Protein Alignment CG31792 and abcc8

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: XP_005170744.1
• Gene: abcc8 / 553281
• ZFINID: ZDB-GENE-050517-22
• Length: 1594
• Species: Danio rerio
• Alignment Length: 1422
• Identity: 435/1422 - (30%)
• Similarity: 709/1422 - (49%)
• Gaps: 212/1422 - (14%)

  Fly    18 NIFSALSFWYTIPTFI------------------------------------KGQKVT--LGAKD 44
            |:.|..::|: :.|||                                    ||.:.|  .|:|.
Zfish   236 NLLSKSTYWW-MNTFITSAHRRPIDLKVIGRLPIAMRALTNYIKLRQAFEAQKGPQDTPPQGSKW 299

  Fly    45 LYRALKEHRAESLGNKLCSSWANELETNKKNASLLRVLFRVFGRYFVFLGLVLFCLEVIL----- 104
            ::.||:    ::.|..|                :|.:.:|.......|.|.:  |:..|:
Zfish   300 IWAALR----QAFGKPL----------------ILSITYRFMADLLGFAGPL--CISGIVHHLSK 342

  Fly   105 ---TVQPMFL---MKLISSFSNPSPTSNGVAYAYAGGVILGSAL---KVILMNPYSFAVTHLGLK 160
               |:.|...   |..|||       ...:|..|...|:|..||   :..|...|..|: ..|:.
Zfish   343 ENHTILPPVKHLGMYFISS-------QEFLANGYVLAVLLFFALLLQRTFLQASYYVAI-ETGIN 399

  Fly   161 IRVGVSSMIYRKCLRLTKTDL--GEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYL 223
            :|..:.:.|:.|.:||..::|  |.::.|.|.||::.|..::..|......|:..|:|.::...|
Zfish   400 LRGAIQTKIFNKIMRLCTSNLSMGGMTVGQICNLVAIDTNQLMWFFFLCPNLFAMPVQIIVGIIL 464

  Fly   224 MYQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWEL 288
            :|..:||:|:.|.|.|.|..|:|.::..|:|..:..|...|.:|::...|::.||:::|:||||.
Zfish   465 LYYLLGISALIGATIITLLAPVQYFVATKLSDAQKSTLEYSSERLKKTNELLRGIKLLKLYAWEH 529

  Fly   289 PFEKMVAHARHKEINSIRHVAYAKCLIWSFNRFL-TPVSIFLSLVGFVLMGRF-----LTAEVAF 347
            .|...|...|.||:.|::  |:|  |..|.:.|: |.:.|...||.||.....     |:..|||
Zfish   530 IFCSNVEETRCKELTSLQ--AFA--LYTSISIFMNTAIPIAAVLVTFVAHVHLSDDADLSPAVAF 590

  Fly   348 LITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDE---NVVSNGAEEDLQEA 409
            ...:.::::.|.:....|| |..|.:.|||::::.:.....|:..:.|   .||.|....:..:|
Zfish   591 ASLSLFHILVTPLFLLSSV-VRSTVKALVSVQKLSEFFSCDEIGGEQEPRATVVPNSTNHNKYQA 654

  Fly   410 REKLLVTPTPMRAPEKPPHNS----------------ED-CVSISELKAKWTTNSPDYTLSGVNL 457
            ....:|.   .:.|.:...||                || |:.|:.....||..:.  |||.||:
Zfish   655 LPLKVVN---RKRPVREDWNSFALQSEQEDEVLAVGDEDICIKITNGYFSWTEGTS--TLSNVNI 714

  Fly   458 QVHAGALVAIVGHTGSGKSSLIQAILGELR-------------------------VESGEIEVTG 497
            ::..|.|..|||..|.|||||:.|.|||::                         ...|:|...|
Zfish   715 KIPFGQLTMIVGQVGCGKSSLLLAALGEMQKISGTVIWNRMPTLDAEGNESLPDAAAEGDIRKRG 779

  Fly   498 SMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGG 562
            :::||||:|||.:.|:.:||.|..|:.::||..|:..|:|:.|.::||..|:||:|:||..||||
Zfish   780 AVAYASQKPWLLNTTLAENITFEMPLIKQRYRAVIEACSLQPDIDILPQGDQTIIGERGIILSGG 844

  Fly   563 QKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHLRD--KIVILVTHQLQFLQQAD 625
            |:.|||:||::|:..::..||||.||:|..::..|.:|.:...||:  :.|::|||:||:|..||
Zfish   845 QRQRISVARALYQTTNVVFLDDPFSALDIHLSDHLMQEGILKLLREEKRTVVIVTHKLQYLPHAD 909

  Fly   626 QIVIMEMGKVKAVGTYESLHKS----------------------GLDFGIVLDDPVNDNEAAEDR 668
            .|:.|:.|.::..||.:.:.||                      .:|..:.:.:..|...|...|
Zfish   910 WIIAMKDGSIQTEGTLKDIQKSQPELFEQWKTLMHRQDKEFEKETVDENMTVLERKNLRRAMYSR 974

  Fly   669 SRTSSITDQRRSSVKSVLSHAESCPEDVGEEQKINLQRQQLGRNGLGVYVDYFRAGGGFLSFSVV 733
            ....:..|:...|::|         :|.....::...|..:.....|.|:    :..|.|...::
Zfish   975 EALKTEEDEEEESLES---------DDDDNLSQVMRHRATIPWRSCGTYL----SSAGLLLLLLL 1026

  Fly   734 MTFFVCSQGLASLGDYFLSPWVSR--NEKM--VAHNYTTDAKDADFEMHAAY--IYMLITVLSIM 792
            :...:....|....||:|:.|.|:  ..|:  .|||.:. .:|..| .|::|  ::.|:..|.|:
Zfish  1027 LLSQLLKHSLLVAIDYWLAHWTSKVITAKIDAAAHNCSL-VQDIGF-THSSYLLVFSLLCCLGIV 1089

  Fly   793 VTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMT 857
            :.:..|.......:|.:.:||:::...|..|.|..|...|.||||||||.|...:|:.:|..:..
Zfish  1090 LCLATSVAVEWTGLRVAKELHHNLLSNIILAPMRLFETTPLGSILNRFSSDTNTIDQHIPATLEC 1154

  Fly   858 VIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAAS 922
            :.:..||....:.||:.|.|:|||......|..|:::.::...|.|:::||.||:.|:.|||:.:
Zfish  1155 LSRSTLLCVSALGVISYVTPVFLIVLAPLTIACYFIQKYFRVASKDLQQLEDSTQLPLLSHFSET 1219

  Fly   923 LNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDI------FCVLFIAMI-TL 980
            :.||:|||||............:.|.::.||....:.:|    |:::      .|::.||.: ::
Zfish  1220 VEGLTTIRAFRYEPRFRQRLLQFTDANNMASLFLTAANR----WLEVRMEYIGACIVLIAAVASI 1280

  Fly   981 SFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEP---EGPLEAT 1042
            :..::...|...|||.:|.|:.::..:.|.||..|::|..:.:|:|:......||   ||.|.|:
Zfish  1281 TNSLYSHLSTGLVGLGLTYALMVSNYLNWMVRNLADMEVQLGAVKRIKALLRTEPENYEGLLSAS 1345

  Fly  1043 ADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALF 1107
               :..|.||:||:|:...||:||:..||  .|||.::..|||.:|:||.||||:||||...|.|
Zfish  1346 ---QVPEGWPQQGEIQIQNLSVRYDSTLK--PVLKHVNAHIKPGQKLGICGRTGSGKSSFSLAFF 1405

  Fly  1108 RL-SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALEEV 1171
            |: ...:|.:.|||.|...:.|..|||:.|||.|:|.|||||:|.||||..:.:|..||.|||..
Zfish  1406 RMVDTFEGRIIIDDIDIAKLPLQTLRSRFSIIQQDPFLFSGTIRFNLDPEMKATDSMLWEALEIA 1470

  Fly  1172 ELKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQAT 1236
            :||.||.::..||:..|||||.|||.|||||.|||||.:|.:.||:||||||::|..|::::|..
Zfish  1471 QLKPVVKTLPGGLDAIITEGGENFSQGQRQLFCLARAFVRKSSILIMDEATASIDMATESILQKV 1535

  Fly  1237 IRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVK 1293
            :...|.:.||:|:|||:|||:::|.|:||..|.::||..|..||..:| :.|...|:
Zfish  1536 VMTAFADRTVVTIAHRVHTILNADLVIVMKRGVILEFDKPEVLLDQED-SVFASFVR 1591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	435/1422 (31%)
abcc8	XP_005170744.1	MRP_assoc_pro	39..1591	CDD:188098	434/1420 (31%)