Protein Alignment hook and hook2

DIOPT Version :9

• Sequence 1: NP_476573.1
• Gene: hook / 35169
• FlyBaseID: FBgn0001202
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_957405.1
• Gene: hook2 / 394086
• ZFINID: ZDB-GENE-040426-1636
• Length: 476
• Species: Danio rerio
• Alignment Length: 725
• Identity: 142/725 - (19%)
• Similarity: 255/725 - (35%)
• Gaps: 295/725 - (40%)

  Fly     1 MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSN 65
            ||..|:::..||..|.::..:.: .|....|..|||:|..||:.....|.:.|||:||... |:|
Zfish     1 MSLNKHQLSDSLFIWLQSFQVPS-CASKHELTSGVAIAHVLNKIDSTWFNETWLSRIKEDG-GTN 63

  Fly    66 WRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQ 130
            |||::|||||:.||:.:||.|||:..:||...||
Zfish    64 WRLKVSNLKKILQSMMEYYHDVLSQQVSDEHVPD------------------------------- 97

  Fly   131 SYITEIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKAVQEDRDALAQK 195
                                                                             
Zfish    98 ----------------------------------------------------------------- 97

  Fly   196 CFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRRQLDL 260
                                                                             
Zfish    98 ----------------------------------------------------------------- 97

  Fly   261 LKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEA 325
                                                                             
Zfish    98 ----------------------------------------------------------------- 97

  Fly   326 QLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLD 390
                              |::||||:..|:|:..:.||:.:|....:.|::.:|::..::.||..
Zfish    98 ------------------VRLLEERNHVYMQRTCELEEEQRRATAIRSQLDSYKRQAHEMSAKHS 144

  Fly   391 AESSKNVKLEFDNKNLESKNLALQRAKDSLLKERDNLREAVDELKCGQLSSNTALTGT------- 448
            ||:.|..|.:|:.|||..|...|.:.::.|:.|||.|||..:||:|.|:... .||.:
Zfish   145 AEAMKAEKWQFEYKNLNDKYETLLKEREKLISERDTLRETTEELRCAQVQQQ-CLTDSMIGDAGA 208

  Fly   449 --TVSRELQPSATVEKLQRLEAENKAL-REGQGGQTALAQL---LDDANKRCENLREQLKTANER 507
              :::.|:.|:...:.:.||:.|||.| .:.:..:..|.:|   |::|.:|...|..|.:.:.::
Zfish   209 VGSLASEIMPTEFRDTVVRLQQENKMLCVQEESYRHRLEELQTQLEEAQRRQNTLETQNRLSQQQ 273

  Fly   508 ILSLS------------HASQSDDPI--LKESEFGKQIKQLMELNEQKTLQLEEAVTQ------S 552
            |..||            ..|:::|.|  |.:.:..:.:::|.|.:..  ||.:..|..      .
Zfish   274 ISDLSAQVEELQRALQEQDSRNEDVISSLLKKKLEEHLEKLHEAHSD--LQKKREVIDDLEPPLD 336

  Fly   553 TSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPR--------IASALDASVLEK 609
            .::..||.:|:..|..:::::...:.:|::.||||:.|||:::|:        ...||...:.||
Zfish   337 INMAKKVDELQEILKKKDEDMRRMEDRYKRYVEKARTVIKTLEPKQKLNPVPVEVQALKNQLSEK 401

  Fly   610 SADL--VEEEPKPKMS--VMEEQLMTSAFYRLGVNAQRDAIDSKLAILMGSGQTFLARQRQSA-P 669
            ...:  :|.:.:...|  ..||:|:.||:|.:|:...:.....:.:....|.|:|||:||||. .
Zfish   402 DRKIQHLEHDFEKTRSRHDQEEKLIISAWYNMGMALHQRVAGERSSSSSSSAQSFLAQQRQSTQA 466

  Fly   670 RKSLSAMKSK 679
            |:..|.::.:
Zfish   467 RRGFSRLQPR 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hook	NP_476573.1	HOOK	8..675	CDD:283312	138/712 (19%)
hook2	NP_957405.1	Lebercilin	244..398	CDD:292252	34/155 (22%)
		Prefoldin	248..353	CDD:298833	22/106 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CMK1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373785at33208
OrthoFinder	1	1.000	-	-		FOG0001903
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101918
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4604
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.680