DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31792 and YKR104W

DIOPT Version :9

Sequence 1:	NP_001260548.1	Gene:	CG31792 / 35163	FlyBaseID:	FBgn0051792	Length:	1323	Species:	Drosophila melanogaster
Sequence 2:	NP_013030.1	Gene:	YKR104W / 853979	SGDID:	S000001812	Length:	306	Species:	Saccharomyces cerevisiae

Alignment Length:	312	Identity:	134/312 - (42%)
Similarity:	193/312 - (61%)	Gaps:	29/312 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1021 MISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKP 1085
            |.||||:.||.:|    |.|:.....|..:||:.|.:|...|||||.|:  |...|.::||.:|.
Yeast     1 MSSVERIKEYTDI----PSESNGYISPPANWPQTGDVELKNLSLRYSPH--SSKALDNVSFKVKA 59

  Fly  1086 KEKVGIVGRTGAGKSSLINALFRLS-YNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTV 1149
            ..||||||||||||||:|.|::||| :.:|::.||:||...:.|..||:.||.|||:|.||.|||
Yeast    60 GTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIPLERLRNSISCIPQDPTLFDGTV 124

  Fly  1150 RHNLDPFDEYSDDRLWCALEEVELKDVVASVA-------------------TGLETKITEGGSNF 1195
            |.||||||.|||.:::..|.:|.|.:....:.                   ..|.|.:..||||.
Yeast   125 RSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFEQEQPNFSSHKLRNRFIDLNTVVKSGGSNL 189

  Fly  1196 SVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSD 1260
            |.|||||:||||::|....|:::|||||::|..:||.||.|||...:..|:||:||||.:::|.|
Yeast   190 SQGQRQLLCLARSMLGARNIMLIDEATASIDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYD 254

  Fly  1261 RVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQATYDTLLKISQREFE 1312
            ::|||:.|||.|:..||.|: :|....|..|.:|:|:  ::.|.::::..|:
Yeast   255 KILVMEMGRVKEYDHPYTLI-SDRNTIFYRLCRQSGE--FENLFELAKVSFD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	127/279 (46%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217
		ABC_membrane	736..980	CDD:294371
		ABCC_MRP_domain2	1055..1276	CDD:213211	111/240 (46%)
YKR104W	NP_013030.1	ABCC_NFT1	27..270	CDD:213269	113/244 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740