Protein Alignment Sidpn and HES6

DIOPT Version :9

• Sequence 1: NP_523599.1
• Gene: Sidpn / 35168
• FlyBaseID: FBgn0032741
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_061115.2
• Gene: HES6 / 55502
• HGNCID: 18254
• Length: 224
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 65/237 - (27%)
• Similarity: 92/237 - (38%)
• Gaps: 53/237 - (22%)

  Fly    51 KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTVRHFQ--- 112
            ::..|||:||:||||||:||..|:.|:            .|.....|||.|::||||||..|
Human    26 RKARKPLVEKKRRARINESLQELRLLL------------AGAEVQAKLENAEVLELTVRRVQGVL 78

  Fly   113 ----RHR-NLDDPTVNKYRAGYTDCAREVARYLATPEPPPMGTMPTLAEPGSKARLLRHLDQCIA 172
                |.| .|......::.|||..|..||..:::|.:    ....|:|     |.||.||
Human    79 RGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQ----AIDATVA-----AELLNHL----- 129

  Fly   173 EIDVEICPHSTAAFAESPSSSSCF-DLNHGKKSQPEEHSLDYSSQDSNPVDYSKGLKMVAAEQRT 236
               :|..|     ..|..|..... |...|....|............:|:....|    ..:...
Human   130 ---LESMP-----LREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPG----PGDDLC 182

  Fly   237 LPVTPAPQDENNNRGLQAQAQTP--IPIQVQSQTQGQTSPHV 276
            ..:..||:.|.:    ||.|:.|  :|..:.|.|..|.:..|
Human   183 SDLEEAPEAELS----QAPAEGPDLVPAALGSLTTAQIARSV 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	HLH	48..117	CDD:238036	29/73 (40%)
		Hairy_orange	125..172	CDD:284859	14/46 (30%)
HES6	NP_061115.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		0/4 (0%)
		HLH	23..75	CDD:238036	26/60 (43%)
		Hairy_orange	96..134	CDD:311465	15/54 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..205		12/65 (18%)
		WRPW motif	221..224		65/237 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810