Protein Alignment CG31792 and Mrp5

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_001262747.1
• Gene: Mrp5 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Alignment Length: 1340
• Identity: 773/1340 - (57%)
• Similarity: 997/1340 - (74%)
• Gaps: 43/1340 - (3%)

  Fly     1 MQSFKNEDLPENPRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSW 65
            |||.|.::|||||||:|||||:|.|.:.:|||.||:|.||...||||||:|||::.||:||.::|
  Fly     1 MQSMKADELPENPREKSNIFSSLMFCFAMPTFFKGRKKTLDENDLYRALQEHRSDHLGSKLSAAW 65

  Fly    66 ANELE---TNKKNASLLRVLFRVFGRYFVFLGLVLFCLEVILTV-QPMFLMKLISSF---SNPSP 123
            ..|:|   ..||..|||:....|||.....||||||.||:...| ||:||..|::.:   ||...
  Fly    66 EKEVEKKRKKKKTPSLLKASMNVFGWRLAGLGLVLFILEIGFRVTQPLFLGGLVAYYADASNQEG 130

  Fly   124 TSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGH 188
            .:...||.||.||||.||..|:.|:||...:.|:|:|.|:.::||||||.|||::|.||:.:.|.
  Fly   131 DNQTKAYLYALGVILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALGDTTIGQ 195

  Fly   189 IINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFILLFIPLQMYLGKKI 253
            ::||||||:||:|..:...:||||.|::..::|||||:||||:|.||:..:|||||||.|||||.
  Fly   196 VVNLISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKT 260

  Fly   254 SGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLIWSF 318
            |.||||||:|:|:|:|:|.|||:|||||||||||:||.||:.:.|.||:|:||:|.|.:..:.||
  Fly   261 SVLRLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSF 325

  Fly   319 NRFLTPVSIFLSLVGFVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQK 383
            ..|:|.:|:|:|||||||:|:.||||.||:||||||::|..||.||.:|::|.||.||||:|:|.
  Fly   326 IMFVTRISVFVSLVGFVLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQT 390

  Fly   384 LLLSGEVVAKDENVVSNGAEEDLQE---AREKLLVTPT------PMRAPEKPPHNSEDCVSISEL 439
            .:|..|...:|::       |||.|   .:..|:..||      .::...:....:|..:.||:|
  Fly   391 FMLHEETKVRDKS-------EDLDEQKLGKAGLIAEPTVAQTTGVLKPSSRRTSEAEHSIVISKL 448

  Fly   440 KAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQ 504
            ||||...:.|.||..::|:.....|||::|..||||||||||:||||..:||.::|.|::|||||
  Fly   449 KAKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSVKVNGTLSYASQ 513

  Fly   505 EPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISL 569
            |||||:||||||||||.|||:.||..||::|||||||||||..||||:|:|||||||||||||||
  Fly   514 EPWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGGQKARISL 578

  Fly   570 ARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEMGK 634
            ||:|||.|.||||||||||||:.|.|.||::|:||.||::||:|||||||||:|||.||||:.||
  Fly   579 ARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVIVIMDKGK 643

  Fly   635 VKAVGTYESLHKSGLDFGIVLDDPVNDNEAAEDR------SRTSSITDQRRSSVKSVLSHAESCP 693
            :.|:|||||:.||||||..:|.||...:|.|.|.      ||.:|....|..|:.|:    ||..
  Fly   644 ISAMGTYESMAKSGLDFAQMLTDPSKKDEGAGDAPDKKSLSRQNSKLRDRHGSISSM----ESAA 704

  Fly   694 EDVGEEQKINLQRQQL-GRNGLGVYVDYFRAGGGFLSFSVVMTFFVCSQGLASLGDYFLSPWVSR 757
            |.:..|..:..|..:: ||.|:.:|..||.|.|..| |.|...|.:.:|.|||.||.|||.||::
  Fly   705 ESLAAESPMQTQEGRVEGRIGMKLYKKYFGANGYGL-FIVFAFFCIGAQVLASGGDIFLSYWVNK 768

  Fly   758 NEKMVAHNYTTDAK--------DADFEMHAAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHN 814
            |.:.....:....:        :||.:....|.:..|.|..|:.::.||.|||.||||:|..|||
  Fly   769 NGEAERDTFMARLRRAFPETRINADTDPVDIYYFTGINVSVIIFSLVRSMLFFYLAMRSSTTLHN 833

  Fly   815 SMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLF 879
            :||:|::||:|:|||.||:|.||||||||:|||||:||:::|.|:|.||...|.::|:.|:|..:
  Fly   834 TMFQGVTRAAMHFFNTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLAIVGIVVVLCIINVWY 898

  Fly   880 LIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDG 944
            ::..:...||.|.||.|||.||.|||||||.||||:|||.:||||||:|||||||...|.||||.
  Fly   899 ILATVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGLATIRAFGAQKELIAEFDN 963

  Fly   945 YQDMHSSASYMFISTSRAFAYWMDIFCVLFIAMITLSFFIFPPSSAADVGLAITQAMGLTGTVQW 1009
            |||||||..|||::|||||.||:|..||::||:||||||:|.|.:..|||||||||||:||.|||
  Fly   964 YQDMHSSGYYMFLATSRAFGYWLDCVCVVYIAVITLSFFLFSPENGGDVGLAITQAMGMTGMVQW 1028

  Fly  1010 TVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSES 1074
            .:||||||||||.:|||::|||::||||..|:..:|||.:.|||.|||.|.:|||:|.|...::.
  Fly  1029 GMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKKPPKDWPEDGKIVFDDLSLKYFPDKAADY 1093

  Fly  1075 VLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYNDGSVRIDDKDTNDMGLHDLRSKISIIP 1139
            ||:||:..|:..||||||||||||||||||||||||||:|::.||.:||||:|||||||||||||
  Fly  1094 VLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLSYNEGAILIDRRDTNDLGLHDLRSKISIIP 1158

  Fly  1140 QEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVC 1204
            |||||||||:|:||||||||||.:||.:||||:||.|||.:.:||::||:|||:|||||||||||
  Fly  1159 QEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQVVADLPSGLQSKISEGGTNFSVGQRQLVC 1223

  Fly  1205 LARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGR 1269
            |||||||:||||||||||||||||||||||.||||||::|||||:||||||:||||:|||||||:
  Fly  1224 LARAILRENRILVMDEATANVDPQTDALIQTTIRNKFKDCTVLTIAHRLHTVMDSDKVLVMDAGK 1288

  Fly  1270 VVEFGTPYELLTADDTNAFQDLVKQTGQATYDTLLKISQR 1309
            .||||:|:||||..:...|..:|||||.:|:|.|||::|:
  Fly  1289 AVEFGSPFELLTTSEKKVFHSMVKQTGDSTFDALLKVAQK 1328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	769/1334 (58%)
Mrp5	NP_001262747.1	MRP_assoc_pro	79..1315	CDD:188098	721/1247 (58%)