Protein Alignment Ttc19 and ddl-3

DIOPT Version :9

• Sequence 1: NP_609934.3
• Gene: Ttc19 / 35172
• FlyBaseID: FBgn0032744
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001022475.1
• Gene: ddl-3 / 175087
• WormBaseID: WBGene00013217
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 83/373 - (22%)
• Similarity: 158/373 - (42%)
• Gaps: 63/373 - (16%)

  Fly    27 HLAPLKRSRYHQRSEFGCRPLCSNAAGYEVSWAAPPASGSSGG-----MFWAFSAAFTLNLFGGA 86
            |.:...|.::|:....|.:   :|..|   .|:....|.::||     :.|..:....|.:
 Worm    29 HSSGRSRQQHHRHGGSGGK---TNGGG---RWSRYGKSAATGGTTVLALSWMTTIKDVLGI---- 83

  Fly    87 DEKEETPEEKLIKTIKRSILCIQREQYDKAEQMLHLALRMAQDIQSKDGITYVFDLMANLAMERE 151
             ||.:...:.|.:.:|:|.|..:|.|||.|.|:|.|||..|::.:....||.|:|.|||...|:.
 Worm    84 -EKVQLDADPLKEKVKQSWLYRKRRQYDDAIQVLQLALEEAEERKEDMPITRVYDEMANTFYEKM 147

  Fly   152 QFKKAEKIFTDVMKRLF-AEGHTEESPKILHISSKIAHMSQLQGDLEKSFQGFTWTLQQLAKLLE 215
            ...:|:|.|..|::||. ..|..:..|:.:.:|.|:|.:...:||||.:..||...:::..|::|
 Worm   148 NLDEADKYFRIVIQRLVQLHGKKDFDPEFIGVSLKLADILAHRGDLESAESGFKHCVRRQMKVME 212

  Fly   216 K-----------MPDDK-----------DILELYGLTKNWFGQLLMK---QGKYLEAKNLFKEAF 255
            :           :.:|:           |.:.|:|:|...:...|:.   :.:..|.:....|..
 Worm   213 EHMKKFSVAHGALVEDRHTVDTFGPMYTDPIALFGMTLEAYANFLINYCGETRMAEVEEYIDEVM 277

  Fly   256 DTLINVYGAVNDASVTILNNISVAYVNLEKYAEARETLLEAMELTKELKDATQEGILQANLGLVY 320
            .....:|||.:..::.:|||.....|...::..|::.|...::                  .::|
 Worm   278 KISYQIYGASSAHTINMLNNFGATLVLKNRFELAKKYLAIGVD------------------RILY 324

  Fly   321 LREGLMSQAENACRLAWKLGKQHQNPDAVEQAEYCLNEIKTTLNGEKR 368
            :.|.........|..|..|....|..:|:   |:....::.:.:|:.|
 Worm   325 VNECAHMLPGYYCNYAESLFHTGQKNEAL---EFARKAVQMSRSGDDR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ttc19	NP_609934.3	TPR_12	235..302	CDD:290160	12/69 (17%)
		TPR repeat	269..299	CDD:276809	6/29 (21%)
		TPR_11	272..339	CDD:290150	10/66 (15%)
		TPR repeat	304..338	CDD:276809	4/33 (12%)
ddl-3	NP_001022475.1	TPR_12	102..157	CDD:290160	22/54 (41%)
		TPR repeat	126..162	CDD:276809	12/35 (34%)
		TPR_12	132..209	CDD:290160	25/76 (33%)
		TPR repeat	177..205	CDD:276809	9/27 (33%)
		TPR_12	249..315	CDD:290160	12/65 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167324
Domainoid	1	1.000	73	1.000	Domainoid score	I6025
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I3761
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D369100at33208
OrthoFinder	1	1.000	-	-		FOG0007221
OrthoInspector	1	1.000	-	-		oto19973
orthoMCL	1	0.900	-	-		OOG6_107899
Panther	1	1.100	-	-	LDO	PTHR13143
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4032
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.930