Protein Alignment CG31792 and Abcc6

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_112275.1
• Gene: Abcc6 / 81642
• RGDID: 620268
• Length: 1502
• Species: Rattus norvegicus
• Alignment Length: 1372
• Identity: 439/1372 - (31%)
• Similarity: 691/1372 - (50%)
• Gaps: 145/1372 - (10%)

  Fly     4 FKNEDLPEN--PRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWA 66
            |..:..|.|  |...::..|...||:......||.:..||.|||:...:|:.:|.|.::|...|.
  Rat   199 FSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWR 263

  Fly    67 ---NELETNK-------------------KNASLLRVLFRVFGRYFVFLGLVLFCLEVILTVQPM 109
               :||..:|                   :...|||.::|||...|:...|.|...:......|.
  Rat   264 RNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPK 328

  Fly   110 FLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCL 174
             |:.|...|.....:|....:..|..:.|.:.|:.:....|.:.|..|.:::|..::.::|||.|
  Rat   329 -LLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVL 392

  Fly   175 RLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFI 239
            .|:.......:.|.::||:|.|:.|:...|...:.|||..|..::....::|.:|.:|:..:...
  Rat   393 VLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVF 457

  Fly   240 LLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINS 304
            |..:||..::.||.|..:.:...:...|.|:.:.::..::.||.:.||..|.:.:.|.|.:|:.:
  Rat   458 LSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGA 522

  Fly   305 IRHVAYAKCLIWSFNRFLTPVSIFL-SLVGF-----VLMGRFLTAEVAFLITAYYNVVRTNMTAY 363
            ::..|:    ::|.:.....||.|| :||.|     |.....:.||.||:.....::: ....|:
  Rat   523 LKTSAF----LFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSIL-NKAQAF 582

  Fly   364 FSVGVTQTAETLVSIKRVQKLLLSGEVVAKDENVVSNGAEEDLQEAREKLLVTPTPMRAPEKPPH 428
            ....|....:..||..|:...|..       |.|..||             :..:|.|.
  Rat   583 LPFSVHCLVQARVSFDRLAAFLCL-------EEVDPNG-------------MVLSPSRC------ 621

  Fly   429 NSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEI 493
            :|:|.:||......|:..||. .|.|:||.|..|.|:|:||..|:|||||:.|:||||....|.:
  Rat   622 SSKDRISIHNGTFAWSQESPP-CLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSV 685

  Fly   494 EVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGAS 558
            .:.||::|..||.|:.:.:|.:|:.|.|.:|......|:..|||..|....|....|.:|::|.:
  Rat   686 SIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMN 750

  Fly   559 LSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECL--RGHLRDKIVILVTHQLQFL 621
            ||||||.|:||||:|||.|::||:||||:|:|:.|::.:|::.:  .|.|:....|||||.|..|
  Rat   751 LSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVL 815

  Fly   622 QQADQIVIMEMGKVKAVGTYES-LHKSGLDFGIVLD---DPVNDNEAAEDRSRTSSI-------- 674
            .|||||:::..|.:..:|:|:. ||::|...|: ||   .|..:.|.....:.||..
  Rat   816 PQADQILVLANGTIAEMGSYQDLLHRNGALVGL-LDGARQPAGEGEGEAHAAATSDDLGGFSGGG 879

  Fly   675 TDQRR---------SSVKSVLSHAESCP--EDV-------GEEQKINLQRQQLGRNGLGVYVDYF 721
            |..||         :.||...|.|:..|  :||       ||:.      .|.||.....|:.|.
  Rat   880 TPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDS------VQYGRVKSATYLSYL 938

  Fly   722 RAGGGFLSFSVVMTFFVCSQGLASLGDYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAAYIYMLI 786
            ||.|..|. :..:..|:|.|..:....|:||.|        |.:...|.|    :||:|....:.
  Rat   939 RAVGTPLC-TYTLFLFLCQQVASFCQGYWLSLW--------ADDPVVDGK----QMHSALRGSIF 990

  Fly   787 TVLSIMVTIKRSFLFFNLA------MRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMG 845
            .:|..:..|.   ||.::|      .|||..|..|:...::|:.:.||.:.|.|::||||||:..
  Rat   991 GLLGCLQAIG---LFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETD 1052

  Fly   846 QVDEMLPTIIMTVIQDFLLFG----GNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKR 906
            .||..:|..:.|::.  ..||    |  :.:::..||.::..|...::....:|.|:.|...::|
  Rat  1053 IVDVDIPDKMRTLLT--YAFGLLEVG--LAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRR 1113

  Fly   907 LEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIF- 970
            ||:::.|.|.||.|.:..|...:|||.|.....|:.|...|.:...|:..:...|..|..:::.
  Rat  1114 LESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLG 1178

  Fly   971 -CVLFIAMITLSFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIE 1034
             .::|:| .|.:.......||...|.:::.|:.:|.|:||.||...:|||:|::|||:.:|....
  Rat  1179 NGLVFVA-ATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTP 1242

  Fly  1035 PEGP--LEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGA 1097
            .|.|  |.::|   ....||..|:|||.:..||:.|.|  ...::.:|..|...|||||||||||
  Rat  1243 KEAPWRLPSSA---AQPLWPCGGQIEFRDFGLRHRPEL--PMAVQGVSLKIHAGEKVGIVGRTGA 1302

  Fly  1098 GKSSLINALFRL-SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSD 1161
            |||||...|.|| ...:|.:.||.....|||||.|||:|:||||:||||.|::|.|||...|.:|
  Rat  1303 GKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTD 1367

  Fly  1162 DRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVD 1226
            :.:|.|||.|:||..|.|:...|:.:.:..|.:.||||:||:|||||:||..:||::|||||:||
  Rat  1368 EGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVD 1432

  Fly  1227 PQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDL 1291
            |.|:..:||.:...|.:||||.:||||.::|:..||||||.|:|.|.|:|.:||.  ....|..|
  Rat  1433 PGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLA--QKGLFYRL 1495

  Fly  1292 VKQTGQA 1298
            .:::|.|
  Rat  1496 AQESGLA 1502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	438/1369 (32%)
Abcc6	NP_112275.1	MRP_assoc_pro	36..1501	CDD:188098	437/1369 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	854..909		12/54 (22%)