Protein Alignment CG31792 and Sur

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: XP_061511301.1
• Gene: Sur / 3292067
• VectorBaseID: AGAMI1_003204
• Length: 2282
• Species: Anopheles gambiae
• Alignment Length: 1601
• Identity: 394/1601 - (24%)
• Similarity: 642/1601 - (40%)
• Gaps: 524/1601 - (32%)

  Fly   187 GHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFG-MTFILLFIPLQMYLG 250
            |.|.||:|:|...:.:|::..||:|..||:..:|.||:|:::||:.|.| :..|:...|||:.:|
Mosquito   699 GTITNLMSDDAFNVMSFVKMVHYVWAIPLKIAVVMYLLYRQLGISTVIGSVVCIVTMTPLQLLIG 763

  Fly   251 KKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLI 315
            |.::....|.:..:|:|:|.:.|::.||::||:.|||..|:..::.||.:|   :||:. ...:.
Mosquito   764 KLMAANSKKVSECTDERLRRINEVLLGIKLIKLNAWETVFKDKISQARQQE---LRHLD-LDSIY 824

  Fly   316 WSFNRFLTPVS----------IFLSLVGFVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQ 370
            |:....||.:|          :||:|....:.   |||...|...|.:|.: |.....|.:.:..
Mosquito   825 WTLMMLLTHISSVLITIVTIAVFLALENNPIE---LTAGRLFASLALFNQL-TVPLFIFPITIPI 885

  Fly   371 TAETLVSIKRVQKLLLSGEV--------------------------------------------- 390
            |...:||..|::..|...||
Mosquito   886 TLSAIVSTGRLEAFLGQPEVERSSLEGIRTMARILSKSDASLDMDEAGDPQYGDDAAAAQEQCPG 950

  Fly   391 --------------------VAKDENVVSNGAEEDLQEAREKLLVTPTPM--------------- 420
                                :...:||  .|:.:..::|.:.  ..|.|:
Mosquito   951 VPVVAPPDQVEEGQQLQQPGIKSSDNV--TGSPQTERKAADN--AGPLPLVEDVGGKSCSQHSSM 1011

  Fly   421 ------------RAP------------------------------------EKPPHNSED----- 432
                        |||                                    :|..|.:.:
Mosquito  1012 SSDRSIRCEQVDRAPMARQRPAKYQKTVPSPRVKLKKHSQLSVSARLEKCRQKQKHLAREMRFGL 1076

  Fly   433 ----CVSISELKAKWTTNSPDYTLSGV-----NLQVHAGALVAIVGHTGSGKSSLIQAILGELRV 488
                .|.:.:.:.:|.....|.|::..     .|.|....|..|||.:|||||||:.|:|.|:..
Mosquito  1077 PDHAAVFLKDARFRWNDTGADDTMAHCALHIEQLTVPKAKLTVIVGRSGSGKSSLLAALLKEINH 1141

  Fly   489 ESGEI--EVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTI 551
            .|||:  ....|::|..|:|||.:.|:|:|:|||:....:|||.|:|.|||:.|.:|:|..|.|.
Mosquito  1142 LSGELIWNKYSSIAYVPQKPWLQNATIRENVLFGESFRPKRYDRVLRACALKPDLDLMPAGDGTE 1206

  Fly   552 LGDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHL--RDKIVILV 614
            :|:||..|||||:.||::||::|..|::.:|||||||:|:.||..:||..:...|  :.:.:|||
Mosquito  1207 IGERGLKLSGGQRQRIAIARALYSSANVVILDDPLSALDNEVAMDVFENGVHRMLARQKRTIILV 1271

  Fly   615 THQLQFLQQADQIVIMEMGKVKAVGTYESLHK--------------------------------- 646
            |.::|.:.:||.||:||.|.|.|.|:...:..
Mosquito  1272 TQKVQLVHRADNIVVMEGGTVSATGSLTEIENNYPHILREWNAIIAKEQQQSSEAQSSPGRTARE 1336

  Fly   647 ---------------------------------------------SGLDFGIVLDD--------- 657
                                                         |..||.:.::|
Mosquito  1337 RWKLFKNISRISFQRNHATEENDFMERTFYFPRTMANRALFGSRFSAHDFPLPIEDCHEPNVALR 1401

  Fly   658 --------------------------------------------------------PVNDNE--- 663
                                                                    .||..:
Mosquito  1402 RHYSNRLRKDSPPSSTAVVLRRPPLGQIEHPPGTGHQSVFRALSLQLGTNATTSSSTVNQRQQRQ 1466

  Fly   664 ----------------------------------------------------------------- 663
                                                                             
Mosquito  1467 PAVVVRHISFPTTLTSSGALDDDTLYRKRLNQGGTAAHPGQLASAGALSGQRRMLASTDDTGMDG 1531

  Fly   664 ------------------AAEDRSRTS-------------------------------------- 672
                              :.||..|:|
Mosquito  1532 IEPNRTGVLLYGQNEGRNSCEDLKRSSIGFRIPEFLRRMSLRGRRFSNPTEFGRPYREREDGSRK 1596

  Fly   673 ---------SITDQRRSSVKSVLS-------HAESCPEDVGEEQKINL----QRQQLGRNGLGVY 717
                     ||..:|..|:|.:||       ..|....|.||.:..|.    ..::.||....:|
Mosquito  1597 SSRKTSSLKSIPKERHYSIKRLLSTISRQSEDTEESSVDYGEAEVSNRLIYDDERKYGRIPARMY 1661

  Fly   718 VDYFRAGGGFLSFSVVMTFF---VCSQGLASLGDYFLSPWVSRNEKMVAHNYTTDAKDAD----- 774
            ..|..:.|.    .:|..||   :..|.|....|::|..|..:...:......|:...||
Mosquito  1662 WLYLISCGP----RMVAIFFLSALAQQALKVYTDFWLQEWTDQTATISTIVVPTNGTVADASSPT 1722

  Fly   775 --------FEMHAAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKN 831
                    |..:.|...:.|.:.:|.|...:     .....|..:||..:...:.:.|::||...
Mosquito  1723 KPLEIRRHFHAYVALSAVCIVLAAISVPAGQ-----RAGSNARRRLHRELIASVLQNSIHFFQSV 1782

  Fly   832 PAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSF 896
            |.|.|:||.|.|:..||:.:......::|..||....:::.::|.|.|::..:....:.|.::.|
Mosquito  1783 PLGRIMNRLSIDVAVVDKKIAATSQKLLQFILLCVCAVLINSVVTPYFILLTIPICGIYYMVQKF 1847

  Fly   897 YLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEF----------DGYQDMHSS 951
            |..:|.:::|:|:.|.|||.:||:.::.|::||||||.    ||.|          :....:..:
Mosquito  1848 YRASSRELQRIESMTYSPVLAHFSETIEGVTTIRAFGQ----EARFMEVLFKRMEANNVAQLALN 1908

  Fly   952 ASYMFISTSRAFAYWMDIFCVLFIAMITLSFFIFPPSSAAD-VGLAITQAMGLTGTVQWTVRQSA 1015
            .|..::..:..:...:.:|..:..|:||.|  :.|.|:::. :|||:..||.:...:.|.|:..|
Mosquito  1909 CSNRWLGIALDYLGAIIVFVAILTALITAS--LRPQSTSSSLIGLAVNYAMLVPIYLNWVVKLFA 1971

  Fly  1016 ELENTMISVERMIEYEEIEP-----EGPLEATADKKPHE-------------SWPEQGKIEFVEL 1062
            |:|....:|||:..:.|.:.     :|.|...:.:...:             |||.:|.|.:..:
Mosquito  1972 EMEMYGGAVERIQSFIECDVQRRRLDGGLRGRSSRVVQDTGVVPFSYKTVPISWPLRGVIVYEGV 2036

  Fly  1063 SLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALF-RLSYNDGSVRIDDKDTNDM 1126
            |||||.  :.|:::.:|:..|...:::||.||||:|||||..||| .|....|.:.|||.|.  .
Mosquito  2037 SLRYEN--QKENIITNLNLTIPAGQRLGICGRTGSGKSSLALALFGALEITAGRILIDDVDI--A 2097

  Fly  1127 GLH--DLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLETKIT 1189
            |||  :|||::||||||.:||.|:||.||||...:||..||..||..:||:||.|:..||:|:|:
Mosquito  2098 GLHTDELRSRLSIIPQEVMLFGGSVRENLDPRGHFSDLELWNCLELAQLKNVVMSLPDGLDTQIS 2162

  Fly  1190 EGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLH 1254
            :....||.|||||.||||||||.:..||:||||:::|.:|:.|:....:..|:..||:|:|||||
Mosquito  2163 DDKHYFSSGQRQLFCLARAILRGSVCLVLDEATSSLDTETEKLVLQAAKKAFKGRTVITIAHRLH 2227

  Fly  1255 TIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQT 1295
            :::|.:||||::.||:||.|.|.: |.....:.|..::|.|
Mosquito  2228 SLVDYERVLVLEQGRIVEDGCPRK-LAGKPGSKFGTMLKAT 2267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	394/1601 (25%)
Sur	XP_061511301.1	None