Protein Alignment CG31792 and abcc3

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: XP_009304645.1
• Gene: abcc3 / 323301
• ZFINID: ZDB-GENE-050517-16
• Length: 1540
• Species: Danio rerio
• Alignment Length: 1412
• Identity: 478/1412 - (33%)
• Similarity: 737/1412 - (52%)
• Gaps: 201/1412 - (14%)

  Fly    13 PRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWANELETNK---- 73
            |...:...|.::||:.....|||.|..|..|||:...|...:|.:...|.:.|  |:|.:|
Zfish   204 PETTAGFLSRMTFWWFTRMAIKGYKSPLENKDLWSLNKNDSSELVVPGLLNQW--EVEKSKAHSS 266

  Fly    74 -----------------------------------------KNASLLRVLFRVFGRYFVFLGLVL 97
                                                     :..|.|..|.|.||.||: :|...
Zfish   267 DDQNVKEQVTFTKPGSGAESNHVNESPEEAEVLLSKQQQKSRQPSFLWALLRAFGPYFL-IGSAF 330

  Fly    98 FCLEVILT-VQPMFLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVILMN---PYSFAVTHLG 158
            ..|:.::| :.|. |::::.:|:..|...:...||.|..:...|.|:.::::   .|.|..   |
Zfish   331 KLLQDLITFINPQ-LLRMLIAFTKQSDVPSWWGYALAFLMFGTSLLQTLILHQHFQYCFVT---G 391

  Fly   159 LKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYL 223
            :::|.|:...||||.|.:|.......:.|.::||:|.|..|......|.:.||.||||..:..:.
Zfish   392 MRLRTGIIGAIYRKALVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIFLALFF 456

  Fly   224 MYQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWEL 288
            ::|.:|.:.:.|:..::|.||...::..|....:::.....|.|:::|.||:.||:|:|:||||.
Zfish   457 LWQNLGPSVLAGVAVMVLLIPFNAFIAMKTRTYQVEQMKYKDDRIKLMNEILNGIKVLKLYAWEP 521

  Fly   289 PFEKMVAHARHKEINSIRHVAYAKCL---IWSFNRFLTPVSIFLSLVGFVLMGRFLTAEVAFLIT 350
            .|...:...|.||::.:|..||...|   .|:...||..::.|...|. |.....|.||.||:..
Zfish   522 SFRDKILQIRQKELHVLRKTAYLSALSTMAWTSAPFLVALTSFAVFVN-VDEKNVLDAEKAFVSL 585

  Fly   351 AYYNVVR--TNMTAYFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDENVVSNGAEEDLQEAREKL 413
            :.:|::|  .||.......:.|.:   ||:||:|..|              |..|.|.:..
Zfish   586 SLFNILRFPLNMLPQVISSIVQAS---VSLKRLQDFL--------------NHDELDPESV---- 629

  Fly   414 LVTPTPMRAPEKPPHNSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSL 478
                      ::..:.:|..||:...|..|.... ...|..:|:.|..|:|:|:|||.|.||:||
Zfish   630 ----------DRKSNTTEYAVSVVNGKFSWAKRD-QVILDNINVLVPQGSLLAVVGHVGCGKTSL 683

  Fly   479 IQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFEL 543
            |.|:|||:....|:|.:.||::|..|:.|:.:.|:|.|||||:|...::|..|:..|||..|.|:
Zfish   684 ISALLGEMEKLDGQISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEV 748

  Fly   544 LPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECL--RGHL 606
            ||..|.|.:|::|.:|||||:.|:||||::|.:|.:|||||||||||:.||:.:|:..:  .|.|
Zfish   749 LPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLLDDPLSAVDAHVAKHIFDHVIGPEGAL 813

  Fly   607 RDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDFG----------IVLDDPVN- 660
            :.|..|||||.:.||.|.:.|:::..|:|..:|:|:.|.:....|.          |:.||.:.
Zfish   814 KGKTRILVTHGISFLPQVNNILVLVDGRVSEMGSYQDLLRQNGAFAEFLRNYSLEDIIEDDELTV 878

  Fly   661 ---------------------DNEAAEDRSRTSSITDQRRSSVKS-------VLSHAESC----- 692
                                 |||...:.:|...:   |:.|:.|       .:|....|
Zfish   879 SFDEEEEEFPEDALSNHTDMVDNEPVVNEARRQFM---RQMSIMSNDVENPKKMSRRRRCSERKH 940

  Fly   693 PEDVGE------EQKINLQRQQLGRNGLGVYVDYFRAGGGFLSFSVVMTFFVC----SQGLASLG 747
            ||...|      |:.|..:..:.||..|.||.:|.:|.|..|:      .|:|    .|..|::|
Zfish   941 PETPTEKKEPKVEKLIQAETTETGRVKLQVYWEYVKAIGPLLA------LFICFLYGCQSAAAIG 999

  Fly   748 -DYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAAY-IYMLITVLSIMVTIKRSFLFFNLAMRASI 810
             :::||.|.  |:.:  ||.|.:.......::||. |...:.:|||.: :.|::    ..:||:.
Zfish  1000 ANFWLSEWT--NDAL--HNRTQEMLQTRVGVYAALGISQGVLILSICL-LCRAY----STLRAAR 1055

  Fly   811 QLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIV 875
            ..|..|...:.||...||...|:|.:|||||||:..:|.::|..|...::.|......::|.:::
Zfish  1056 HTHQHMLNSVLRAPQAFFEATPSGRVLNRFSKDVDTIDSLIPDNIDIWMRTFWYTVNVLMVCSVL 1120

  Fly   876 NPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEA 940
            .|:|||..:...:..::::.||:.||..:||||:.:|||:||||:.|:.|.|.|||:|..:....
Zfish  1121 TPIFLIVIVPLMLFYWWVQRFYVATSRQLKRLESVSRSPIYSHFSESITGTSVIRAYGRNAAFVL 1185

  Fly   941 EFDGYQDMHSSASYMFISTSRAFAYWMDI-------FCVLFIAMITLSFFIFPPSSAAD------ 992
            ..|...|.:..:.|..|.::|    |:.:       ..|||.|:..:        :..|
Zfish  1186 MSDNKVDENQKSYYPGIVSNR----WLGVRIEFIGNCIVLFAALFAV--------TGKDKLSPGL 1238

  Fly   993 VGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKI 1057
            |||:::.|:.:|.::.|.||.:::||:.:::|||:.||.|.:.|.|.| ..:|||...||..|.:
Zfish  1239 VGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETQTEAPWE-VLEKKPPPDWPPLGNV 1302

  Fly  1058 EFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFR-LSYNDGSVRIDDK 1121
            |||:.|:||...|  :.|||::|..::..||:||||||||||||:...||| |....|.:.|||.
Zfish  1303 EFVDYSVRYREGL--DLVLKNISLKVRGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEIVIDDV 1365

  Fly  1122 DTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLET 1186
            ..:::||||||||::||||||||||||:|.|||||:.|||:.:|.|||...|:..|.:.|..||.
Zfish  1366 KISEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFERYSDEEVWKALELSHLQKFVTNQAAKLEL 1430

  Fly  1187 KITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAH 1251
            :.:|||.|.|||||||||||||:||..||||:|||||.||.:||.|||:|||.:|::|||.|:||
Zfish  1431 ECSEGGENLSVGQRQLVCLARALLRKTRILVLDEATAAVDLETDDLIQSTIRTEFQDCTVFTIAH 1495

  Fly  1252 RLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQA 1298
            ||:||||..||||:|.|::.||.||..|:  :....|..:.|..|.|
Zfish  1496 RLNTIMDYTRVLVLDKGQIAEFDTPTNLM--NQKGLFFGMAKDAGLA 1540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	478/1412 (34%)
abcc3	XP_009304645.1	MRP_assoc_pro	10..1539	CDD:188098	476/1409 (34%)