Protein Alignment Ttc19 and Appbp2

DIOPT Version :9

• Sequence 1: NP_609934.3
• Gene: Ttc19 / 35172
• FlyBaseID: FBgn0032744
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_038941971.1
• Gene: Appbp2 / 303396
• RGDID: 1306488
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 57/299 - (19%)
• Similarity: 126/299 - (42%)
• Gaps: 73/299 - (24%)

  Fly    89 KEET---PEEKLIKTIKR-SILCIQREQYDKAEQMLHLALRMAQD-IQSKDG------ITYVFDL 142
            ||.|   |.:.::..::: |..|:.:.::.||||::..|:.:|:| ..||..      :.|.|.|
  Rat   305 KEITSGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYL 369

  Fly   143 M--ANLAMEREQFKKAEKIFTDVMKRLFAEGHTEESPKILHISS---KIAHMSQLQGDLEKSFQG 202
            :  .|:......::.|    .|:.:.:|       ..|.:|:::   .:|:.|.:.......|..
  Rat   370 LNVDNICQSVAIYQAA----LDIRQSVF-------GGKNIHVATAHEDLAYSSYVHQYSSGKFDN 423

  Fly   203 FTWTLQQLAKLLEK-MPDDKDILELYGLTKNWFGQLLMKQGKYLEA----------------KNL 250
            ..:..::...::.. :|:|               .||:...|.::|                :.|
  Rat   424 ALFHAERAIGIITHILPED---------------HLLLASSKRVKALILEEIAIDCHNKETEQRL 473

  Fly   251 FKEAFDTLIN-------VYGAVNDASVTILNNISVAYVNLEKYAEARETLLEAMELTKEL--KDA 306
            .:||.|..::       .:|..|..:.....|:...|.::.|:.||.|..::|:::.::|  ::.
  Rat   474 LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQED 538

  Fly   307 TQEGILQANLGLVYLREGLMSQAENACRLAWK---LGKQ 342
            .:..:...:|..:|..:  |:|.|||.:|..:   :||:
  Rat   539 YEVALSVGHLASLYNYD--MNQYENAEKLYLRSIAIGKK 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ttc19	NP_609934.3	TPR_12	235..302	CDD:290160	17/89 (19%)
		TPR repeat	269..299	CDD:276809	7/29 (24%)
		TPR_11	272..339	CDD:290150	16/71 (23%)
		TPR repeat	304..338	CDD:276809	8/33 (24%)
Appbp2	XP_038941971.1	TPR	274..581	CDD:223533	57/299 (19%)
		TPR_12	454..532	CDD:315987	14/77 (18%)
		TPR_12	498..575	CDD:315987	17/78 (22%)
		TPR repeat	500..528	CDD:276809	7/27 (26%)
		TPR repeat	541..572	CDD:276809	8/32 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1840
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900