Protein Alignment CG31792 and Abcc6

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: XP_006541009.1
• Gene: Abcc6 / 27421
• MGIID: 1351634
• Length: 1500
• Species: Mus musculus
• Alignment Length: 1261
• Identity: 378/1261 - (29%)
• Similarity: 610/1261 - (48%)
• Gaps: 133/1261 - (10%)

  Fly     4 FKNEDLPEN--PRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSW- 65
            |..:..|.|  |...::..|...||:......:|.|..||.|||:...:|:.:|.|.::|...|
Mouse   267 FSEDSQPLNPCPEAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWR 331

  Fly    66 --ANELETNKKNAS-------------------LLRVLFRVFGRYFVFLGLVLFCLEVILTVQPM 109
              .|.|..:|.::|                   |||.::|||...|:...|.|...:......|.
Mouse   332 RSCNGLPGHKGHSSVGAPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPK 396

  Fly   110 FLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCL 174
             |:.|...|.....:|....:..|..:...:.|:.:....:.:....|.:::|..::.::|||.|
Mouse   397 -LLSLFLEFMGDRNSSAWTGWLLAVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVL 460

  Fly   175 RLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFI 239
            .|:.......:.|.::||:|.|:.|:...|.:.:.|||..|...:....::|.:|.:|:..:...
Mouse   461 VLSSGSRKSSAAGDVVNLVSVDIQRLAESIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVF 525

  Fly   240 LLFIPLQMYLGKKISGLRLKTAIRSD-KRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEIN 303
            |..:||..::.|| .|...:..:|.. .|.|:.:.::..::.||.:.||..|.:.:.|.|.:|::
Mouse   526 LSLLPLNFFITKK-RGFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWEHAFLERLLHIRGQELS 589

  Fly   304 SIRHVAYAKCLIWSFNRFLTPVSIFL-SLVGF-----VLMGRFLTAEVAFLITAYYNVVRTNMTA 362
            :::    ...|::|.:.....||.|| :||.|     |.....:.||.||:.....::: ....|
Mouse   590 ALK----TSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSIL-NKAQA 649

  Fly   363 YFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDEN--VVSNGAEEDLQEAREKLLVTPTPMRAPEK 425
            :....|....:..||..|:...|...||   |.|  :.||..
Mouse   650 FLPFSVHCIVQARVSFDRLAAFLCLEEV---DPNGMIASNSR----------------------- 688

  Fly   426 PPHNSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVES 490
              .:|:|.:|:......|:..||. .|.|:||.|..|.|:|:||..|:|||||:.|:||||....
Mouse   689 --RSSKDRISVHNGTFAWSQESPP-CLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVE 750

  Fly   491 GEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDR 555
            |.:.:.||::|..||.|:.:.:|.:|:.|.|.:|......|:..|||..|....|....|.:|::
Mouse   751 GSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQ 815

  Fly   556 GASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECL--RGHLRDKIVILVTHQL 618
            |.:||||||.|:||||:||:.|:||||||||:|:|:.|::::|::.:  .|.|:....|||||.|
Mouse   816 GMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTL 880

  Fly   619 QFLQQADQIVIMEMGKVKAVGTYES-LHKSGLDFGIVLD---DPVNDNEAA-------------- 665
            ..|.|||:|:::..|.:..:|:|:. |.::|...|: ||   .|...::||
Mouse   881 HVLPQADRILVLANGTIAEMGSYQDLLQRNGALVGL-LDGARQPAGTHDAATSDDLGGFPGGGRP 944

  Fly   666 ---EDRSRTSSITDQRRSSVKSVLSHAE-SCPEDVG---EEQKINLQRQQLGRNGLGVYVDYFRA 723
               .||.|.:.....:..|...|...|. ..||..|   ||..:     :.||....:|:.|.||
Mouse   945 TCRPDRPRPTEAAPVKGRSTSEVQMEASLDDPEATGLTAEEDSV-----RYGRVKTTIYLSYLRA 1004

  Fly   724 GGGFLSFSVVMTFFVCSQGLASLGDYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAA---YIYML 785
            .|..|. :..:..|:|.|..:....|:||.|        |.:...|.:    :||||   :::.|
Mouse  1005 VGTPLC-TYTLFLFLCQQVASFSQGYWLSLW--------ADDPVVDGR----QMHAALRGWVFGL 1056

  Fly   786 ITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEM 850
            :..|..:.........|....|||..|..|:...::|:.:.||.:.|.|::||||||:...||..
Mouse  1057 LGCLQAIGLFASMAAVFLGGARASGLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDTVDVD 1121

  Fly   851 LP---TIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTR 912
            :|   ..::|.....|..|   :.:.:..||.::..|...::....:|.|:.||..::|||::..
Mouse  1122 IPDKLRSLLTYAFGLLEVG---LAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARY 1183

  Fly   913 SPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIF--CVLFI 975
            |.|.||.|.:..|...:|||.|.:...|:.|...|.:...|:..:...|..|..:::.  .::|:
Mouse  1184 SSVCSHMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFV 1248

  Fly   976 AMITLSFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLE 1040
            | .|.:.......||..||.:::.|:.:|.|:||.||...:|||:|::|||:.:|..|..|.|..
Mouse  1249 A-ATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWR 1312

  Fly  1041 -ATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLIN 1104
             .|...:|  .||..|:|||.:..||:.|.|  ...::.:|..|...||||||||||||||||..
Mouse  1313 LPTCAAQP--LWPCGGQIEFRDFGLRHRPEL--PLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAW 1373

  Fly  1105 ALFRL-SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCAL 1168
            .|.|| ...:|::.||......:|||.|||:|:||||:||||.|::|.|||...|::|:.:|.||
Mouse  1374 GLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAAL 1438

  Fly  1169 EEVELKDVVASVATGLETKITEGGSN 1194
            |.|:||..|.|:...|:.:....|.:
Mouse  1439 ETVQLKAFVTSLPGQLQYECAGQGDD 1464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	377/1258 (30%)
Abcc6	XP_006541009.1	MRP_assoc_pro	101..1465	CDD:188098	378/1261 (30%)