DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ttc19 and klc4

DIOPT Version :9

Sequence 1:	NP_609934.3	Gene:	Ttc19 / 35172	FlyBaseID:	FBgn0032744	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001017813.1	Gene:	klc4 / 550511	ZFINID:	ZDB-GENE-050417-350	Length:	185	Species:	Danio rerio

Alignment Length:	217	Identity:	31/217 - (14%)
Similarity:	77/217 - (35%)	Gaps:	77/217 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 EKEETPEEKLIKTIKRSILCIQREQ-----------YDKAEQMLHLALRMAQDIQSKDGITYVFD 141
            |..::....:::::..:|.|:::::           ..|:.:|:.|.|..||          |..
Zfish    32 EALKSEHNSILQSLLETIQCLKKDEEASLVHEKSSLLRKSVEMIELGLGEAQ----------VMM 86

  Fly   142 LMANLAMEREQFKKAEKIFTDVMKRLFAEGHTEESPKILHISSKIAHMSQLQGDLEKSFQGFTWT 206
            .::|                                   |:::..:...:|:..:.:..|...|.
Zfish    87 ALSN-----------------------------------HLNAVESEKQKLRAQVRRLCQENQWL 116

  Fly   207 LQQLAKLLEKM-PDDKDILELYGLTKNWFGQLLMKQGKYLEAKNLFKEAFDTLINVYGAVNDASV 270
            ..:||....|: ..::.:.:            |.::.|:||..|..|:..|      ||..:.|.
Zfish   117 RDELANTQHKVQKSEQSVAQ------------LEEEKKHLEFMNQLKKYDD------GATPEVSP 163

  Fly   271 --TILNNISVAYVNLEKYAEAR 290
              .:..::|::...|::..|::
Zfish   164 HNDMHRDVSLSVRQLKRLRESK 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ttc19	NP_609934.3	TPR_12	235..302	CDD:290160	13/58 (22%)
		TPR repeat	269..299	CDD:276809	4/24 (17%)
		TPR_11	272..339	CDD:290150	3/19 (16%)
		TPR repeat	304..338	CDD:276809
klc4	NP_001017813.1	SMC_prok_B	31..>145	CDD:274008	20/169 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910