Protein Alignment Sidpn and HEYL

DIOPT Version :9

• Sequence 1: NP_523599.1
• Gene: Sidpn / 35168
• FlyBaseID: FBgn0032741
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_055386.2
• Gene: HEYL / 26508
• HGNCID: 4882
• Length: 328
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 72/270 - (26%)
• Similarity: 117/270 - (43%)
• Gaps: 55/270 - (20%)

  Fly    44 TSSQDISKRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTV 108
            :|||..:::.::.::|||||.|||.||:.|:.|:..:.:.|.:         :|||||::|::||
Human    37 SSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS---------SKLEKAEVLQMTV 92

  Fly   109 RH-----------FQRHRNLDDPTVNKYRAGYTDCAREVARYLATPEPPPMGTMPTLAEPGSKAR 162
            .|           |...|.|   .|:....|:.:|..||.|||...|.|.....|.      :.|
Human    93 DHLKMLHATGGTGFFDARAL---AVDFRSIGFRECLTEVIRYLGVLEGPSSRADPV------RIR 148

  Fly   163 LLRHLDQCIAEIDVEICPHSTAAFAESPSS--SSCFDL----NH----GKKSQPEEHSLDYSSQD 217
            ||.||:...||::....|....||...|.|  .||..|    |.    |:...|   .|...|..
Human   149 LLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSP---VLPGVSSP 210

  Fly   218 SNPVDYSKGLKMVAAEQRTLPVTPAPQDENNNRGLQA--------QAQTPIPIQVQSQT--QGQT 272
            :.|:   ..|:.....:.|..:.||.::...:||..:        :..||:|:...|:.  ....
Human   211 AYPI---PALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHI 272

  Fly   273 SPHVDAVAPS 282
            :|.:.:.:|:
Human   273 APLLQSSSPT 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	HLH	48..117	CDD:238036	24/79 (30%)
		Hairy_orange	125..172	CDD:284859	15/46 (33%)
HEYL	NP_055386.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..57		7/19 (37%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	42..111		23/77 (30%)
		HLH	42..100	CDD:238036	22/66 (33%)
		ORANGE	115..162	CDD:128787	17/52 (33%)
		Atrophin-1	<136..311	CDD:331285	36/159 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	239..308		8/44 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740