Protein Alignment Sidpn and hes4

DIOPT Version :10

• Sequence 1: NP_523599.1
• Gene: Sidpn / 35168
• FlyBaseID: FBgn0032741
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_988870.1
• Gene: hes4 / 394465
• XenbaseID: XB-GENE-487830
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 94/290 - (32%)
• Similarity: 128/290 - (44%)
• Gaps: 91/290 - (31%)

  Fly    38 SSTQNVTSSQDIS--KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEK 100
            ||.|.....:..|  ::::||:||||||||||:||..||.|||::.|       :..::|:||||
 Frog    20 SSAQTPDKPKSASEHRKSSKPIMEKRRRARINESLGQLKTLILDALK-------KDSSRHSKLEK 77

  Fly   101 ADILELTVRHFQRHRNLD----------DPTV-NKYRAGYTDCAREVARYLATPEPPPMGTMPTL 154
            |||||:||:|.   |||.          ||:| .|||||:.:|..||.|:|:|.|    |....:
 Frog    78 ADILEMTVKHL---RNLQRVQMTAALTADPSVLGKYRAGFNECMNEVTRFLSTCE----GVNTEV 135

  Fly   155 AEPGSKARLLRHLDQCIAEI---------------DVEICPHSTAAFAESPSSSSCFDLNHGKKS 204
                 :.|||.||..|:.:|               .|:: |.||.|    |....|       |.
 Frog   136 -----RTRLLGHLSSCLGQIVAMNYQQPPSSQQPLHVQL-PSSTPA----PVPMPC-------KV 183

  Fly   205 QPEEHSLDYSSQDSNPVDYSKGLKMVAAEQ------------RTLPVTPAPQDENNNRGLQAQAQ 257
            .|.|        ..:|..:..|.::|.|..            .|.|....|...|.|      ..
 Frog   184 NPAE--------AISPKVFQGGFQLVPATDGQFAFLIPNPAYTTSPGPVIPLYANTN------VT 234

  Fly   258 TPIPIQVQSQTQGQTS-----PHV-DAVAP 281
            :|...|.||..||.|:     ||: .||:|
 Frog   235 SPGGPQSQSPVQGLTTFGHKMPHMAQAVSP 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	bHLH_O_HES	58..116	CDD:381416	31/57 (54%)
		Hairy_orange	124..172	CDD:462193	19/47 (40%)
hes4	NP_988870.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		7/23 (30%)
		bHLH-O_HES1_4	33..95	CDD:381465	36/71 (51%)
		Hairy_orange	109..147	CDD:462193	18/46 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..281		2/3 (67%)
		WRPW motif. /evidence=ECO:0000255	278..281