Protein Alignment Acn and Acn

DIOPT Version :10

• Sequence 1: NP_609935.1
• Gene: Acn / 35173
• FlyBaseID: FBgn0263198
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_061518950.1
• Gene: Acn / 1280192
• VectorBaseID: AGAMI1_009083
• Length: 1003
• Species: Anopheles gambiae
• Alignment Length: 889
• Identity: 331/889 - (37%)
• Similarity: 448/889 - (50%)
• Gaps: 200/889 - (22%)

  Fly     5 SERKKSSSPAPVPVAVARRSRRSRKVSENEKTEVETPVVAQNNEAECPKVPPASQEINEARASSE 69
            |.|||..:|   |....|.|||.::  ..|||.|...|  :.|.||........:|..:.:...:
Mosquito   149 SRRKKEETP---PARTRRNSRREKE--SQEKTIVAEQV--EENGAEMQTEQTVQREEQKEKEQPQ 206

  Fly    70 ERAGSGASPVRRSRGSRTTPRKRTESKGGDKKVDTIPEEEPE------------NGKDVEKDAVE 122
            |...||||                     ::.::.||||.||            |...||:|...
Mosquito   207 EVVDSGAS---------------------EEVMEPIPEETPEELHETDATTAEQNVAPVEQDTGS 250

  Fly   123 EEKTV---------------APPAANESESEDRAKTE-----------DQQAQDDESCAE----- 156
            |..||               :|||..:||.|.:|...           |::.:::|...|
Mosquito   251 ETATVSARVDDRAQKERSERSPPARQDSEPESKAPAAASVEKVSHTNGDEEEEEEEEVKEANRDT 315

  Fly   157 --PAVVKDDDVEKEDLKP--QQEVPTSTDDDTKQSEPEQEVKVPSPSSKDEEHLKTTSDVLDIQT 217
              ...|:.:|. ::|.||  .....|..:.|:.:|.||:|.:......:||: ::..:|....:.
Mosquito   316 ERQKTVEPEDA-RDDSKPVVNNRSRTRQESDSNESAPEEEQRAEDEEEEDEK-MEEKADPRPTKR 378

  Fly   218 EEVDERDEEASAPAERR--ETKKRHKEQIKEQQPAEEEEHKENHKQIDENPEQIHDEPADLSND- 279
            .|.:.:.||.|..|:..  ......:|:.|:.....::..:::|..::.|.:|.:|  ::.:.|
Mosquito   379 GEREVQPEEPSGGADESMDAATSGTEEEAKDASSRSKQSRRDSHDAVESNRKQRND--SETARDR 441

  Fly   280 ------KHD-PCLNSSA------------TNTTGAPVLQQQRS------------------VRKR 307
                  ||| |.....|            |:..|....|||:.                  .|||
Mosquito   442 RSPAKAKHDSPPSKEDANEEELEAGEIKDTDQQGTAEQQQQQQQCSKEEGAALEAPKIRPLQRKR 506

  Fly   308 KWLTNKKSSDRTPPVLAISTDSLKNIIADVVQPVPLSDVQLESSSEEEGL--------------- 357
            :||:: ||:|..|.|:.||||||||||:| |:||||:||:|:||||.||.
Mosquito   507 RWLSS-KSADAKPAVITISTDSLKNIISD-VKPVPLADVKLDSSSEPEGADDAPSADENEKDRVK 569

  Fly   358 ---------VTSDRDSERSASPAPPSEASKDRDNKGNTANTCDTTAEASADN-EGAGAAPPAAAD 412
                     ||..:..::....||..:..:....|.|.|.  |..|:...:| :|||.......:
Mosquito   570 RKVREVNEPVTQHQPQQQPQQLAPLPQRRRPSAEKENIAT--DEAADGETNNGDGAGMKQKPVGE 632

  Fly   413 TVS-----AQVSLSKATVSTAAPHIVRDPSPARNRASHVLYITNLVRPFTVLQLKGLLARTGKIV 472
            .::     :.||...:||||.|| :||.||||::..|::||||||||||||||||||||||||||
Mosquito   633 KIALTRKISIVSDDGSTVSTKAP-VVRPPSPAKHLTSNILYITNLVRPFTVLQLKGLLARTGKIV 696

  Fly   473 EEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVDFGSRTDMDRAILST-KDE 536
             |:|||||:|||||||.|.|||||.||||||||:||||||||||.|||||...||:||||| :|.
Mosquito   697 -ENGFWIDKIKSKCYVKYETEDEATETRHALHGIRWPVSNPKCLVVDFGSEEAMDKAILSTLEDG 760

  Fly   537 APRYGQENTRDNQQSGNAWSRLEPSDKKPARPVREWDVGKKEPSDHDKHSNDRR--RDSKDRLDS 599
            |.|...|..:|.::.|  |||.....::..|.|||||:|||:..|.::   |.|  ||:....|.
Mosquito   761 ALRATVEGAKDGKEFG--WSRDAVKKEETVRRVREWDLGKKDAFDPER---DVRGGRDAAGLADK 820

  Fly   600 RSRDAERAGQERKRSRD---REGRGR-------DRERERLDRNA-------HARSRSGSPASK-T 646
            ....|:|||:||.|..:   |:|||.       ||..:|..|:|       ..||.|.|||.| .
Mosquito   821 DKLGADRAGRERGREMEEEHRDGRGTRLDGPPGDRSLDRGKRSAEREFGRERRRSTSVSPARKFK 885

  Fly   647 KKENEPPIRLLDDLFRKTKGTPCIYWLPLTPEAIAEKEAFRQKRIEEHKLRI------------- 698
            |||||||||||||||||||.||||||||||.|.||.||..|:|.:.||..|:
Mosquito   886 KKENEPPIRLLDDLFRKTKTTPCIYWLPLTTEQIAIKEEQRRKNMAEHLRRVEEQRKQEEERDRE 950

  Fly   699 --KERE----ERQKEREKDRDRQRETRRNRSNERRRSRSRERER 736
              :|||    ||::|||:||:|:|:..|:|..:|||||||||.|
Mosquito   951 RKRERERRDRERERERERDRERERDRERDRDRDRRRSRSRERSR 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acn	NP_609935.1	PTZ00121	<50..>251	CDD:173412	51/249 (20%)
		RRM_ACINU	444..530	CDD:409866	71/85 (84%)
		RSB_motif	599..693	CDD:465085	59/111 (53%)
Acn	XP_061518950.1	None