DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ttc19 and Ttc28

DIOPT Version :9

Sequence 1:NP_609934.3 Gene:Ttc19 / 35172 FlyBaseID:FBgn0032744 Length:369 Species:Drosophila melanogaster
Sequence 2:XP_006249646.1 Gene:Ttc28 / 304558 RGDID:1594541 Length:2451 Species:Rattus norvegicus


Alignment Length:268 Identity:65/268 - (24%)
Similarity:104/268 - (38%) Gaps:48/268 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   110 REQYDKAEQMLHLALRMAQDIQSKD-------GITYVFDLMANLAMEREQFKKAEKIFTDVMKRL 167
            |..:|||....:..|.:||::..|.       |:.:....|.:|...|:..::...|..|:..|.
  Rat   401 RRNFDKAMSYHNCVLELAQELTEKPIEMRAYAGLGHAARCMQDLERARQYHEQQLSIAEDLKDRA 465

  Fly   168 FAEGHTEESPKILHISSKIAHMSQLQGDLEKSFQGFTWTLQQLAK----LLEKMPDDKDILELYG 228
             |||....:..|:|         |::||.:        |..:|.|    :.:::.|.......||
  Rat   466 -AEGRASSNLGIIH---------QMKGDYD--------TALKLHKTHLCIAQELSDYAAQGRAYG 512

  Fly   229 LTKNWFGQLLMKQGKYLEAKNLFKEAFDTLINVYGAVNDASVTILNNISVAYVNLEKYAEARETL 293
            ...|.:..|    |.|.:|....::.....:.|....:.||..  .|::|||..|..:..|.:..
  Rat   513 NMGNAYNAL----GMYDQAVKYHRQELQISMEVNDRASQASTH--GNLAVAYQALGAHDRALQHY 571

  Fly   294 LEAMELTKELKDATQEGILQANLGLVYLREGLMSQA----ENACRLAWKL------GKQHQNPDA 348
            ...:.:.:||:|...|....:|||..:...|...||    |...|||..|      ||...|   
  Rat   572 QNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHN--- 633

  Fly   349 VEQAEYCL 356
            :..|.|||
  Rat   634 LGYAHYCL 641

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ttc19NP_609934.3 TPR_12 235..302 CDD:290160 13/66 (20%)
TPR repeat 269..299 CDD:276809 7/29 (24%)
TPR_11 272..339 CDD:290150 20/70 (29%)
TPR repeat 304..338 CDD:276809 12/37 (32%)
Ttc28XP_006249646.1 TPR_11 57..117 CDD:290150
TPR repeat 85..115 CDD:276809
TPR_11 88..151 CDD:290150
TPR repeat 120..148 CDD:276809
TPR repeat 154..182 CDD:276809
TPR repeat 230..256 CDD:276809
TPR repeat 268..300 CDD:276809
TPR_11 269..339 CDD:290150
TPR repeat 305..337 CDD:276809
TPR_12 309..380 CDD:290160
TPR repeat 348..376 CDD:276809
TPR_7 351..385 CDD:289919
TPR 373..687 CDD:223533 65/268 (24%)
TPR repeat 387..417 CDD:276809 5/15 (33%)
TPR 388..420 CDD:197478 6/18 (33%)
TPR repeat 428..456 CDD:276809 4/27 (15%)
TPR repeat 469..496 CDD:276809 8/43 (19%)
TPR repeat 509..536 CDD:276809 7/30 (23%)
TPR_7 510..545 CDD:289919 8/38 (21%)
TPR repeat 548..576 CDD:276809 8/29 (28%)
TPR repeat 588..616 CDD:276809 7/27 (26%)
TPR_7 590..625 CDD:289919 11/34 (32%)
TPR repeat 627..657 CDD:276809 7/18 (39%)
TPR_7 630..664 CDD:289919 5/15 (33%)
TPR 688..989 CDD:223533
TPR repeat 706..733 CDD:276809
TPR repeat 748..776 CDD:276809
TPR 788..817 CDD:197478
TPR repeat 788..816 CDD:276809
TPR repeat 827..857 CDD:276809
TPR repeat 872..899 CDD:276809
TPR_7 873..905 CDD:289919
TPR repeat 910..944 CDD:276809
TPR repeat 951..976 CDD:276809
TPR_7 953..988 CDD:289919
TPR repeat 991..1019 CDD:276809
TPR_12 993..1061 CDD:290160
TPR repeat 1031..1059 CDD:276809
TPR_12 1032..1103 CDD:290160
TPR repeat 1069..1099 CDD:276809
TPR_11 1072..1140 CDD:290150
TPR repeat 1111..1137 CDD:276809
TPR repeat 1163..1188 CDD:276809
CHAT 1384..1707 CDD:289536
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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