Protein Alignment hook and hook1

DIOPT Version :9

• Sequence 1: NP_476573.1
• Gene: hook / 35169
• FlyBaseID: FBgn0001202
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_012815933.1
• Gene: hook1 / 100125063
• XenbaseID: XB-GENE-975863
• Length: 717
• Species: Xenopus tropicalis
• Alignment Length: 717
• Identity: 233/717 - (32%)
• Similarity: 383/717 - (53%)
• Gaps: 71/717 - (9%)

  Fly     1 MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSN 65
            |:..:||:..||:.|.:|.|..||....:.|.:|||:||.|::.....|..:|||:|| ..||.|
 Frog     1 MAEKENELCESLIIWLQTFNTAAPCQTIQDLTNGVAMAQILHEIDYTWFDVSWLSRIK-DDVGDN 64

  Fly    66 WRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQ 130
            .|:::.||||:.|.:.|||.:.|:..:.:|..|:|..||:..|..|:.|||||:|||||||.:||
 Frog    65 KRIKIHNLKKILQGIVDYYREFLDQHILEFLLPNLNLIADHSDATEMGRLLQLILGCAVNCEKKQ 129

  Fly   131 SYITEIMCLEEELQANIMRALQELEATRQASTP----EGGVASSLSRGSRTGLLDSKAVQEDRDA 191
            .:|..||.|||.:|..:|.|:|||.:.....:|    .|.:.|.|.| :...|.:::|.||:
 Frog   130 EHIQVIMTLEESVQHVVMTAIQELMSKDTLDSPTSDLPGDLESQLRR-TIDALHEAQAEQEE--- 190

  Fly   192 LAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRR 256
            |.|:|.|.:.::..|.||:..|..|. :||.|  ||.|..|.  |:     |....|.:|::::.
 Frog   191 LKQRCEELDLQVAALQDERNCLIAET-ELQNE--RLNQLDTF--DE-----PSIMVSKKYSQMQM 245

  Fly   257 QLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLK 321
            ||:.:||:..:.|.|:||.:|..::.:..|:..|.|..||...:.|...||||:|:||.:.||..
 Frog   246 QLEQMKEDNYRLEAAKEDYRIHCEELEKQLVETQNRNVELASLAEESRALKDEIDILRATADKAS 310

  Fly   322 ICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLH 386
            ..|:.::||::||||..||::|||.||:.:..|:......|||.|:....:.|:|.:|:::|:||
 Frog   311 KLESTVETYRRKLEDLADLRRQVKSLEDTNLVYMHNTVSLEEDLKKANAARVQLESYKRQVQELH 375

  Fly   387 AKLDAESSKNVKLEFDNKNLESKNLALQRAKDSLLKERDNLREAVDELKCGQLS------SNTAL 445
            .||..||.:...|.::.|.|:.|..||.:.|:.||.:...|:|..:||:|..:.      |:...
 Frog   376 NKLSLESKRADTLAYEMKRLQEKEDALLKEKERLLVQCTTLKETNEELRCSMIQQDHLNLSDGVK 440

  Fly   446 TGTTVSRELQPSATVEKLQRLEAENKALR---EGQGGQ--TALAQLLDDANKRCENLREQLKTAN 505
            ....::.||.|:...|...||..|||.||   ||...|  |.|...|::..::...|..:.:...
 Frog   441 NVDNLAAELLPAEYREMFIRLHHENKMLRLQQEGSENQKITDLQTQLEEKQRKMSELETENRLNT 505

  Fly   506 ERILSL---------------SHASQSDDPILKES-----EFGKQIKQLMELNEQKTLQLEEAVT 550
            ||:..|               :.|.......||::     |..|::.:.:|...:....|:..|.
 Frog   506 ERVEELQLQVGDLQKTLQNEGTEAETVGSSTLKKTIEAQMEKLKEVHEAIETKRELLEDLQPDVN 570

  Fly   551 QSTSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIASALDASVL-------- 607
            |:|.   ::.:||..|..:::::...:.:|:..:||||.|||::||::..| .|.::
 Frog   571 QNTQ---RIEELEAALQKKDEDMKAMEDRYKVYLEKAKNVIKTLDPKLNPA-SAEIMLLRKQLTE 631

  Fly   608 -EKSADLVEEE-PKPKMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAILMGSG-------QTFLAR 663
             :|..:|:|.| .:.|:...||:|:.:|:|...:..|:.|::|:|:...|.|       ::|||:
 Frog   632 KDKKIELLESECQQAKLREYEEKLIVTAWYNKSLAHQKLAMESRLSGRGGMGSEATTSSRSFLAQ 696

  Fly   664 QR 665
            ||
 Frog   697 QR 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hook	NP_476573.1	HOOK	8..675	CDD:283312	230/710 (32%)
hook1	XP_012815933.1	HOOK	8..709	CDD:368526	230/710 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	328	1.000	Domainoid score	I1175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2079
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373785at33208
OrthoFinder	1	1.000	-	-		FOG0001903
OrthoInspector	1	1.000	-	-		otm49074
Panther	1	1.100	-	-	LDO	PTHR18947
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070