DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sidpn and heyl

DIOPT Version :9

Sequence 1:	NP_523599.1	Gene:	Sidpn / 35168	FlyBaseID:	FBgn0032741	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_859425.1	Gene:	heyl / 335134	ZFINID:	ZDB-GENE-030131-7074	Length:	310	Species:	Danio rerio

Alignment Length:	339	Identity:	85/339 - (25%)
Similarity:	133/339 - (39%)	Gaps:	119/339 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KRDKDYSKNKS--------------APGIGFTAAGSTNGSGIKSIGLVSSTQNVTSSQDISKRTN 54
            ||..|||...|              .|..|..:.|||                   ||.::::..
Zfish     2 KRPHDYSSPDSDTDELIDVGQEDSYCPVTGSMSPGST-------------------SQILARKKR 47

  Fly    55 KPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTVRHFQ------- 112
            :.::|||||.|||.||:.|:.|:..:.:.|.:         :|||||:||::||.|.:
Zfish    48 RGIIEKRRRDRINHSLSELRRLVPSAFEKQGS---------SKLEKAEILQMTVDHLKLLHAMGG 103

  Fly   113 ------RHRNLDDPTVNKYRA-GYTDCAREVARYLATPE----PPPMGTMPTLAEPGSKARLLRH 166
                  |...:|      ||. |:.:|..||.|||::.|    ..|:|           |||:.|
Zfish   104 KGYFDARALAVD------YRTLGFRECVGEVVRYLSSLEGVESSDPIG-----------ARLVSH 151

  Fly   167 LDQCIAEID--------VEICPHSTAAF-----AESPSSSSCFDLNHGKKSQPEEHS--LDYSSQ 216
            |..|.:|:|        :...|...|:|     |..|:||:.|..|..:...|...:  |.|.
Zfish   152 LSHCASELDPLLQSPAALPFPPWPWASFPQLQAASPPASSTPFPPNARRDLTPHGTATILGYP-- 214

  Fly   217 DSNPVDYSKGLKMVAAEQRTLPVTPAPQDENNNRGLQAQAQTP-IPIQV----QSQTQGQTSPHV 276
                   |..|:|.:...:...:.||         |.:..|.| :|..:    |...:|:|.|..
Zfish   215 -------SPALRMGSLSTQGTILNPA---------LTSVRQLPSVPGHLHRLQQHSPEGRTVPSS 263

  Fly   277 DA----VAPSELSY 286
            .:    .:|.::|:
Zfish   264 SSSSSNSSPPQISF 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	HLH	48..117	CDD:238036	24/81 (30%)
Sidpn	NP_523599.1	Hairy_orange	125..172	CDD:284859	18/51 (35%)
heyl	NP_859425.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		6/18 (33%)
		HLH	44..101	CDD:238036	23/65 (35%)
		ORANGE	115..159	CDD:128787	19/60 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..208		7/25 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..310		6/30 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.770