DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31792 and NAP5

DIOPT Version :9

Sequence 1:	NP_001260548.1	Gene:	CG31792 / 35163	FlyBaseID:	FBgn0051792	Length:	1323	Species:	Drosophila melanogaster
Sequence 2:	NP_177289.1	Gene:	NAP5 / 843474	AraportID:	AT1G71330	Length:	324	Species:	Arabidopsis thaliana

Alignment Length:	328	Identity:	103/328 - (31%)
Similarity:	157/328 - (47%)	Gaps:	41/328 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 MDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPLS 587
            |||.|||.|:..|:|.:|.|:|...|:|::|:||.:||||||.||.:||::|:||.|||.|||.|
plant     1 MDRERYDKVIEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIHIARALYQDADIYLFDDPFS 65

  Fly   588 AVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDF- 651
            |||:.....||:|.|||.|..|.||.||||::||..||..::|:.|::...|.|..:..||.||
plant    66 AVDAHTGSHLFKEALRGLLCSKSVIYVTHQVEFLPSADLTLVMKDGRISQAGKYNDILISGTDFR 130

  Fly   652 -------------GIVLDDPVNDNEAAEDRSRTSSITDQRRSSVKSVLSHAESCPEDVGEEQKIN 703
                         |......|::|.|.::.:  ..:.|......|......::...|.||.|:..
plant   131 ELIGAHQESLAVVGSADASSVSENSALDEEN--GVVRDDIGFDGKQESQDLKNDKLDSGEPQRQF 193

  Fly   704 LQRQQ--LGRNGLGVYVDYFR-AGGGFLSFSVVMTFFVCSQ---GLASLGDYFLSPWVSRNEKMV 762
            :|.::  .|...|.||..|.. |.||.|     :.|.:..|   .|..:|..:...|.
plant   194 VQEEERAKGSVALDVYWKYITLAYGGAL-----VPFILLGQILFQLLQIGSNYWMAWA------- 246

  Fly   763 AHNYTTDAKDADFEMHAA---YIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRAS 824
                |..::|....:..:   .:|:.:...|.:..:.|:.|......:.:.:|.:.|...|.|:.
plant   247 ----TPISEDVQAPVKLSTLMVVYVALAFGSSLCILVRATLLVTAGYKTATELFHKMHHCIFRSP 307

  Fly   825 MYF 827
            |.|
plant   308 MSF 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	103/328 (31%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217	59/110 (54%)
		ABC_membrane	736..980	CDD:294371	17/98 (17%)
		ABCC_MRP_domain2	1055..1276	CDD:213211
NAP5	NP_177289.1	P-loop_NTPase	<1..112	CDD:304359	59/110 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	99	1.000	Domainoid score	I2369
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910