Protein Alignment hook and hook2

DIOPT Version :9

• Sequence 1: NP_476573.1
• Gene: hook / 35169
• FlyBaseID: FBgn0001202
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_002938530.1
• Gene: hook2 / 100497596
• XenbaseID: XB-GENE-991660
• Length: 721
• Species: Xenopus tropicalis
• Alignment Length: 722
• Identity: 229/722 - (31%)
• Similarity: 395/722 - (54%)
• Gaps: 75/722 - (10%)

  Fly     5 KNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLR 69
            |.|:..|||.|.:|..::.|.:..|.|..|||:||.||:..|..|.:|||.::|.... .|||::
 Frog     6 KGELCDSLLTWMQTFQVSGPCSSYEDLTGGVAIAQVLNRIDPSWFNEAWLVRVKQDTT-ENWRIK 69

  Fly    70 MSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQSYIT 134
            :||||::.||:.:||.|||.:.:||...||:..|.|..:..||.:::|||||||::|.:|:.:|.
 Frog    70 VSNLKRILQSILEYYQDVLGHPVSDDHIPDVALIGEFSNAAELRKMVQLVLGCAISCDKKEEHIQ 134

  Fly   135 EIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKA-----VQEDRD---A 191
            :||.|.|.:|..:|.::|||    .:..|...|.|.....     .||::     :.||.|   .
 Frog   135 QIMTLGESVQQAVMESIQEL----LSKDPTDAVTSESYIN-----YDSQSRKYYFLSEDNDEKNE 190

  Fly   192 LAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRR 256
            :.|:|.:.|:::.||::||.||..|...|:::    ::.|        .:|..|..:.:...|:.
 Frog   191 ILQRCHDLEQQVSLLMEEKKNLVGENRNLREQ----QEQS--------GMGTPQLFNKKLLLLQS 243

  Fly   257 QLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLK 321
            |::.|:||..:.|.:|:|.:.:.|:.|.|:..:|.|.::|...:.|...|:||:||||.|:|::.
 Frog   244 QIEQLQEENYRLESSRDDYRQRCQELDRDIQELQQRNQDLTGLAHEAQALRDEMDVLRHSSDRVG 308

  Fly   322 ICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLH 386
            ..|:.:::|||||||..||::|||:||||:..|:|:..|.||:..:...::||:|...::||:||
 Frog   309 KLESLVESYKKKLEDLGDLRRQVKLLEERNTVYMQRTCQLEEELHKANASRGQLENLSRQIQELH 373

  Fly   387 AKLDAESSKNVKLEFDNKNLESKNLALQRAKDSLLKERDNLREAVDELKCGQL------SSNTAL 445
            .|...||.:..|.:|:.:.|:.|..|||:.::.|:.|||:|||..|||:|..|      .::..|
 Frog   374 KKHSTESLRAEKWQFEFQTLKEKFEALQKERERLITERDSLRETNDELRCSHLQQTCLGQADVLL 438

  Fly   446 TGTT-----VSRELQPSATVEKLQRLEAENKAL--REG--QGGQTALAQLLDDANKRCENLREQL 501
            :|::     ::.|:.|:...|.:.||:.|||.|  :|.  |.....|..||:::|:....:..:.
 Frog   439 SGSSPPLENLAAEIVPAELRETVMRLQQENKMLCTQEASYQDRLCDLQNLLEESNRSKNRMESES 503

  Fly   502 KTANERILSLSHASQSDDPILKE----SEFGKQIKQLME-----LNE-----QKTLQLEEAVTQS 552
            :...::|..|....:.....|:|    :|...|:|:.:|     |::     ||..:..|.:...
 Frog   504 RLQQQQIKELKAQVEELQKHLREQGNRAEDSSQLKRKLEEHLEMLHDAHSELQKKREYIETLEPK 568

  Fly   553 TSLQC--KVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIASALDASVLEKSADLVE 615
            ..|..  ||.:|:..|..:|:::...:.:|::.|:||:.||||:||:..:.:...:......|.|
 Frog   569 ADLNMSRKVNELQQILRQKEEDMRAMEDRYKRYVDKARTVIKSLDPKQQNCIPPEIQALKNQLQE 633

  Fly   616 EEPK--------PKMSVM---EEQLMTSAFYRLGVNAQRDAIDSKLAILMGSGQTFLARQR--QS 667
            ::.:        .|..|.   ||:|:.||:|.:|:...:.|.|.:.....|: |:|||:||  .:
 Frog   634 KDTRIRHLETDYEKTKVQRDHEEKLIISAWYNMGMALHQKATDERSQPPNGA-QSFLAQQRLATN 697

  Fly   668 APRKSLS 674
            |.|..:|
 Frog   698 ARRGQIS 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hook	NP_476573.1	HOOK	8..675	CDD:283312	227/719 (32%)
hook2	XP_002938530.1	HOOK	9..702	CDD:368526	226/715 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	328	1.000	Domainoid score	I1175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2079
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373785at33208
OrthoFinder	1	1.000	-	-		FOG0001903
OrthoInspector	1	1.000	-	-		otm49074
Panther	1	1.100	-	-	O	PTHR18947
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2196
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070