Protein Alignment hook and Hook1

DIOPT Version :9

• Sequence 1: NP_476573.1
• Gene: hook / 35169
• FlyBaseID: FBgn0001202
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_038965825.1
• Gene: Hook1 / 313370
• RGDID: 1309987
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 721
• Identity: 231/721 - (32%)
• Similarity: 380/721 - (52%)
• Gaps: 80/721 - (11%)

  Fly    12 LLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLRMSNLKKV 76
            ||:.|||.   :|..|.:.|.:||.:||.|:|.....|:::|||:|| ..||.|||::.||||||
  Rat    26 LLQTFKTA---SPCQDVKQLTNGVTMAQVLHQIDVAWFSESWLSRIK-DDVGDNWRIKASNLKKV 86

  Fly    77 TQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQSYITEIMCLEE 141
            ...:..||.:.|...:|:...|||.:|.|..|..||.|||||:|||||||.:||.:|..||.|||
  Rat    87 LHGITSYYHEFLGQQISEELIPDLNQITESSDPVELGRLLQLILGCAVNCEKKQEHIKNIMTLEE 151

  Fly   142 ELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKAVQEDRDALAQKCFETEKKMLLL 206
            .:|..:|.|:|||.:....|:|.......|.:..:..|.:.:....:::.|.|:|.|.:.::..|
  Rat   152 SVQHVVMTAIQELMSKEIVSSPASDAVGELEQQLKRALEELQEALAEKEELKQRCQELDMQVTAL 216

  Fly   207 IDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGA 271
            .|||.:|..|...:.::..:|         ||....|....:.:|..::.||:.|:||..:.|.|
  Rat   217 QDEKNSLVSENEMMNEKLDQL---------DGSFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAA 272

  Fly   272 REDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLED 336
            ::|.::..::.:..|:..|.|.:||...:.|...||||:||||.::||....|:.::.|::||:|
  Rat   273 KDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQD 337

  Fly   337 YNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEF 401
            .|||:||||.|:|.:..|:......||:.|:....:.|:|.:|:::||||.||.:||.:...|.|
  Rat   338 LNDLRKQVKSLQETNMMYMHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAF 402

  Fly   402 DNKNLESKNLALQRAKDSLLKERDNLREAVDELKC--------GQLSSNTALTGTTVSRELQPSA 458
            :.|.||.|:..|.:.|:.|:::||.|:|..:||:|        .|..|:...:...::.|:.|..
  Rat   403 EMKRLEEKHETLLKEKERLIEQRDTLKETNEELRCSKAQQDHLNQADSSATKSYENLAAEIMPVE 467

  Fly   459 TVEKLQRLEAENKALREGQGGQTALAQLLDDANKRCENLREQL--------------KTANERIL 509
            ..|...||:.|||.||..|.|         ..|:|.|.|:|||              :.:.|||.
  Rat   468 YREVFIRLQHENKMLRLQQEG---------TENERIEQLQEQLEQKHRKMNELETEQRLSKERIG 523

  Fly   510 SLS------HASQSDDPILKESEFGKQIKQLMELNEQKTLQLEEAVTQSTSL-----------QC 557
            .|.      ..|..:.....|.|...::||.:|.:.:|..::.|.:.:...|           ..
  Rat   524 ELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQNAQ 588

  Fly   558 KVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRI--ASA----LDASVLEKS--ADLV 614
            |:::||..|..:::::...:.:|:..:|||:.|||::||::  |||    |...:.||.  .:::
  Rat   589 KISELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKDRRIEIL 653

  Fly   615 EEEPK-PKMSVMEEQLMTSAFYRLGVNAQRDAIDSKL---------AILMGSGQTFLARQRQ-SA 668
            |.|.| .|....||:|:.||:|...:..|:..::|:|         ::.....::|||:||. ::
  Rat   654 ESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITS 718

  Fly   669 PRKSLS 674
            .|::||
  Rat   719 TRRNLS 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hook	NP_476573.1	HOOK	8..675	CDD:283312	231/721 (32%)
Hook1	XP_038965825.1	HkD_Hook1	27..168	CDD:411796	68/144 (47%)
		HOOK	191..724	CDD:398962	156/550 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	352	1.000	Domainoid score	I976
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2182
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373785at33208
OrthoFinder	1	1.000	-	-		FOG0001903
OrthoInspector	1	1.000	-	-		otm45988
orthoMCL	1	0.900	-	-		OOG6_101918
Panther	1	1.100	-	-	LDO	PTHR18947
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2196
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.930