Protein Alignment Sidpn and HES4

DIOPT Version :10

• Sequence 1: NP_523599.1
• Gene: Sidpn / 35168
• FlyBaseID: FBgn0032741
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001135939.1
• Gene: HES4 / 57801
• HGNCID: 24149
• Length: 247
• Species: Homo sapiens
• Alignment Length: 194
• Identity: 76/194 - (39%)
• Similarity: 104/194 - (53%)
• Gaps: 41/194 - (21%)

  Fly     8 DYSKNKSAPGIGFTAAGSTNGSGIKSIGLVSSTQNVTSSQDISKRTNKPLMEKRRRARINQSLAI 72
            ::.|..|.||:. .|.|...|.|         ||.|...|     ::||:||||||||||:|||.
Human    33 EHRKVGSRPGVR-GATGGREGRG---------TQPVPDPQ-----SSKPVMEKRRRARINESLAQ 82

  Fly    73 LKALILESTKTQNAKNGEGQAKHTKLEKADILELTVRHFQRHRNLD-------DPTV-NKYRAGY 129
            ||.|||::.:.::       ::|:|||||||||:||||.:..|.:.       ||.| .|||||:
Human    83 LKTLILDALRKES-------SRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGF 140

  Fly   130 TDCAREVARYLATPEPPPMGTMPTLAEPGSKARLLRHLDQCIAEIDVEICPH--STAAFAESPS 191
            .:|..||.|:||..|..|...         ::|||.||..|:.::.....|.  |.||.||:|:
Human   141 HECLAEVNRFLAGCEGVPADV---------RSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPA 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	bHLH_O_HES	58..116	CDD:381416	32/57 (56%)
		Hairy_orange	124..172	CDD:462193	19/47 (40%)
HES4	NP_001135939.1	bHLH-O_HES1_4	62..121	CDD:381465	36/70 (51%)
		Hairy_orange	135..174	CDD:462193	19/47 (40%)