:||||
  Rat   957 EAALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVR 1021

  Fly   455 PFTVLQLKGLLARTGKIVEEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVD 519
            |||:.|||.||.|||.:||| .||||:|||.|:|.|||.:||:.||.|||||:||.||||.|..|
  Rat  1022 PFTLGQLKELLGRTGTLVEE-AFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCAD 1085

  Fly   520 FGSRTDMDRA----------------ILSTKDEAPRY-GQENTRDNQQ---SGNAWSRLE----- 559
            :..:.::.|.                .||.....|.| |..:...|..   |.:.:.:|:
  Rat  1086 YAEQDEVRRLRRGGGWMGQGGQHRSWDLSHPQVPPLYPGLASLVGNDVIHISLSLYPQLDYHRGL 1150

  Fly   560 ----PSDKK-------------PARPVREWDVGKKEPSDHDKHSNDRRRDSKDRLDSRSRDAERA 607
                ||:.|             |..||:.....:.||.:.::...::..:.:..::.|    ||.
  Rat  1151 LVDRPSEAKTEEQGAPRPLHPPPPPPVQPPPHPRAEPREQERAVREQWAEREREMERR----ERT 1211

  Fly   608 GQERKRSRD--REG---RGRDRERERLDRNAHARSRSGSPASKTKKENEPPIRLLDDLFRKTKGT 667
            ..||:..||  |||   |.|.|:|.|.:|   |:|:......|.|.:.|||.:||||||||||..
  Rat  1212 RSEREWDRDKVREGPRSRSRSRDRRRKER---AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAA 1273

  Fly   668 PCIYWLPLTPEAIAEKEAFRQKRIEEHKLRIKERE-----ERQKEREKDRDRQ--RETRRNRSNE 725
            |||||||||...|.:|||.:.:|.:|.:.|.||||     ||:||.|::|:||  ||.||..|.|
  Rat  1274 PCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEEEQKEREKEAERERNRQLEREKRREHSRE 1338

  Fly   726 RRRSRSRERER 736
            |.|.|.|||:|
  Rat  1339 RERDRERERDR 1349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acn	NP_609935.1	PTZ00121	<50..>251	CDD:173412	51/240 (21%)
		RRM_ACINU	444..530	CDD:409866	50/101 (50%)
		RSB_motif	599..693	CDD:465085	47/98 (48%)
Acin1	XP_063130304.1	None