DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sidpn and Hes3

DIOPT Version :9

Sequence 1:	NP_523599.1	Gene:	Sidpn / 35168	FlyBaseID:	FBgn0032741	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_011248491.1	Gene:	Hes3 / 15207	MGIID:	104877	Length:	291	Species:	Mus musculus

Alignment Length:	198	Identity:	53/198 - (26%)
Similarity:	84/198 - (42%)	Gaps:	47/198 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SKNKSAPGIGFTAAGSTNGSGIKSIGLVSSTQNVTSSQDISKRTNKPLMEKRRRARINQSLAILK 74
            |.::....:...||...:|. :|.:|:                 :||||||:||||||.||..|:
Mouse    87 SPHRGTASVAQPAASERSGV-LKGMGI-----------------SKPLMEKKRRARINVSLEQLR 133

  Fly    75 ALILESTKTQNAKNGEGQAKHTKLEKADILELTVRHFQRHRNLDD--------PTVNKYRAGYTD 131
            :|:        .::...|.:..||||||||||:|::.   |:|.:        |:...|.:|:..
Mouse   134 SLL--------ERHYSHQIRKRKLEKADILELSVKYM---RSLQNSLQGLWPVPSGVDYPSGFQG 187

  Fly   132 CAREVARYLATPEPPPMGTMPTLAE-------PGSKARLLRHLDQCIAEIDVEICPHSTAAFAES 189
            ..|.|::.|...|.......|.|.:       ..:..:....|:.|:..|   ..|...|..:.|
Mouse   188 GLRGVSQRLRPGEGDSGLRCPLLLQRREGSTTDSANPQATSVLNPCLPAI---WAPSRAAGGSHS 249

  Fly   190 PSS 192
            |.|
Mouse   250 PQS 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sidpn	NP_523599.1	HLH	48..117	CDD:238036	29/68 (43%)
Sidpn	NP_523599.1	Hairy_orange	125..172	CDD:284859	10/53 (19%)
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	27/64 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910