DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ttc19 and KLCR2

DIOPT Version :9

Sequence 1:	NP_609934.3	Gene:	Ttc19 / 35172	FlyBaseID:	FBgn0032744	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001326010.1	Gene:	KLCR2 / 822420	AraportID:	AT3G27960	Length:	663	Species:	Arabidopsis thaliana

Alignment Length:	172	Identity:	37/172 - (21%)
Similarity:	77/172 - (44%)	Gaps:	16/172 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 ITYVFDLMANLAMEREQFKKAEKIFTDVMKRLFAEGHTEESPKILHISSKIAHMSQLQGDLEKSF 200
            |:.::..|..|....:..::|.||:.:      |.|   :...|..|.:::..::.:.|:..:|:
plant   460 ISAIYQSMNELDQALKLLRRALKIYAN------APG---QQNTIAGIEAQMGVVTYMMGNYSESY 515

  Fly   201 QGFTWTLQQLAKLLEKMPDDKDILELYGLTKNWFGQLLMKQGKYLEAKNLFKEAFDTLINVYGAV 265
            ..|...:.:.....||.      ..|:|:..|..|...:::....||.:||:||...|....|..
plant   516 DIFKSAISKFRNSGEKK------TALFGIALNQMGLACVQRYAINEAADLFEEAKTILEKECGPY 574

  Fly   266 NDASVTILNNISVAYVNLEKYAEARETLLEAMELTKELKDAT 307
            :..::.:.:|::..|..:.:..:|.| :||.:..|:|.|..|
plant   575 HPDTLAVYSNLAGTYDAMGRLDDAIE-ILEYVVGTREEKLGT 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ttc19	NP_609934.3	TPR_12	235..302	CDD:290160	16/66 (24%)
		TPR repeat	269..299	CDD:276809	6/29 (21%)
		TPR_11	272..339	CDD:290150	10/36 (28%)
		TPR repeat	304..338	CDD:276809	2/4 (50%)
KLCR2	NP_001326010.1	TPR_12	153..229	CDD:315987
		TPR repeat	203..228	CDD:276809
		TPR	239..486	CDD:223533	6/25 (24%)
		TPR repeat	246..271	CDD:276809
		TPR repeat	286..313	CDD:276809
		TPR repeat	318..364	CDD:276809
		TPR_12	367..443	CDD:315987
		TPR repeat	373..405	CDD:276809
		TPR_12	409..484	CDD:315987	5/23 (22%)
		TPR repeat	410..440	CDD:276809
		TPR repeat	454..482	CDD:276809	4/21 (19%)
		TPR repeat	488..523	CDD:276809	6/37 (16%)
		TPR_12	494..569	CDD:315987	18/80 (23%)
		TPR repeat	528..566	CDD:276809	12/43 (28%)
		TPR_12	538..603	CDD:315987	14/65 (22%)
		TPR repeat	579..603	CDD:276809	4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1840
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810