Protein Alignment CG31792 and Abcb8

DIOPT Version :9

• Sequence 1: NP_001260548.1
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_083296.2
• Gene: Abcb8 / 74610
• MGIID: 1351667
• Length: 717
• Species: Mus musculus
• Alignment Length: 554
• Identity: 130/554 - (23%)
• Similarity: 242/554 - (43%)
• Gaps: 60/554 - (10%)

  Fly   792 MVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIM 856
            ::|.....|..::..|.::.:..::|..:.|..:.||:....|.:::|.:.|:.:.......:|.
Mouse   189 LLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVIS 253

  Fly   857 TVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAA 921
            ..::......|:::.:::::|..   .|...:|...|..........:::|....:..:......
Mouse   254 QGLRSCTQVIGSLVSLSMLSPRL---TLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGV 315

  Fly   922 SLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIFCVLFIAMITLSFFIFP 986
            :...|..:|...|.::.:.|.:.||....|.........|..|.:..:..:.|..|:..:.||
Mouse   316 ADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFI-- 378

  Fly   987 PSSAADVGLAITQAMGLTG-----------TVQWTVRQSAELENTMI----SVERMIEYEEIEPE 1036
                   |.::.....|.|           |||.::...:.|...::    :..|:.||..:.|.
Mouse   379 -------GGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPV 436

  Fly  1037 GPLEA-----TADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTG 1096
            .||..     ..|.:        |.|.|..::..| |.....:|||..:..:...:.|.:||::|
Mouse   437 IPLTGGYCIPNKDIR--------GSITFQNVTFSY-PCRPGFNVLKDFTLKLPSGKIVALVGQSG 492

  Fly  1097 AGKSSLINALFRLSYND--GSVRIDDKDTNDMGLHDLRSK-ISIIPQEPVLFSGTVRHN-----L 1153
            .||:::.:.|.|. |:.  |||.:|..|...:....||.: |..|.||||||:.|:..|     |
Mouse   493 GGKTTVASLLERF-YDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKL 556

  Fly  1154 DPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVM 1218
            |.    ||:.::.|..|....:.::|...|..|.:.|.|:..|.||:|.:.:|||:::...:|::
Mouse   557 DA----SDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLIL 617

  Fly  1219 DEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTAD 1283
            ||||:.:|.:::.::|..:.......|||.:||||.|:..:..::||..|:|.|.||..|||...
Mouse   618 DEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKG 682

  Fly  1284 DTNAFQDLVKQTGQATYDTLLKISQREFEKSEKP 1317
              ..:.:|::   :.|.|..| .|....||.|.|
Mouse   683 --GLYSELIR---RQTLDASL-TSTPPAEKPEDP 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	120/516 (23%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217
		ABC_membrane	736..980	CDD:294371	28/187 (15%)
		ABCC_MRP_domain2	1055..1276	CDD:213211	73/228 (32%)
Abcb8	NP_083296.2	MdlB	116..695	CDD:224055	123/536 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	695..717		7/17 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000